AQUIFER CASE STUDY vc vc
Exam Solution vc
Internal Medicine Exam Cartes 2026 A+ GRADE ASSURE vc vc vc vc vc vc vc
D COMPLETE SOLUTIONS AND VERIFIED ANSWERS (C79
vc vc vc vc vc vc
51)
QUESTION 1 vc
A 24-year-
vc
old woman presents with complaints of excessive thirst over the past several weeks. She
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
also notes waking up in the middle of the night to urinate. She recently underwent trans
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
sphenoidal resection of a pituitary adenoma. Which of the following is the most likely di
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
agnosis?
A. Central diabetes insipidus
vc vc vc
B. Nephrogenic diabetes insipidus
vc vc vc
C. Primary polydipsia
vc vc
D. Type 2 diabetes mellitus
vc vc vc vc
ANSWER
A. Central diabetes insipidus Central diabetes insipidus is the most common type of diabetes insipidus, i
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
s associated with deficient secretion of antidiuretic hormone (ADH) by the posterior pituitary.
vc vc vc vc vc vc vc vc vc vc vc vc
QUESTION 2 vc
What is the most common presenting symptom of bladder carcinoma?
vc vc vc vc vc vc vc vc vc
A. Nocturia
vc
B. Painless hematuria
vc vc
C. Unintentional weight loss
vc vc vc
D. Urinary frequency
vc vc
ANSWER
B. Painless hematuria The primary modality to diagnose bladder cancer is with cystoscopy, which allow
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
s for direct visualization of tissues and biopsy of any abnormalities. Smoking is the most important risk
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
factor of bladder cancer. vc vc vc
QUESTION 3 vc
,A 25-year-
vc
old man presents to the clinic with fever and a sore throat. A throat swab is performed a
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
nd the culture comes back positive for group A streptococcus bacteria. What system of hi
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
s body is at highest risk for permanent damage if proper treatment for his infection is no
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
t administered?
vc
A. Cardiovascular
vc
B. Gastrointestinal
vc
C. Musculoskeletal
vc
D. Pulmonary
vc
ANSWER
A. Cardiovascular Risk of rheumatic fever and pericarditis. Remember the Jones criteria for rheumatic fe
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ver: Major: Joints, carditis, nodes, erythema marginatum, sydenham chorea. Minor: fever, arthralgia, elev
vc vc vc vc vc vc vc vc vc vc vc vc
ated ESR, elevated CRP, and prolonged PR interval. Need 2 major, or 1 major and 2 minor, or 3 minor
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
QUESTION 4 vc
Which of the following best describes the etiology of the jaundice seen in patients with t
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
hyroid storm? vc
A. Direct constricting effects of thyroid hormone on the biliary duct
vc vc vc vc vc vc vc vc vc vc
B. Hepatic tissue hypoxia due to increased peripheral consumption of oxygen
vc vc vc vc vc vc vc vc vc vc
C. Hypotension leading to decreased gut motility
vc vc vc vc vc vc
D. Impaired reabsorption of thyroid hormone in the enterohepatic circulation
vc vc vc vc vc vc vc vc vc
ANSWER
B. Hepatic tissue hypoxia due to increased peripheral consumption of oxygen. Signs and symptoms of th
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
yroid storm include hyperpyrexia, nausea, vomiting, diarrhea, mental status changes, jaundice, high-
vc vc vc vc vc vc vc vc vc vc vc
output congestive heart failure, cardiac tachyarrhythmias, hypertension, and diaphoresis. PE will show g
vc vc vc vc vc vc vc vc vc vc vc vc
oiter, lid lag, hand tremor, and warm, moist skin Labs will show low TSH and high free T4 or T3 Most c
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ommonly caused by an acute event Treatment is: 1) beta blocker (propranolol) 2) thionamide (propylth
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
iouracil or methimazole) 3) iodine solution 4) glucocorticoids
vc vc vc vc vc vc vc
QUESTION 5 vc
Which of the following is associated with aortic stenosis?
vc vc vc vc vc vc vc vc
A. de Musset sign
vc vc vc
B. Holodiastolic decrescendo murmur
vc vc vc
C. Syncope
vc
D. Wide pulse pressure
vc vc vc
ANSWER
C. Syncope Patient will be older With a history of diabetes, hypertension Complaining of dyspnea, chest
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
pain, syncope PE will show crescendo-
vc vc vc vc vc
decrescendo systolic murmur that radiates to the carotids, paradoxically split S2, S4 gallop Most commo
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
nly caused by degenerative calcification Treatment is aortic valve replacement Comments: murmur decr
vc vc vc vc vc vc vc vc vc vc vc vc
eases with Valsalva vc vc
, QUESTION 6 vc
Which of the following conditions is most commonly associated with malar or "butterfly"
vc vc vc vc vc vc vc vc vc vc vc vc v
rash?
c
A. Parvovirus B19 infection
vc vc vc
B. Pregnancy
vc
C. Rosaceavc
D. Systemic lupus erythematosus
vc vc vc
ANSWER
D. Systemic lupus erythematosus Systemic lupus erythematosus is most commonly seen in African-
vc vc vc vc vc vc vc vc vc vc vc vc
American patients of childbearing age. Antinuclear antibodies (ANA) is the best initial screening test (m
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ost sensitive but not specific). The presence of either anti-double-stranded DNA (dsDNA) and anti-
vc vc vc vc vc vc vc vc vc vc vc vc vc
smith (anti- vc
SM) antibodies is diagnostic of SLE (very specific but not sensitive). Treatment is NSAIDs, steroids, imm
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
unosuppressants, hydroxychloroquine Drug- vc vc
induced: Hydralazine, INH, Procainamide, Phenytoin, Sulfonamides (HIPPS). False-
vc vc vc vc vc vc vc
positive test for syphilis vc vc vc
QUESTION 7 vc
A 44-year-old man presents for a follow-
vc vc vc vc vc vc
up visit for his known gastroesophageal reflux disease. He has been taking a histamine-
vc vc vc vc vc vc vc vc vc vc vc vc vc
2-
receptor antagonist twice a day. He continues to have symptoms at least three times per
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
week. Which of the following is the next best therapy?
vc vc vc vc vc vc vc vc vc
A. Calcium carbonate
vc vc
B. Famotidine
vc
C. Omeprazole
vc
D. Sucralfate vc
ANSWER
C. Omeprazole Proton pump inhibitors (PPIs), such as omeprazole, should be used in patients who fail t
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
wice-daily histamine-2- vc
receptor antagonist therapy, in patients with erosive esophagitis, or patients with severe and frequent s
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ymptoms of gastroesophageal reflux disease (GERD). PPIs inhibit gastric acid secretions by irreversibly
vc vc vc vc vc vc vc vc vc vc vc vc vc
binding and inhibiting the hydrogen- vc vc vc vc
potassium ATPase pump. They should be taken 30 minutes before the first meal of the day. Treatment i
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
s weight loss, elevation head of bed during sleep, avoidance of certain foods (caffeine, alcohol, acidic foo
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ds)
QUESTION 8 vc
Which of the following laboratory values is most likely to be elevated in a patient with h
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ypertonic hyponatremia? vc
Exam Solution vc
Internal Medicine Exam Cartes 2026 A+ GRADE ASSURE vc vc vc vc vc vc vc
D COMPLETE SOLUTIONS AND VERIFIED ANSWERS (C79
vc vc vc vc vc vc
51)
QUESTION 1 vc
A 24-year-
vc
old woman presents with complaints of excessive thirst over the past several weeks. She
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
also notes waking up in the middle of the night to urinate. She recently underwent trans
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
sphenoidal resection of a pituitary adenoma. Which of the following is the most likely di
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
agnosis?
A. Central diabetes insipidus
vc vc vc
B. Nephrogenic diabetes insipidus
vc vc vc
C. Primary polydipsia
vc vc
D. Type 2 diabetes mellitus
vc vc vc vc
ANSWER
A. Central diabetes insipidus Central diabetes insipidus is the most common type of diabetes insipidus, i
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
s associated with deficient secretion of antidiuretic hormone (ADH) by the posterior pituitary.
vc vc vc vc vc vc vc vc vc vc vc vc
QUESTION 2 vc
What is the most common presenting symptom of bladder carcinoma?
vc vc vc vc vc vc vc vc vc
A. Nocturia
vc
B. Painless hematuria
vc vc
C. Unintentional weight loss
vc vc vc
D. Urinary frequency
vc vc
ANSWER
B. Painless hematuria The primary modality to diagnose bladder cancer is with cystoscopy, which allow
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
s for direct visualization of tissues and biopsy of any abnormalities. Smoking is the most important risk
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
factor of bladder cancer. vc vc vc
QUESTION 3 vc
,A 25-year-
vc
old man presents to the clinic with fever and a sore throat. A throat swab is performed a
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
nd the culture comes back positive for group A streptococcus bacteria. What system of hi
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
s body is at highest risk for permanent damage if proper treatment for his infection is no
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
t administered?
vc
A. Cardiovascular
vc
B. Gastrointestinal
vc
C. Musculoskeletal
vc
D. Pulmonary
vc
ANSWER
A. Cardiovascular Risk of rheumatic fever and pericarditis. Remember the Jones criteria for rheumatic fe
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ver: Major: Joints, carditis, nodes, erythema marginatum, sydenham chorea. Minor: fever, arthralgia, elev
vc vc vc vc vc vc vc vc vc vc vc vc
ated ESR, elevated CRP, and prolonged PR interval. Need 2 major, or 1 major and 2 minor, or 3 minor
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
QUESTION 4 vc
Which of the following best describes the etiology of the jaundice seen in patients with t
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
hyroid storm? vc
A. Direct constricting effects of thyroid hormone on the biliary duct
vc vc vc vc vc vc vc vc vc vc
B. Hepatic tissue hypoxia due to increased peripheral consumption of oxygen
vc vc vc vc vc vc vc vc vc vc
C. Hypotension leading to decreased gut motility
vc vc vc vc vc vc
D. Impaired reabsorption of thyroid hormone in the enterohepatic circulation
vc vc vc vc vc vc vc vc vc
ANSWER
B. Hepatic tissue hypoxia due to increased peripheral consumption of oxygen. Signs and symptoms of th
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
yroid storm include hyperpyrexia, nausea, vomiting, diarrhea, mental status changes, jaundice, high-
vc vc vc vc vc vc vc vc vc vc vc
output congestive heart failure, cardiac tachyarrhythmias, hypertension, and diaphoresis. PE will show g
vc vc vc vc vc vc vc vc vc vc vc vc
oiter, lid lag, hand tremor, and warm, moist skin Labs will show low TSH and high free T4 or T3 Most c
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ommonly caused by an acute event Treatment is: 1) beta blocker (propranolol) 2) thionamide (propylth
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
iouracil or methimazole) 3) iodine solution 4) glucocorticoids
vc vc vc vc vc vc vc
QUESTION 5 vc
Which of the following is associated with aortic stenosis?
vc vc vc vc vc vc vc vc
A. de Musset sign
vc vc vc
B. Holodiastolic decrescendo murmur
vc vc vc
C. Syncope
vc
D. Wide pulse pressure
vc vc vc
ANSWER
C. Syncope Patient will be older With a history of diabetes, hypertension Complaining of dyspnea, chest
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
pain, syncope PE will show crescendo-
vc vc vc vc vc
decrescendo systolic murmur that radiates to the carotids, paradoxically split S2, S4 gallop Most commo
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
nly caused by degenerative calcification Treatment is aortic valve replacement Comments: murmur decr
vc vc vc vc vc vc vc vc vc vc vc vc
eases with Valsalva vc vc
, QUESTION 6 vc
Which of the following conditions is most commonly associated with malar or "butterfly"
vc vc vc vc vc vc vc vc vc vc vc vc v
rash?
c
A. Parvovirus B19 infection
vc vc vc
B. Pregnancy
vc
C. Rosaceavc
D. Systemic lupus erythematosus
vc vc vc
ANSWER
D. Systemic lupus erythematosus Systemic lupus erythematosus is most commonly seen in African-
vc vc vc vc vc vc vc vc vc vc vc vc
American patients of childbearing age. Antinuclear antibodies (ANA) is the best initial screening test (m
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ost sensitive but not specific). The presence of either anti-double-stranded DNA (dsDNA) and anti-
vc vc vc vc vc vc vc vc vc vc vc vc vc
smith (anti- vc
SM) antibodies is diagnostic of SLE (very specific but not sensitive). Treatment is NSAIDs, steroids, imm
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
unosuppressants, hydroxychloroquine Drug- vc vc
induced: Hydralazine, INH, Procainamide, Phenytoin, Sulfonamides (HIPPS). False-
vc vc vc vc vc vc vc
positive test for syphilis vc vc vc
QUESTION 7 vc
A 44-year-old man presents for a follow-
vc vc vc vc vc vc
up visit for his known gastroesophageal reflux disease. He has been taking a histamine-
vc vc vc vc vc vc vc vc vc vc vc vc vc
2-
receptor antagonist twice a day. He continues to have symptoms at least three times per
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
week. Which of the following is the next best therapy?
vc vc vc vc vc vc vc vc vc
A. Calcium carbonate
vc vc
B. Famotidine
vc
C. Omeprazole
vc
D. Sucralfate vc
ANSWER
C. Omeprazole Proton pump inhibitors (PPIs), such as omeprazole, should be used in patients who fail t
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
wice-daily histamine-2- vc
receptor antagonist therapy, in patients with erosive esophagitis, or patients with severe and frequent s
vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ymptoms of gastroesophageal reflux disease (GERD). PPIs inhibit gastric acid secretions by irreversibly
vc vc vc vc vc vc vc vc vc vc vc vc vc
binding and inhibiting the hydrogen- vc vc vc vc
potassium ATPase pump. They should be taken 30 minutes before the first meal of the day. Treatment i
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
s weight loss, elevation head of bed during sleep, avoidance of certain foods (caffeine, alcohol, acidic foo
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ds)
QUESTION 8 vc
Which of the following laboratory values is most likely to be elevated in a patient with h
vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc vc
ypertonic hyponatremia? vc