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NBME Practice COMPLETE HIGH-YIELD STUDY GUIDE WITH PRACTICE QUESTIONS AND VERIFIED ANSWERS

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NBME Practice COMPLETE HIGH-YIELD STUDY GUIDE WITH PRACTICE QUESTIONS AND VERIFIED ANSWERS

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a 14 year old boy has a 3 year history of type 1 diabetes mellitus. He injects himself with
insulin twice daily. When he goes to summer cap, he stops taking his insulin because he
does not want to seem different from his peers. After 23 hours without his insulin dose,
he develops abdominal pain and vomitting and becomes disoriented and difficult to
arouse. He is taken to the local hospital. On admission to the hospital, he is most likely to
have an increased serum glucose concentration and which of the following finds in
arterial blood?


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,An 18 year old man undergoes removal of 75% of the liver following a gunshow wound.
In the remaining hepatocytes, the first change in cell cyle distribution will be movement
of cells between which of the following phases


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G0 to G1 - Cycle D




Fructose 2,6-bisphosphate regulates which step in the diagram?


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C- glucose 6 phosphate conversion to pyruvate




a 45 year old man with increased serum LDL concentrations is treated with
cholestyramine, which binds bile salts in the small intestine. the most likely result is
prevention of which of the following?


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Resorption and redistribution of bile salts to the liver

,Diacylglycerol most likely acts as a second messenger by activation of which of the
following proteins?


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Protein Kinase C




What is the major consequence of a hereditary defect in the production of active
pyruvate kinase in the liver and in erythrocytes


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Decreased production of ATP from glucose




Carbon dioxide produced by tissue metabolism is carried in the blood predominantly in
which of the following forms q


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HCO3- in plasma




a 28 year old man is brought to the emergency department after being lost in a remote
wilderness area for 3 weeks. He consumed all of the food in his backpack 2 weeks ago
and has had only wild berries and pond water since then. Intravenous feeing is begun.
Blood samples obtained before intravenous feeding was begun show increased serum

, concentrations of ketone bodies and urea nitrogen (BUN); glucose concentration is
whtin the referance range. Use of which of the following best explains the maintenance
of a normal glucose concentration in this patient?


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Skeletal muscle protein - will get broken down during ketogenesis




After 6 hours of excruciating pain, a 26 year old man passes a 3 mm calculus. the
calculus is most likely to be composed primarily of?


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Caclium salts




a 1 year old boy is brought to the emergency department because he is having difficulty
breathing after drinking water that contains nitrate. He is cyanotic. Blood drawn from the
lab studies is chocolate colored. His hemoglobin most likely has which of the following
properties?


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Increase proportion of Fe2+




Prostacylin synthesized by the endothelial cells promotes which of the following?


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