EVALUATION ACCURATE QUESTIONS
GRADED A PLUS
●● Protein features.
Answer: active site, motif, domain, binding site
●● Uniprot.
Answer: integrates, Universal Protein Resource, protein sequence &
function, worlds most comprehensive info on proteins, domains
• Swissprot & TrEMBL
• PIR Protein information Resource
●● Uniprot KB.
Answer: funct, class, cross-ref, well annotated, all protein products from
gene in species
●● UniParc.
Answer: sources, history, all p sequences, sequences 100% alike merged
w/o regarding species, link back to KB and parc
●● UniRef.
, Answer: combines similar sequences
●● Proteomes.
Answer: protein sets from fully sequenced genomes
●● Interpro.
Answer: Integrated resource of PF Domains & Sites an integrated
database of protein families, domains, motifs and functional sites.
o 2nd protein database
o Identifying distant relationships in sequences, predicting funct. &
struct.
o Don't share nomenclature & format
o Integrated top layer, Unique & nonredundant characterization of pf,
domain, funct. Site
o Has cross-ref to BLOCKS & others
●● Blocks.
Answer: multiply aligned ungapped segments for the most highly
conserved regions of proteins
●● motif.
Answer: a server that scans databases to find motifs or patterns and that
can generate sequence profiles.