ANSWERS 100% CORRECT!!
, Microcytic anemia - ANSWER iron deficiency, usually due to malabsorption / occult
blood loss, or lead poisoning. MCV <80
Normocytic anemia - ANSWER due to hemorrhage or chronic disease. Aplastic anemia.
MVC 80-92
macrocytic anemia - ANSWER due to folate or vitamin B12(cobalamin) deficiency
(megaloblastic anemia) / pernicious anemia. /liver diseases
serum ferritin - ANSWER Tests for iron stores. As serum ferritin falls, TIBC rises, and
serum iron levels will eventually fall.
Anemia of chronic disease - ANSWER NORMOcytic anemia with ↓ serum iron,
↓ TIBC, and normal iron stores. Treat with epoetin and give an iron
supplement
Schistocytes - ANSWER Associated with hemolytic uremia syndrome
pernicious anemia - ANSWER Macrocytic anemia caused by vitamin B12 deficiency.
B12 is essential to maturation of erythrocytes - low levels will cause the RBC to expand.
PPIs and histamine2 blockers can cause this.
Increased homocysteine & methylmalonic acid level indicates ? - ANSWER B12
deficiency
increased homocysteine levels - ANSWER Folate deficiency
Sperocytes - ANSWER Appear as spheres, lack central pallor, smaller diameter,
indicate immune-mediated process - can be seen after blood transfusion
aplastic anemia - ANSWER a normocytic anemia characterized by the failure of bone
marrow to produce red blood cells
Low ferritin - ANSWER iron deficiency anemia
Transferrin - ANSWER transports iron