NR507- Midterm Advanced Patho-
Cardiac, Pulmonary, Hematology,
Renal
1. Hematopoiesis: blood cell
formation Fetus- liver and spleen
Adult- bone marrow
2. Anemia: A condition in which the blood is deficient in red blood cells, in hemoglobin, or in total
volume.
3. Erythropoiesis: formation of red blood
cells In kidney in response to hypoxia
4. macrocytic normochromic anemia: Large RBC's, normal
hemoglobin Folic acid or Vitamin B12 deficiency
5. microcytic hypochromic anemia: small, abnormally shaped erythrocytes that are not
able to carry normal hemoglobin
Thalassemia- mediterranean
6. normocytic normochromic anemia: Characterized by red cells that are relatively
normal in size and normal hemoglobin
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, Aplastic, hemorrhagic, hemolytic, sickle cell
7. iron deficiency anemia: anemia resulting when there is not enough iron to build
hemoglobin for red blood cells
Attects children, poverty, child bearing age
8. Erythrocytes: red
blood cells Most abundant cell
in the body Responsible for
tissue oxygenation Mitotic
division- 100-120 days
9. sickle cell anemia: A genetic disorder in which erythroctyes take on an abnormal curved or
"sickle" shape (Hb-s)
10. Thalassemia: Inherited defect in the ability to produce hemoglobin, usually seen in
persons of Mediter- ranean background.
11. pernicious anemia: Lack of mature erythrocytes caused by inability to absorb
vitamin B12 into the bloodstream
12. hemolytic anemia: Characterized by an inadequate number of circulating red
blood cells due to the premature destruction of red blood cells by the spleen
Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt)
13. Erythropoietin (EPO): Hormone secreted by the kidney to stimulate the production of
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15
Cardiac, Pulmonary, Hematology,
Renal
1. Hematopoiesis: blood cell
formation Fetus- liver and spleen
Adult- bone marrow
2. Anemia: A condition in which the blood is deficient in red blood cells, in hemoglobin, or in total
volume.
3. Erythropoiesis: formation of red blood
cells In kidney in response to hypoxia
4. macrocytic normochromic anemia: Large RBC's, normal
hemoglobin Folic acid or Vitamin B12 deficiency
5. microcytic hypochromic anemia: small, abnormally shaped erythrocytes that are not
able to carry normal hemoglobin
Thalassemia- mediterranean
6. normocytic normochromic anemia: Characterized by red cells that are relatively
normal in size and normal hemoglobin
1/
15
, Aplastic, hemorrhagic, hemolytic, sickle cell
7. iron deficiency anemia: anemia resulting when there is not enough iron to build
hemoglobin for red blood cells
Attects children, poverty, child bearing age
8. Erythrocytes: red
blood cells Most abundant cell
in the body Responsible for
tissue oxygenation Mitotic
division- 100-120 days
9. sickle cell anemia: A genetic disorder in which erythroctyes take on an abnormal curved or
"sickle" shape (Hb-s)
10. Thalassemia: Inherited defect in the ability to produce hemoglobin, usually seen in
persons of Mediter- ranean background.
11. pernicious anemia: Lack of mature erythrocytes caused by inability to absorb
vitamin B12 into the bloodstream
12. hemolytic anemia: Characterized by an inadequate number of circulating red
blood cells due to the premature destruction of red blood cells by the spleen
Pancytopenia- reduction in all 3 types of blood cells (RBC, WBC, Plt)
13. Erythropoietin (EPO): Hormone secreted by the kidney to stimulate the production of
2/
15
