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Samenvatting Cel III: Hoofdstuk 3

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2025/2026 Written for academic year
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Universiteit Gent (UGent)
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Cel III: Energie en metabolisme
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Dit is een samenvatting van het derde hoofdstuk van cel III voor 1ste bachelor tandheelkunde & geneeskunde (samen les) aan de UGent. Het bevat alle leerstof van de powerpoints en mijn notities van de lessen van Jan Gettemans. Met deze samenvatting heb ik een 18/20 gehaald, dus veel succes!

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De krebscyclus
→ matrix vd mitochondriën
De totale reactie
1)​ Aldolcondensatie
-​ citryl-CoA = onstabiel DUS CoA komt los ⇒ citroenzuur/citraat → symmetrie
-​ tertiair alcohol = moeilijk → oxideren DUS secundair maken (2de stap)




2)​ Dehydratatie & hydratatie
-​ mbv aconitase
-​ HIERNA WEL oxideren
3)​ Oxidatie
-​ NAD+ W NADH
-​ mbv isocitraat dehydrogenase
-​ geeft (instabiel) beta-ketocarbonzuur
4)​ Spontane decarboxylering
-​ geeft alfa-ketoglutaarzuur




5)​ Decarboxylering & binding CoA
-​ mbv alfa-ketoglutaraat dehydrogenase
-​ geeft succinyl-CoA = OOK voor andere zaken
-​ BV heemring = succinyl-CoA & AZ Glycine
-​ R- SCoA ⇒ gebruiken → GTP/ATP te maken ⇒ geeft succinaat
6)​ Oxidatie
-​ mbv succinaat dehydrogenase
-​ geeft fumaarzuur
-​ FAD W FADH2

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Tandheelkunde
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  • tandheelkunde
  • geneeskunde
  • cel 3
  • ugent

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