NR 507 EXAM 2 LATEST VERSIONS 2026-2027
(VERSION A& B) - NR 507 WEEK 4
ADVANCED PATHOPHYSIOLOGY EXAM
LATEST 2026
1. Examples of hypersensitivity type 1: allergic rhinitis, anaphylactic reaction
2. Type 1 hypersensitivity reactions are mediated by what: IgE
3. What cells are involved in hypersensitivity type 1: Mast cells
4. symptoms of hypersensitivity type 1: local: itching, immediate rash systemic:
wheezing
5. main treatment for anaphylaxis: epinephrine
6. Type 2 hypersensitivity is also known as what kind of reaction?: cytoctoxic
reaction, tissue specific
7. what cells are involved in type 2 hypersensitivity reaction?: Macrophages
8. 8. what does type 2 hypersensitivity do to tissues?: can cause damage or alter
function of specific tissues
9. Examples of hypersensitivity type 2: graves disease/ hyperthyroidism, blood
incompatibility
10. what is the difference between type 2 and 3 hypersensitivity?: type 2 is organ
specific; antibody binds to the antigen on the surface of the cell
type 3 is NOT organ specific; binds outside of the cell surface and is released into blood/
body fluids and then deposited into tissues
11. examples of type 3 hypersensitivity: rheumatoid arthritis and lupus
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, .
12. autoimmune diseases can be...: genetic/familial
13. What is alloimmunity?: Immune reaction to tissues of another individual
14. 14. Examples of alloimmunity: transplant rejection, transfusion reactions, Rh
incompatibility
15. what is hypersensitivity type 4: Delayed response, Occurs 24-72 hrs after
exposure doe not involve antigen/antibody complexes
16. Hypersensitivity type 4 is mediated by what?: T cells!!!
17. 17. example of hypersensitivity type 4: contact dermatitis poison ivy delayed
response occurs in area of contact
18. organ rejection is made up of what hypersensitivity and why?: Type 2 and 4.
involves cytotoxicity (2)
T cells play a role in organ rejection (4)
19. atopic dermatitis is example of what: type 1 hypersensitivity
20. contact dermatitis is example of what: type 4 hypersensitivity
21. Contact dermatitis treatment: topical corticosteroids
22. atopic dermatitis treatment: -Antihistamines
23 what is primary immunodeficiency: Deficiency in any essential component of the
immune response that is mostly recessively inherited; a gene defect;
24. example of primary immunodeficiency: B lymphocyte deficiency
25. what is secondary immunodeficiency and example: Caused by another illness, or
virus. (More common than primary immunodeficiency) Ex: cancer or HIV
26. 26. what is the most common cause of secondary immunodeficiency: malnutrition
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(VERSION A& B) - NR 507 WEEK 4
ADVANCED PATHOPHYSIOLOGY EXAM
LATEST 2026
1. Examples of hypersensitivity type 1: allergic rhinitis, anaphylactic reaction
2. Type 1 hypersensitivity reactions are mediated by what: IgE
3. What cells are involved in hypersensitivity type 1: Mast cells
4. symptoms of hypersensitivity type 1: local: itching, immediate rash systemic:
wheezing
5. main treatment for anaphylaxis: epinephrine
6. Type 2 hypersensitivity is also known as what kind of reaction?: cytoctoxic
reaction, tissue specific
7. what cells are involved in type 2 hypersensitivity reaction?: Macrophages
8. 8. what does type 2 hypersensitivity do to tissues?: can cause damage or alter
function of specific tissues
9. Examples of hypersensitivity type 2: graves disease/ hyperthyroidism, blood
incompatibility
10. what is the difference between type 2 and 3 hypersensitivity?: type 2 is organ
specific; antibody binds to the antigen on the surface of the cell
type 3 is NOT organ specific; binds outside of the cell surface and is released into blood/
body fluids and then deposited into tissues
11. examples of type 3 hypersensitivity: rheumatoid arthritis and lupus
1/7
, .
12. autoimmune diseases can be...: genetic/familial
13. What is alloimmunity?: Immune reaction to tissues of another individual
14. 14. Examples of alloimmunity: transplant rejection, transfusion reactions, Rh
incompatibility
15. what is hypersensitivity type 4: Delayed response, Occurs 24-72 hrs after
exposure doe not involve antigen/antibody complexes
16. Hypersensitivity type 4 is mediated by what?: T cells!!!
17. 17. example of hypersensitivity type 4: contact dermatitis poison ivy delayed
response occurs in area of contact
18. organ rejection is made up of what hypersensitivity and why?: Type 2 and 4.
involves cytotoxicity (2)
T cells play a role in organ rejection (4)
19. atopic dermatitis is example of what: type 1 hypersensitivity
20. contact dermatitis is example of what: type 4 hypersensitivity
21. Contact dermatitis treatment: topical corticosteroids
22. atopic dermatitis treatment: -Antihistamines
23 what is primary immunodeficiency: Deficiency in any essential component of the
immune response that is mostly recessively inherited; a gene defect;
24. example of primary immunodeficiency: B lymphocyte deficiency
25. what is secondary immunodeficiency and example: Caused by another illness, or
virus. (More common than primary immunodeficiency) Ex: cancer or HIV
26. 26. what is the most common cause of secondary immunodeficiency: malnutrition
2/7
