1
Test Bank For Clayton’s Basic Pharmacology
for Nurses 19th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and
Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed
by the FDA. The brand name, or trademark, is the name
given to a drug by its manufacturer. The nonproprietary, or
generic, name is provided by the United States Adopted
Names Council.
Chapter 01: Drug Definitions, Standards, and Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
DIF: Cognitive Level: Knowledge REF: p. 9
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
Environment TOP: Nursing Process Step: Assessment CON:
Patient Education
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 2
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS : C
United States Pharmacopoeia/National Formulary contains information specific to
nutritional supplements. USP Dictionary of USAN & International Drug Names is a
compilation of drug names, pronunciation guide, and possible future FDA approved
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
Database contains evidence - based information on herbal medicines and herbal
combination products; it does not include information specific to nutritional
supplements. Drug Interaction Facts contains comprehensive information on drug
interaction facts; it does not include nutritional
supplements.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
3. Which drug reference contains drug monographs that describe all drugs in a
therapeutic class? a. Drug Facts and Comparisons
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale —The Complete Drug Reference
ANS : A
Drug Facts and Comparisons contains drug monographs that describe all
drugs in a therapeutic class. Monographs are formatted as tables to allow
comparison of similar products, brand names, manufacturers, cost indices,
and available dosage forms Online version is available.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
, 3
4. Which drug reference contains monographs about virtually every single - entity drug
available in the United States and describes therapeutic uses of drugs, including
approved and unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
ANS : B
AHFS Drug Information contains monographs about virtually every single - entity
drug available in the United States and describes therapeutic uses of drugs,
including approved and unapproved uses.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public
a standard, comprehensive, up - to- date look up and downloadable resource about
medicines? a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Drug Reference
ANS : C
DailyMed makes available to healthcare providers and the public a standard,
comprehensive, up - to- date look up and downloadable resource about medicines.
The American Drug Index is not appropriate for patient use. The American Hospital
Formulary is not appropriate for patient use. The drug reference is not appropriate
for patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its
marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS : A
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 4
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
the safety of all drugs before marketing. Later amendments and acts helped tighten
FDA control and ensure drug safety. The Durham Humphrey Amendment defines the
kinds of drugs that cannot be used safely without medical supervision and restricts
their sale to prescription by a licensed practitioner. The Controlled Substances Act
addresses only controlled substances and their categorization. The Kefauver Harris
Drug Amendment ens ures drug efficacy and greater drug safety. Drug
manufacturers are required to prove to the FDA the effectiveness of their products
before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
7. Which classification does meperidine (Demerol) fall under? a. I
b. II
c. III
d. IV
ANS : B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
lead to severe psychological and physical dependence. Schedule I drugs have high
potential for abuse and no recognized medical use. Schedule III drugs have some
potential for abuse. Use may lead to low to moderate physical dependence or high
psychological dependence. Schedule IV drugs have low potential for abuse. Use may
lead to limited physical or psychological dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and
approval for an outbreak of smallpox?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS : D
Once the Investigational New Drug Application has been approved, the drug can
receive highest priority within the agency, which is called fast tracking. A smallpox
outbreak would become a priority concern in the world. Orphan diseases are not
researched in a priority manner. Preclinical research is not omitted. Extending any
phase of the research would mean a longer time to develop a vaccine. The FDA must
ensure that all phases of the preclinical and clinical research phase have been
completed in a safe man ner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
Test Bank For Clayton’s Basic Pharmacology
for Nurses 19th Edition
MULTIPLE CHOICE
1. Which name identifies a drug listed by the US Food and
Drug Administration (FDA)?
a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C
The official name is the name under which a drug is listed
by the FDA. The brand name, or trademark, is the name
given to a drug by its manufacturer. The nonproprietary, or
generic, name is provided by the United States Adopted
Names Council.
Chapter 01: Drug Definitions, Standards, and Information Sources
Willihnganz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
DIF: Cognitive Level: Knowledge REF: p. 9
OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective Care
Environment TOP: Nursing Process Step: Assessment CON:
Patient Education
,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 2
2. Which source contains information specific to nutritional supplements?
a. USP Dictionary of USAN & International Drug Names
b. Natural Medicines Comprehensive Database
c. United States Pharmacopoeia/National Formulary (USP NF)
d. Drug Interaction Facts
ANS : C
United States Pharmacopoeia/National Formulary contains information specific to
nutritional supplements. USP Dictionary of USAN & International Drug Names is a
compilation of drug names, pronunciation guide, and possible future FDA approved
drugs; it does not include nutritional supplements. Natural Medicines Comprehensive
Database contains evidence - based information on herbal medicines and herbal
combination products; it does not include information specific to nutritional
supplements. Drug Interaction Facts contains comprehensive information on drug
interaction facts; it does not include nutritional
supplements.
DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
3. Which drug reference contains drug monographs that describe all drugs in a
therapeutic class? a. Drug Facts and Comparisons
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
b. Drug Interaction Facts
c. Handbook on Injectable Drugs
d. Martindale —The Complete Drug Reference
ANS : A
Drug Facts and Comparisons contains drug monographs that describe all
drugs in a therapeutic class. Monographs are formatted as tables to allow
comparison of similar products, brand names, manufacturers, cost indices,
and available dosage forms Online version is available.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
, 3
4. Which drug reference contains monographs about virtually every single - entity drug
available in the United States and describes therapeutic uses of drugs, including
approved and unapproved uses?
a. Martindale: The Complete Drug Reference
b. AHFS Drug Information
c. Drug Reference
d. Drug Facts and Comparisons
ANS : B
AHFS Drug Information contains monographs about virtually every single - entity
drug available in the United States and describes therapeutic uses of drugs,
including approved and unapproved uses.
DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2
OBJ: 3 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Planning CON: Safety | Patient Education | Clinical Judgment
5. Which online drug reference makes available to healthcare providers and the public
a standard, comprehensive, up - to- date look up and downloadable resource about
medicines? a. American Drug Index
b. American Hospital Formulary
c. DailyMed
d. Drug Reference
ANS : C
DailyMed makes available to healthcare providers and the public a standard,
comprehensive, up - to- date look up and downloadable resource about medicines.
The American Drug Index is not appropriate for patient use. The American Hospital
Formulary is not appropriate for patient use. The drug reference is not appropriate
for patient use.
DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 OBJ: 3
NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Implementation
CON: Safety | Patient Education | Clinical Judgment
6. Which legislation authorizes the FDA to determine the safety of a drug before its
marketing?
a. Federal Food, Drug, and Cosmetic Act (1938)
b. Durham Humphrey Amendment (1952)
Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition
c. Controlled Substances Act (1970)
d. Kefauver Harris Drug Amendment (1962)
ANS : A
, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Edition 4
The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine
the safety of all drugs before marketing. Later amendments and acts helped tighten
FDA control and ensure drug safety. The Durham Humphrey Amendment defines the
kinds of drugs that cannot be used safely without medical supervision and restricts
their sale to prescription by a licensed practitioner. The Controlled Substances Act
addresses only controlled substances and their categorization. The Kefauver Harris
Drug Amendment ens ures drug efficacy and greater drug safety. Drug
manufacturers are required to prove to the FDA the effectiveness of their products
before marketing them.
DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3
OBJ: 5 NAT: NCLEX Client Needs Category: Physiological Integrity
TOP: Nursing Process Step: Assessment
CON: Safety | Patient Education | Evidence | Health Care Law
7. Which classification does meperidine (Demerol) fall under? a. I
b. II
c. III
d. IV
ANS : B
Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may
lead to severe psychological and physical dependence. Schedule I drugs have high
potential for abuse and no recognized medical use. Schedule III drugs have some
potential for abuse. Use may lead to low to moderate physical dependence or high
psychological dependence. Schedule IV drugs have low potential for abuse. Use may
lead to limited physical or psychological dependence.
DIF: Cognitive Level: Knowledge REF: p. 10 OBJ: 2
NAT: NCLEX Client Needs Category: Safe, Effective Care Environment
TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
8. Which action would the FDA take to expedite drug development and
approval for an outbreak of smallpox?
a. List smallpox as a health orphan disease.
b. Omit the preclinical research phase.
c. Extend the clinical research phase.
d. Fast track the investigational drug.
ANS : D
Once the Investigational New Drug Application has been approved, the drug can
receive highest priority within the agency, which is called fast tracking. A smallpox
outbreak would become a priority concern in the world. Orphan diseases are not
researched in a priority manner. Preclinical research is not omitted. Extending any
phase of the research would mean a longer time to develop a vaccine. The FDA must
ensure that all phases of the preclinical and clinical research phase have been
completed in a safe man ner.
DIF: Cognitive Level: Knowledge REF: p. 7 OBJ: 5
