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NR 293 Pharm Exam 1 Chamberlain Questions and Verified Solutions. Graded A+

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NR 293 Pharm Exam 1 Chamberlain Questions and Verified Solutions. Graded A+

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NR 293 Pharm Exam 1 Chamberlain
Questions and Verified Solutions.
Graded A+
QUESTIONS AND ANSWERS


Risks for injury. ANSWER - know that anything can be a possible risk for patient injury

9 rights of medicine administration. ANSWER - right patient, right dose, right medication,
right time, right documentation, right route, right reason, right response

what is a prototype. ANSWER - the first drug of a class that all others are based from (ex-
morphine)

what is pharmacokinetics. ANSWER - what the body does to the drug

what is pharmacodynamics. ANSWER - what the drug does to the body

bioavailability. ANSWER - what portion of the drug that entered the circulation can have
an effect on the body

first pass effect. ANSWER - a drug enters the GI tract and is filtered to the liver where
some is destroyed

what enzymes work in the liver. ANSWER - P-450 enzymes

if a patient has cirrhosis of the liver, what will happen when they take a medication?.
ANSWER - When the medication passes through the liver for the first pass, there will be
less P-450 enzymes so the bioavailability of the medication will be higher and it will
circulate in the bloodstream longer.

half life. ANSWER - time required for 50% of the drug to be removed from the body

Pharmacotherapeutics. ANSWER - treatment of conditions

enteral route. ANSWER - through the GI tract

parenteral tract. ANSWER - outside the GI tract

,how is medication absorption different for neonates and children?. ANSWER - they have
less gastric acid to break down medications and availability is higher

why do more drugs enter neonate and children's brains, why are meds not as easily
excreted/destroyed by liver and kidneys ?. ANSWER - immature BBB, liver, and kidneys

Polypharmacy. ANSWER - The use of multiple medications on a regular basis

during which phase of the nursing process does a nurse prioritize the nursing diagnoses?.
ANSWER - planning

the nurse recognizes that drugs given by which route will be altered by the first pass effect?
a. oral
b. sublingual
c. subcutaneous
d. IV
e. rectal. ANSWER - oral and rectal

the nurse is reviewing a list of a patient's medications and notes one of the drugs has a low
therapeutic index. what does this mean?. ANSWER - the difference between a therapeutic
dose and a toxic dose are very close together

when drug A is an enzyme inhibitor of drug B, the nurse will anticipate what result of drug
B?. ANSWER - level of drug B could rise to toxicity

A drug is highly protein bound, what does this mean?. ANSWER - it will have a longer
duration of action

do no harm is what ethical principle?. ANSWER - nonmaleficence

Which legal act required drug manufacturers to establish the safety and efficacy of a new
drug before its approval for use?. ANSWER - Kefauver-Harris, amendment of 1962

over the counter drugs (otc) are. ANSWER - nonprescription drugs that are used for short
term treatment

what herbal supplement is used to promote sleep and relaxation, prolonged use can cause
yellow discoloration of nails, risk for liver toxicity. ANSWER - kava

herbal supplement used to decrease nausea and vomiting induced by chemotherapy.
ANSWER - ginkgo

which drug classes are used as OTC remedies ?
a. NSAIDs
b. cold remedies

, c. antibiotics
d.smoking deterrent drugs
e. antihypertensive drugs
f. histamine 2 (H2) blockers. ANSWER - A, B,D,F

what are side effects of NSAIDs?. ANSWER - stroke, MI, GI ulcers, kidney dysfunction

what do antibiotics do?. ANSWER - fight off infection caused by bacteria

Bacteriostatic. ANSWER - doesn't kill bacteria, it inhibits growth

bactericidal. ANSWER - kills bacteria

healthcare associated infections. ANSWER - are contracted in a hospital or institution
(>48 hours after admin) , are more difficult to treat, and are more virulent

antiseptics. ANSWER - are used for living tissue, inhibit growth of bacteria

disinfectants. ANSWER - used on nonliving tissue, destroy/kill organisms

what is a priority of the nurse to perform before beginning an antibiotic therapy?.
ANSWER - obtain a culture and sensitivity specimen

prophylactic therapy. ANSWER - preventative measure, antibiotics given before a
procedure to ensure that an infection will not start

empiric therapy. ANSWER - treatment of an infection before c+s information has been
obtained or reported

definitive therapy. ANSWER - treatment of a specific infection after receiving repot of c+s

what two classes of antibiotics are common for causing allergic reactions?. ANSWER -
penicillins and sulfonamides

if a person is allergic to penicillin, what other class of antibiotics should be looked into?.
ANSWER - cephalosporins

what is the main example of sulfonamides?. ANSWER - Bactrim

what must Bactrim be taken with?. ANSWER - 2000-3000 mL of H20/ day

what is the MOA of sulfonamides ?. ANSWER - bacteriostatic

Indications for sulfonamides. ANSWER - broad spectrum, gram + or -; UTIs

adverse effects of sulfonamides. ANSWER - SJS, photosensitivity

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