Immunotherapy Certificate
EXAM 1 QUESTIONS AND
VERIFIED CORRECT
ANSWERS GRADED A+
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What are cytokines? - CORRECT ANSWER-cytokines are secreted by lymphocytes with the
intention of stimulating macrophages and cytotoxic t lymphocytes to identify and kill pathogen
infected cells or tumor cells
What do proto-oncogenes do? - CORRECT ANSWER-regulate normal cell growth and division.
What are proto-oncogenes? - CORRECT ANSWER-they are a large family of genes that code for
proteins and enzymes that turn on the cell cycle
If a mistake in copies of DNA occur next to a porto-oncogene, it can "turn on" and become
what? - CORRECT ANSWER-oncogene
What are two examples of an oncogene? - CORRECT ANSWER-EGFR/Erb- B1 and Erb-B2/HER2
, What is a very important tumor suppressor gene? - CORRECT ANSWER-p53
What is the p53 gene also called? - CORRECT ANSWER-suicide gene
What does neoadjuvant therapy refer to? - CORRECT ANSWER-treatment given as a first step to
shrink a tumor before the main treatment
What is adjuvant therapy? - CORRECT ANSWER-additional cancer treatment given after the
primary treatment to lower the risk that cancer will occur
How do alkylating agents function? - CORRECT ANSWER-by causing a break in the DNA helix
strand, causing interference with DNA replication, which results in cell death
What are the three most common alkylating agent chemo's? - CORRECT ANSWER-cytoxan, ifos,
bendamustine
How are alkylating agents and platinum based chemo's different? - CORRECT ANSWER-platinum
based chemo's do not have the molecule to to attach to and destroy DNA
What are the two most common platinum based chemo's? - CORRECT ANSWER-cisplatin and
carboplatin
What should you instruct patients to do when receiving oxaliplatin? - CORRECT ANSWER-to
avoid exposure to cold air and consuming cold fluids for 3 to 4 days following treatment
What are the two most nephrotoxic drugs? - CORRECT ANSWER-streptozocin and semustine
What are the most common side effects of antimetabolites? - CORRECT ANSWER-
myelosuppresion, GI toxicities, photosensitivity, hand foot syndrome,