Page 1 of 158
COMSAE Phase 2 Form 113 EXAM QUESTIONS AND
VERIFIED ANSWERS WITH RATIONALES JUST
RELEASED
COMSAE Phase 2 Form 113 (BSA 113i) Exam preparation package. I have synthesized the exam
coverage based on the official NBOME blueprint for COMLEX-USA Level 2-CE (which COMSAE Phase 2
mirrors) and the available search results from actual Form 113 questions . This is followed by 250
original, exam-style multiple-choice questions, each with a single best answer and a detailed rationale.
POINT-FORM SUMMARIZED EXAM COVERAGE
COMSAE Phase 2 / COMLEX-USA Level 2-CE Blueprint
o .
• Core Clinical COntent Domains (Weighted)
o Obstetrics & Gynecology (≈7–12%)
▪ Antepartum complications (preeclampsia, gestational diabetes, bleeding,
infections)
▪ Intrapartum management (labor dystocia, fetal distress, shoulder dystocia)
▪ Postpartum care (hemorrhage, endometritis, mood disorders)
▪ Gynecologic conditions (endometriosis, fibroids, ovarian cysts, abnormal uterine
bleeding, STIs)
▪ Breast disorders (benign masses, malignancy screening, genetics)
o Internal Medicine & Subspecialties (≈30–35%)
▪ Cardiology: Coronary artery disease (STEMI/NSTEMI management), heart failure
(HFrEF vs. HFpEF), arrhythmias (AFib, SVT, VT, bradyarrhythmias), valvular
disease, hypertension, pericarditis, aortic dissection.
▪ Pulmonology: COPD exacerbation (oxygen therapy thresholds), asthma,
pneumonia, pulmonary embolism (diagnosis, anticoagulation), interstitial lung
disease.
▪ Gastroenterology: GERD, peptic ulcer disease, GI bleeding (variceal vs. non-
variceal), inflammatory bowel disease (UC vs. Crohn's), hepatitis, pancreatitis,
colorectal cancer screening.
▪ Nephrology: Acute kidney injury (prerenal, intrinsic, postrenal), chronic kidney
disease (management, dialysis indications), glomerulonephritis (nephritic vs.
nephrotic), electrolyte disorders.
▪ Endocrinology: Diabetes mellitus (type 1 vs. 2, complications, management),
thyroid disorders (hyperthyroidism, hypothyroidism, thyroid nodules), adrenal
disorders (pheochromocytoma, adrenal insufficiency), osteoporosis.
▪ Rheumatology: Rheumatoid arthritis, systemic lupus erythematosus (lupus
nephritis, management ), gout, seronegative spondyloarthropathies.
▪ Hematology/Oncology: Anemia (microcytic, macrocytic, hemolytic), bleeding
disorders (hemophilia, vWF), thrombophilia, leukemia (CML, AML), lymphoma,
breast/lung/colon cancer (screening, markers, targeted therapy).
o Pediatrics (≈8–10%)
▪ Neonatology (jaundice, respiratory distress, feeding issues)
▪ Infectious diseases (croup, epiglottitis, bronchiolitis, meningitis)
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▪ Genetic and congenital disorders (Down syndrome, VATER, etc.)
▪ Growth and development milestones
▪ Pediatric emergencies (intussusception , testicular torsion, toxic ingestions)
o Surgery & Surgical Specialties (≈8–10%)
▪ Acute abdomen (appendicitis, cholecystitis, bowel obstruction, pancreatitis)
▪ Trauma management (primary survey, shock, specific injuries)
▪ Preoperative and postoperative care (risk assessment, complications: DVT,
infection)
▪ Vascular surgery (peripheral artery disease, AAA, carotid stenosis)
o Neurology & Psychiatry (≈8–10%)
▪ Neurology: Stroke (ischemic vs. hemorrhagic, tPA criteria), seizure disorders,
headache (migraine, cluster, tension), multiple sclerosis, Parkinson disease,
Guillain-Barré syndrome, meningitis/encephalitis , myasthenia gravis.
▪ Psychiatry: Major depression, bipolar disorder, anxiety disorders, psychosis
(schizophrenia), substance use disorders (alcohol withdrawal, Wernicke
encephalopathy) , eating disorders, suicide risk assessment.
o Osteopathic Principles & Practice (OPP) – Integrated
▪ Somatic dysfunction diagnosis and treatment (HVLA, muscle energy,
counterstrain, Chapman reflexes)
▪ Viscerosomatic reflexes (somatic findings associated with visceral pathology)
▪ Cranial and sacral diagnosis
▪ OMT for specific clinical conditions (low back pain, headaches, asthma, GI
disorders)
o Emergency Medicine (≈5–8%)
▪ Resuscitation (ACLS algorithms, airway management, shock)
▪ Toxicologic emergencies (overdoses, withdrawal)
▪ Environmental emergencies (hypothermia, heat stroke)
▪ Orthopedic emergencies (fractures, dislocations, compartment syndrome)
o Ethics, Legal & Preventive Medicine (≈5%)
▪ Patient confidentiality, informed consent, capacity, advance directives
▪ Screening guidelines (USPSTF: cancer, hypertension, hyperlipidemia, AAA)
▪ Vaccination schedules (childhood, adult, travel)
▪ Reportable diseases and public health reporting
• High-Yield Question Formats (from Form 113)
o Next best step in diagnosis or management
o Most likely diagnosis based on classic presentation (e.g., RLQ pain + rebound =
appendicitis ; painless hematuria in smoker = bladder cancer )
o Interpretation of labs, imaging, or pathology findings
o Identification of medication side effects or interactions
o Selection of appropriate therapy based on evidence-based guidelines
o OPP integration (viscerosomatic reflexes, Chapman points, OMT for specific conditions)
250 ORIGINAL COMSAE-STYLE MCQ QUESTIONS
Form 113 (BSA 113i) Exam Preparation
, Page 3 of 158
*Written in the style of COMSAE Phase 2. Each question includes the best single answer and a high-yield
rationale.*
Section 1: Obstetrics & Gynecology (Questions 1–30)
1. A 28-year-old G1P0 at 34 weeks gestation presents with a blood pressure of 155/100 mm Hg and 2+
proteinuria. She reports a severe headache and epigastric pain. Which is the most appropriate next
step?
A) Oral labetalol and outpatient monitoring
B) IV magnesium sulfate and delivery after corticosteroid administration
C) Immediate cesarean delivery
D) Methyldopa and expectant management
Answer: B
Rationale: Severe preeclampsia at ≥32 weeks requires delivery after stabilization. Magnesium sulfate is
given for seizure prophylaxis, and antenatal corticosteroids are administered if <37 weeks .
, Page 4 of 158
2. A 24-year-old G1P0 at 10 weeks gestation presents with vaginal spotting and mild cramping. On
speculum exam, the os is closed. Transvaginal ultrasound shows a live intrauterine pregnancy. What is
the most appropriate management?
A) Misoprostol for evacuation
B) Immediate D&C
C) Rh immunoglobulin if mother is Rh-negative, and reassurance
D) Serial beta-hCG monitoring only
Answer: C
Rationale: Threatened abortion (closed os, viable pregnancy) is managed conservatively with
reassurance. Rh-negative mothers require Rh immunoglobulin to prevent sensitization .
3. A 32-year-old G2P1 at 28 weeks gestation has a 1-hour glucose challenge test result of 155 mg/dL.
Which is the most appropriate next step?
A) Diagnosis of gestational diabetes and initiate metformin
B) Repeat glucose challenge test in 1 week
C) 3-hour oral glucose tolerance test (OGTT)
D) Fasting blood glucose monitoring for 1 week
COMSAE Phase 2 Form 113 EXAM QUESTIONS AND
VERIFIED ANSWERS WITH RATIONALES JUST
RELEASED
COMSAE Phase 2 Form 113 (BSA 113i) Exam preparation package. I have synthesized the exam
coverage based on the official NBOME blueprint for COMLEX-USA Level 2-CE (which COMSAE Phase 2
mirrors) and the available search results from actual Form 113 questions . This is followed by 250
original, exam-style multiple-choice questions, each with a single best answer and a detailed rationale.
POINT-FORM SUMMARIZED EXAM COVERAGE
COMSAE Phase 2 / COMLEX-USA Level 2-CE Blueprint
o .
• Core Clinical COntent Domains (Weighted)
o Obstetrics & Gynecology (≈7–12%)
▪ Antepartum complications (preeclampsia, gestational diabetes, bleeding,
infections)
▪ Intrapartum management (labor dystocia, fetal distress, shoulder dystocia)
▪ Postpartum care (hemorrhage, endometritis, mood disorders)
▪ Gynecologic conditions (endometriosis, fibroids, ovarian cysts, abnormal uterine
bleeding, STIs)
▪ Breast disorders (benign masses, malignancy screening, genetics)
o Internal Medicine & Subspecialties (≈30–35%)
▪ Cardiology: Coronary artery disease (STEMI/NSTEMI management), heart failure
(HFrEF vs. HFpEF), arrhythmias (AFib, SVT, VT, bradyarrhythmias), valvular
disease, hypertension, pericarditis, aortic dissection.
▪ Pulmonology: COPD exacerbation (oxygen therapy thresholds), asthma,
pneumonia, pulmonary embolism (diagnosis, anticoagulation), interstitial lung
disease.
▪ Gastroenterology: GERD, peptic ulcer disease, GI bleeding (variceal vs. non-
variceal), inflammatory bowel disease (UC vs. Crohn's), hepatitis, pancreatitis,
colorectal cancer screening.
▪ Nephrology: Acute kidney injury (prerenal, intrinsic, postrenal), chronic kidney
disease (management, dialysis indications), glomerulonephritis (nephritic vs.
nephrotic), electrolyte disorders.
▪ Endocrinology: Diabetes mellitus (type 1 vs. 2, complications, management),
thyroid disorders (hyperthyroidism, hypothyroidism, thyroid nodules), adrenal
disorders (pheochromocytoma, adrenal insufficiency), osteoporosis.
▪ Rheumatology: Rheumatoid arthritis, systemic lupus erythematosus (lupus
nephritis, management ), gout, seronegative spondyloarthropathies.
▪ Hematology/Oncology: Anemia (microcytic, macrocytic, hemolytic), bleeding
disorders (hemophilia, vWF), thrombophilia, leukemia (CML, AML), lymphoma,
breast/lung/colon cancer (screening, markers, targeted therapy).
o Pediatrics (≈8–10%)
▪ Neonatology (jaundice, respiratory distress, feeding issues)
▪ Infectious diseases (croup, epiglottitis, bronchiolitis, meningitis)
, Page 2 of 158
▪ Genetic and congenital disorders (Down syndrome, VATER, etc.)
▪ Growth and development milestones
▪ Pediatric emergencies (intussusception , testicular torsion, toxic ingestions)
o Surgery & Surgical Specialties (≈8–10%)
▪ Acute abdomen (appendicitis, cholecystitis, bowel obstruction, pancreatitis)
▪ Trauma management (primary survey, shock, specific injuries)
▪ Preoperative and postoperative care (risk assessment, complications: DVT,
infection)
▪ Vascular surgery (peripheral artery disease, AAA, carotid stenosis)
o Neurology & Psychiatry (≈8–10%)
▪ Neurology: Stroke (ischemic vs. hemorrhagic, tPA criteria), seizure disorders,
headache (migraine, cluster, tension), multiple sclerosis, Parkinson disease,
Guillain-Barré syndrome, meningitis/encephalitis , myasthenia gravis.
▪ Psychiatry: Major depression, bipolar disorder, anxiety disorders, psychosis
(schizophrenia), substance use disorders (alcohol withdrawal, Wernicke
encephalopathy) , eating disorders, suicide risk assessment.
o Osteopathic Principles & Practice (OPP) – Integrated
▪ Somatic dysfunction diagnosis and treatment (HVLA, muscle energy,
counterstrain, Chapman reflexes)
▪ Viscerosomatic reflexes (somatic findings associated with visceral pathology)
▪ Cranial and sacral diagnosis
▪ OMT for specific clinical conditions (low back pain, headaches, asthma, GI
disorders)
o Emergency Medicine (≈5–8%)
▪ Resuscitation (ACLS algorithms, airway management, shock)
▪ Toxicologic emergencies (overdoses, withdrawal)
▪ Environmental emergencies (hypothermia, heat stroke)
▪ Orthopedic emergencies (fractures, dislocations, compartment syndrome)
o Ethics, Legal & Preventive Medicine (≈5%)
▪ Patient confidentiality, informed consent, capacity, advance directives
▪ Screening guidelines (USPSTF: cancer, hypertension, hyperlipidemia, AAA)
▪ Vaccination schedules (childhood, adult, travel)
▪ Reportable diseases and public health reporting
• High-Yield Question Formats (from Form 113)
o Next best step in diagnosis or management
o Most likely diagnosis based on classic presentation (e.g., RLQ pain + rebound =
appendicitis ; painless hematuria in smoker = bladder cancer )
o Interpretation of labs, imaging, or pathology findings
o Identification of medication side effects or interactions
o Selection of appropriate therapy based on evidence-based guidelines
o OPP integration (viscerosomatic reflexes, Chapman points, OMT for specific conditions)
250 ORIGINAL COMSAE-STYLE MCQ QUESTIONS
Form 113 (BSA 113i) Exam Preparation
, Page 3 of 158
*Written in the style of COMSAE Phase 2. Each question includes the best single answer and a high-yield
rationale.*
Section 1: Obstetrics & Gynecology (Questions 1–30)
1. A 28-year-old G1P0 at 34 weeks gestation presents with a blood pressure of 155/100 mm Hg and 2+
proteinuria. She reports a severe headache and epigastric pain. Which is the most appropriate next
step?
A) Oral labetalol and outpatient monitoring
B) IV magnesium sulfate and delivery after corticosteroid administration
C) Immediate cesarean delivery
D) Methyldopa and expectant management
Answer: B
Rationale: Severe preeclampsia at ≥32 weeks requires delivery after stabilization. Magnesium sulfate is
given for seizure prophylaxis, and antenatal corticosteroids are administered if <37 weeks .
, Page 4 of 158
2. A 24-year-old G1P0 at 10 weeks gestation presents with vaginal spotting and mild cramping. On
speculum exam, the os is closed. Transvaginal ultrasound shows a live intrauterine pregnancy. What is
the most appropriate management?
A) Misoprostol for evacuation
B) Immediate D&C
C) Rh immunoglobulin if mother is Rh-negative, and reassurance
D) Serial beta-hCG monitoring only
Answer: C
Rationale: Threatened abortion (closed os, viable pregnancy) is managed conservatively with
reassurance. Rh-negative mothers require Rh immunoglobulin to prevent sensitization .
3. A 32-year-old G2P1 at 28 weeks gestation has a 1-hour glucose challenge test result of 155 mg/dL.
Which is the most appropriate next step?
A) Diagnosis of gestational diabetes and initiate metformin
B) Repeat glucose challenge test in 1 week
C) 3-hour oral glucose tolerance test (OGTT)
D) Fasting blood glucose monitoring for 1 week
