Evolve Pharmacology HESI Exam 2026/2027 – Elsevier
Evolve – Comprehensive NGN-Style
Pharmacotherapeutics Competency Assessment for
RN Licensure Readiness|Just Released!!Proffessor
Verified Exam
A client receives a prescription for theophylline PO to be
initiated in the morning after the dose of theophylline IV is
complete. The nurse determines that a theophylline level
drawn yesterday was 22 mcg/mL. Based on this
information, which action should the nurse implement?
A. Hold the theophylline dose and notify the health care
provider.
B. Start the client on a half-dose of theophylline PO.
,C. The theophylline dose can be initiated as planned.
D. The client is not ready to be weaned from the IV to the
PO route. - ANSWER-A. Hold the theophylline dose and
notify the health care provider.
The therapeutic range for theophylline is 10 to 20 mcg/mL,
so the theophylline dose should be held for fear of causing
toxicity. Options B, C, and D are not indicated actions
based on the reported theophylline level.
A client with acute lymphocytic leukemia is to begin
chemotherapy today. The health care provider's
prescription specifies that ondansetron is to be
administered IV 30 minutes prior to the infusion of
,cisplatin. What is the rationale for administering Zofran
prior to the chemotherapy induction?
A. Promotion of diuresis to prevent nephrotoxicity
B. Reduction or elimination of nausea and vomiting
C. Prevention of a secondary hyperuricemia
D. Reduction in the risk of an allergic reaction - ANSWER-
B. Reduction or elimination of nausea and vomiting
Ondansetron is a type 3 receptor (5-HT3) antagonist that
is recognized for improved control of acute nausea and
vomiting associated with chemotherapy. 5-HT3
antagonists are most effective when administered IV prior
, to the induction of the chemotherapeutic agent(s). Options
A, C, and D are not therapeutic actions of ondansetron.
A client taking linezolid at home for an infected foot ulcer
calls the home care nurse to report the onset of watery
diarrhea. Which intervention should the nurse implement?
A. Schedule appointments to obtain blood samples for
drug peak and trough levels.
B. Reassure the client that this is an expected side effect
that will resolve in a few days.
C. Instruct the client to obtain a stool specimen to be taken
to the laboratory for analysis.
Evolve – Comprehensive NGN-Style
Pharmacotherapeutics Competency Assessment for
RN Licensure Readiness|Just Released!!Proffessor
Verified Exam
A client receives a prescription for theophylline PO to be
initiated in the morning after the dose of theophylline IV is
complete. The nurse determines that a theophylline level
drawn yesterday was 22 mcg/mL. Based on this
information, which action should the nurse implement?
A. Hold the theophylline dose and notify the health care
provider.
B. Start the client on a half-dose of theophylline PO.
,C. The theophylline dose can be initiated as planned.
D. The client is not ready to be weaned from the IV to the
PO route. - ANSWER-A. Hold the theophylline dose and
notify the health care provider.
The therapeutic range for theophylline is 10 to 20 mcg/mL,
so the theophylline dose should be held for fear of causing
toxicity. Options B, C, and D are not indicated actions
based on the reported theophylline level.
A client with acute lymphocytic leukemia is to begin
chemotherapy today. The health care provider's
prescription specifies that ondansetron is to be
administered IV 30 minutes prior to the infusion of
,cisplatin. What is the rationale for administering Zofran
prior to the chemotherapy induction?
A. Promotion of diuresis to prevent nephrotoxicity
B. Reduction or elimination of nausea and vomiting
C. Prevention of a secondary hyperuricemia
D. Reduction in the risk of an allergic reaction - ANSWER-
B. Reduction or elimination of nausea and vomiting
Ondansetron is a type 3 receptor (5-HT3) antagonist that
is recognized for improved control of acute nausea and
vomiting associated with chemotherapy. 5-HT3
antagonists are most effective when administered IV prior
, to the induction of the chemotherapeutic agent(s). Options
A, C, and D are not therapeutic actions of ondansetron.
A client taking linezolid at home for an infected foot ulcer
calls the home care nurse to report the onset of watery
diarrhea. Which intervention should the nurse implement?
A. Schedule appointments to obtain blood samples for
drug peak and trough levels.
B. Reassure the client that this is an expected side effect
that will resolve in a few days.
C. Instruct the client to obtain a stool specimen to be taken
to the laboratory for analysis.
