WGU Pathophysiology Final Exam Questions and answers update

WGU Pathophysiology Final Exam QUESTIONS AND A
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NSwers 2026\2027 UPDATE
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1. Whilebperformingbthebgenitalbassessmentbofbabmalebclient,babnursebobservesbthatbthebclientbhasb
b


curvaturebofbthebpenis.bWhichbconditionbdoesbthebnursebsuspectbinbthebclient?-
ANS>>Peyronie'sbdisease


2. Abclientbtellsbabnurse,b"Myberectionsblastsbforbseveralbhoursbandbarebpainful.b"Whichb
medicationbfoundbinbthebclient'sbprescriptionbisbresponsible?-ANS>>Sildenafil


3. Abnursebobservesbthatbabnewbornbhasbanbabnormallybpositionedburethralborificebofbthebpenis.b
Whichbdisorderbwillbthebnursebsuspectbinbthebnewborn?-ANS>>Hypospadias


4. Whichbphysicalbfindingbinbabclientbwillbleadbabnursebtobsuspectbparaphimosis?-
ANS>>Permanentbretractedbpositionbofbthebforeskinbbehindbthebpenis


5. Abregisteredbnursebisbteachingbaboutbthebmedicationsbforbbenignbprostaticbhyperplasiab(BPH)b
tobabgroupbofbstudentbnurses.bWhichbstatementbofbabstudentbnursebindicatesbthebneedbforbfurt
herbteaching?-ANS>>"Alpha-blockersbREDUCEbthebsizebofbthebprostate."


6. WhichbhormonebstimulatesbSertolibcellsbtobsynthesizebspermatozoa?-ANS>>Follicle-
stimulatingbhormoneb(FSH)


7. Whilebassessingbabmalebclientbforbreproductivebdisorders,bthebprimarybhealth-
carebproviderbwantsbtobunderstandbwhetherbthebclientbhasbprostatebcancerborbbenignbprostati
cbhyperplasiab(BPH).bWhichbdiagnosticbtestbwillbthebnursebexpectbinbthisbcase?-
ANS>>BothbAbandbB
8. (Ultrasound
9. Urine flow studies)
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10. Whilebassessingbabmalebclient,babnursebfindsberythema,bswelling,bandbtendernessbofbtheb
scrotum.bThebclientbalsobreportsbpainbinbthebscrotum.bWhichbdisorderbdoesbthebnursebsuspectb
inbthebclient?-ANS>>Testicularbtorsion


11. Abdigitalbrectalbexaminationb(DRE)binbabclientbrevealsbthebenlargementbofbthebprostatebgla
ndbthatbisbfirm,bpainless,bandbgeneralized.bWhichbmedicationsbwillbthebnursebanticipatebfrombthe
bprimarybhealth-carebproviderbtobtreatbthebclient?-ANS>>Alpha-blockersb&b5-alpha-


reductasebinhibitors

,12. Alpha-
blockersbhelpbtobrelaxbthebsmoothbmusclesbofbthebprostatebbutbdobnotbaidbinbreducingbtheb
sizebofbthebprostate.


13. Whilebassessingbabmalebclient,babnursebobservesbswellingbinbthebscrotumbduebtobtheb
collectionbofbserousbfluid.bWhichbconditionbdoesbthebnursebsuspectbinbthebclient?-
ANS>>HYDROcele


14. WhichbdisorderbcanboccurbduebtobHIV?-ANS>>Testicularbcancer


15. Whichbarterybprovidesbengorgementbofbthebglansbduringberection?-ANS>>Dorsal


16. Afterbexaminingbanbelderlybclient'sbpenis,babnursebfindsbthebpresencebofbscarbtissuebinb
thebcorporabcavernosum.bOnbfurtherbassessment,bthebnursebconfirmsbPeyronie'sbdiseasebinb
thebclient.bWhichbfindingbsupportsbthebnurse'sbconfirmation?-
ANS>>Presencebofbabcurvedbpenis


17. Abnursebteachesbinterventionbtobabclientbforbhealthybspermatogenesis.bDuringbabfollow-
upbvisit,bthebnursebfindsbthatbthebclientbhasbriskbforbdiminishedbspermbproduction.bWhichbstat
ementbofbthebclientbsupportsbthebnurse'sbconclusion?-
ANS>>"Ibshouldbtakebabhotbbathbregularly."


18. Duringbanbassessment,babnursebobservesbthebsignsbofbdiminishedbsecondarybsexualb
characteristicsbinbanbadultbmalebclient.bWhatbshouldbbebthebappropriatebnursingbaction?-
ANS>>Measurebthebmorningbserumbtestosteroneblevels.


19. WhichbhormonebstimulatesbthebLeydigbcellsbofbthebtestesbtobsecretebtestosterone?-
ANS>>Luteinizingbhormone


20. Whichbcellsbsecretebinhibinbhormone?-ANS>>Sertolibcells


21. Whichbconditionbcanbcausebischemiabofbthebtesticle?-ANS>>Testicularbtorsion


22. Whilebassessingbabmalebclient,babnursebobservesbthatbthebclientbhasbabsmallbpenis,blongbl
egs,bshortbtrunk,benlargedbbreastbtissues,bsmallbtesticles,bandbsexualbdysfunction.bWhatbreas
onbdoesbthebnursebsuspectbfrombthesebfindings?-ANS>>PresencebofbanbextrabXbchromosome


23. Whichbglandbsecretesbablubricatingbfluidbthatbcoatsbtheburethrabduringbsexualbarousal?-
ANS>>Bulbourethralbgland


24. EndocrinebSystem-ANS>>Consistsbofbglandsbsecretingbhormonesbintobthebbloodstream


25. HormonebRegulation-
ANS>>Hormonesbactbonbtargetbcellsbbybbindingbtobspecificbreceptors

,26. HomeostasisbMaintenance-
ANS>>Hormonesbregulatebphysiologicalbparametersbforbinternalbbalance


27. GrowthbandbDevelopment-
ANS>>Hormonesbinfluencebgrowth,bmusclebdevelopment,bandbmaturation


28. StressbResponse-ANS>>Endocrinebsystembreleasesbcortisolbtobadaptbtobstressors


29. AutoimmunebDiseases-
ANS>>Immunebsystembattacksbendocrinebglands,bcausingbdisorders


30. NeoplasticbGrowth-ANS>>Tumorsbinbglandsbdisruptbhormonebproductionbandbfunctions


31. PituitarybGlandbDisorders-
ANS>>Conditionsbaffectingbpituitarybhormonebsecretionblevels


32. Hypopituitarism-ANS>>Underactivitybofbpituitarybglandbcausingbhormonebdeficiencies


33. Hyperpituitarism-ANS>>Overactivitybofbpituitarybglandbleadingbtobhormonebexcess


34. SIADH-ANS>>Excessivebantidiureticbhormonebsecretionbcausingbwaterbretention


35. ThyroidbDisorders-
ANS>>Conditionsbaffectingbthyroidbhormonebproductionbandbfunction


36. Graves'bDisease-ANS>>Autoimmunebhyperthyroidismbwithbgoiterbandbeyebinvolvement


37. Hypothyroidism-
ANS>>Underactivebthyroidbglandbcausingbhormonebdeficiencybsymptoms


38. Thyrotoxicosis-ANS>>Excessivebthyroidbhormonebactivitybinbthebbody


39. AdrenalbGlandbDisorders-
ANS>>Conditionsbaffectingbadrenalbhormonebproductionbandbfunction


40. Cushing'sbDisease-ANS>>HypercortisolismbduebtobexcessivebACTHbproduction


41. Addison'sbDisease-ANS>>Adrenalbinsufficiencybfrombautoimmunebadrenalbdestruction


42. Pheochromocytoma-ANS>>Adrenalbtumorbproducingbexcessbcatecholamines


43. Typeb1bDiabetes-ANS>>Autoimmunebdestructionbofbinsulin-producingbbetabcells


44. Typeb2bDiabetes-ANS>>Insulinbresistancebleadingbtobdecreasedbinsulinbproduction

, 45. DiabeticbKetoacidosisb(DKA)-
ANS>>Severebhyperglycemia,bketosis,bandbmetabolicbacidosis


46. HyperosmolarbHyperglycemicbSyndromeb(HHS)-ANS>>Life-
threateningbhyperglycemia,bhyperosmolarity,bandbdehydration


47. HyperosmolarbHyperglycemicbStateb(HHS)-
ANS>>Occursbinbolderbadultsbwithbtypeb2bdiabetes,bleadingbtobextremebdehydrationbandbalt
eredbconsciousness.


48. Chlamydia-
ANS>>CommonbSTIbcausedbbybChlamydiabtrachomatis,boftenbasymptomaticbbutbcanbcausebPI
Dbandbinfertility.


49. Gonorrhea-
ANS>>STIbcausedbbybNeisseriabgonorrhoeae,bwithbsymptomsblikeburethralbdischargebandbpel
vicbpain.


50. PelvicbInflammatorybDiseaseb(PID)-
ANS>>Infectionbofbfemalebreproductiveborgans,bcommonlybcausedbbybSTIs,bleadingbtobpe
lvicbpainbandbinfertility.


51. LGBTQbSexualbHealthbCare-
ANS>>UniquebcarebneedsbforbLGBTQbindividualsbrelatedbtobsexualborientationbandbgenderbide
ntity.


52. Endometriosis-
ANS>>Conditionbwherebendometrialbtissuebgrowsboutsidebthebuterus,bcausingbpelvicbpainba
ndbinfertility.


53. Adenomyosis-
ANS>>Endometrialbtissuebgrowsbintobthebuterinebwall,bcausingbheavybbleedingbandbpelvicb
pain.


54. PolycysticbOvarianbSyndromeb(PCOS)-
ANS>>Hormonalbdisorderbwithbovarianbcysts,birregularbcycles,bandbsymptomsbofbandrogen
bexcess.




55. HormonebReceptors-ANS>>ER,bPR,bandbHER2bplaybabkeybrolebinbbreastbcancerbbiology.


56. Triple-NegativebBreastbCancerb(TNBC)-
ANS>>RapidbgrowingbBreastbcancerbsubtypeblackingbER,bPR,bandbHER2bexpression,btreate
dbwithbchemotherapy.


57. OvarianbCancer-
ANS>>Malignancybinbovariesbwithbsymptomsblikebbloating,bpelvicbpain,bandbbowelbhabitbchang
es.