3|NEW UPDATE 2025-2026|ALREADY GRADED A+
EXAM 1
What are the two major divisions of the nervous system?
-Central nervous system (CNS)
-Peripheral nervous system (PNS)
What are the two primary components of the CNS?
-Brain
-Spinal cord
What are the two subdivisions of the peripheral nervous system?
-Somatic nervous system (controls voluntary movements)
-Autonomic nervous system (controls involuntary responses)
What are the two subdivisions of the autonomic nervous system?
-Sympathetic division
-Parasympathetic division
,What is the characteristic set of signs and symptoms produced when the
sympathetic nervous system is activated?
Fight-or-flight response
What is the set of signs and symptoms produced when the parasympathetic
nervous system is activated?
Rest-and-digest response
What are effects of the sympathetic nervous system?
-Dilates pupils
-Inhibits salivation
-Accelerates heart rate, contractility
-Dilates bronchioles
-Stimulates release of glucose
What are effects of the parasympathetic nervous system?
-Constricts pupils
-Stimulates salivation
,-Slows heart rate, contractility
-Constricts bronchioles
What is the primary neurotransmitter of the parasympathetic nervous system?
Acetylcholine (ACh)
What is the role of acetylcholinesterase (AChE)?
An enzyme that destroys acetylcholine (ACh)
What are the receptors of the parasympathetic nervous system called?
Cholinergic
What are drugs that inhibit the parasympathetic nervous system?
Anticholinergic
What are examples of acetylcholinesterase (AChE)/cholinesterase inhibitors?
-Donepezil (Aricept)
-Galantamine (Razadyne)
, -Rivastigmine (Exelon)
What is the MOA of donepezil (Aricept)?
Increases the amount of acetylcholine (ACh) by inhibiting acetylcholinesterase
(AChE)
What is the indication of acetylcholinesterase (AChE)/cholinesterase
inhibitors?
Alzheimer's disease
What is the indication of bethanechol (Urecholine)?
Urinary retention
What is the MOA of bethanechol (Urecholine)?
Binds to cholinergic receptors to produce the rest-and-digest response that
relaxes the bladder
What is a cholinergic crisis?
Symptoms that occur when a patient is given too much cholinergic medication