APEA Pre-Predictor 2025-2026 Examination
Guide by Amelie Hollier and Mimi Secor:
850+ Verified Questions and Rationales to
Pass Your NP Boards on the First Attempt
and Avoid Resits
| Question | Correct Answer & Rationale |
| :--- | :--- |
| **1. A 15-year-old high school student presents with a mild sore throat and low-grade fever that has
persisted for about 3 weeks. She reports general malaise. The NP suspects mononucleosis. Which of the
following is the LEAST appropriate intervention?** <br/><br/> A. Palpate the lymph nodes and spleen
<br/> B. Prescribe a 10-day course of amoxicillin <br/> C. Obtain a complete blood count with
differential <br/> D. Recommend symptomatic care with rest and hydration | **B. Prescribe a 10-day
course of amoxicillin** <br/><br/> **Rationale:** Amoxicillin and other aminopenicillins are
contraindicated in infectious mononucleosis because they frequently cause a diffuse, maculopapular
rash that is not a true allergic reaction but can be mistaken for one. Symptomatic care is the mainstay of
treatment, and careful abdominal palpation is indicated to assess for splenomegaly. A CBC with
differential can show lymphocytosis and atypical lymphocytes, supporting the diagnosis. |
| **2. An APEA Pre-Predictor exam is best described as:** <br/><br/> A. A 150-question, 3-hour timed
assessment given at the start of the final semester <br/> B. A 50-question, un-timed assessment used to
practice test-taking strategies <br/> C. An open-book, non-proctored exam completed in the student's
own time <br/> D. A 300-question exam taken after all coursework is complete | **A. A 150-question, 3-
hour timed assessment given at the start of the final semester** <br/><br/> **Rationale:** The APEA
Pre-Predictor is a 3-hour exam with 150 questions. It is administered at the beginning of the last
semester to identify weaknesses so students can remediate before taking the later Predictor Exams. |
| **3. A patient presents with distorted areas and blind spots in the visual field. The painless condition is
identified as macular degeneration. Which of the following is a primary risk factor for this condition?**
<br/><br/> A. Age <br/> B. Diabetes mellitus <br/> C. Hypertension <br/> D. Glaucoma | **A. Age**
<br/><br/> **Rationale:** Age is the single most important risk factor for age-related macular
Guide by Amelie Hollier and Mimi Secor:
850+ Verified Questions and Rationales to
Pass Your NP Boards on the First Attempt
and Avoid Resits
| Question | Correct Answer & Rationale |
| :--- | :--- |
| **1. A 15-year-old high school student presents with a mild sore throat and low-grade fever that has
persisted for about 3 weeks. She reports general malaise. The NP suspects mononucleosis. Which of the
following is the LEAST appropriate intervention?** <br/><br/> A. Palpate the lymph nodes and spleen
<br/> B. Prescribe a 10-day course of amoxicillin <br/> C. Obtain a complete blood count with
differential <br/> D. Recommend symptomatic care with rest and hydration | **B. Prescribe a 10-day
course of amoxicillin** <br/><br/> **Rationale:** Amoxicillin and other aminopenicillins are
contraindicated in infectious mononucleosis because they frequently cause a diffuse, maculopapular
rash that is not a true allergic reaction but can be mistaken for one. Symptomatic care is the mainstay of
treatment, and careful abdominal palpation is indicated to assess for splenomegaly. A CBC with
differential can show lymphocytosis and atypical lymphocytes, supporting the diagnosis. |
| **2. An APEA Pre-Predictor exam is best described as:** <br/><br/> A. A 150-question, 3-hour timed
assessment given at the start of the final semester <br/> B. A 50-question, un-timed assessment used to
practice test-taking strategies <br/> C. An open-book, non-proctored exam completed in the student's
own time <br/> D. A 300-question exam taken after all coursework is complete | **A. A 150-question, 3-
hour timed assessment given at the start of the final semester** <br/><br/> **Rationale:** The APEA
Pre-Predictor is a 3-hour exam with 150 questions. It is administered at the beginning of the last
semester to identify weaknesses so students can remediate before taking the later Predictor Exams. |
| **3. A patient presents with distorted areas and blind spots in the visual field. The painless condition is
identified as macular degeneration. Which of the following is a primary risk factor for this condition?**
<br/><br/> A. Age <br/> B. Diabetes mellitus <br/> C. Hypertension <br/> D. Glaucoma | **A. Age**
<br/><br/> **Rationale:** Age is the single most important risk factor for age-related macular
