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Samenvatting Nociplastische Pijn | Fysiotherapie | HU Utrecht | 2025/26

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Dit studiemateriaal behandelt nociplastische pijn voor het vak fysiologie, Pathologie van het studieblok Zorg en Samenleving (blok C) aan Hogeschool Utrecht. De aantekeningen dekken de pijnpathway, nociceptieve pijnverwerking, spinale mechanismen (WDR-neuronen, centrale sensitisatie), hyperalgesie, allodynie, en onderscheid tussen vitale en gnostische sensibiliteit. Ideaal voor voorbereiding op examens en voor het begrijpen van complexe pijnmechanismen in de fysiotherapie.

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Nociplastische pijn

Pijn:

- Acute pijn (weefselschade) (nociceptive pijn)
- Chronische pijn (pijn die langdurig aanhoud; geen weefselschade op
voorgrond)




Nociceptieve pijn:

The pain pathway

- Perifeer: 1e orde neuronen
- Ruggenmerg: 2e orde neuronen (schakel)
- Hersenen: 3e orde neuronen (schakel)
- Hersenstam (pijncentrum (PAG)

, Perifeer:

A-delts vezel (waarschuwing) (primaire pijn)

C- vezel: SP (perifere sensitisatie) (bescherming) (secundaire pijn)




Ruggenmerg:

Prikkelgeleiding: canvas video’s

1. A-delte vezels: 1e orde neuron (snelste zenuw vezels in het lichaam)
- Naar hersenen
2. Ruggenmerg: 2e orde neuron
3. Hersenen: 3e orde neuron

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Uploaded on
June 13, 2026
Number of pages
12
Written in
2025/2026
Type
SUMMARY

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