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CMSRN 2025 Sample Questions & Answers with Rationales – Medical-Surgical RN Certification Exam Prep

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Prepare for success on the Certified Medical-Surgical Registered Nurse (CMSRN) exam with this comprehensive collection of 2025 sample questions designed to strengthen your clinical knowledge and test-taking skills. This resource includes high-quality, exam-style questions covering key medical-surgical topics such as cardiovascular, respiratory, neurological, gastrointestinal, and endocrine disorders, along with detailed answer explanations to reinforce understanding. Ideal for nurses preparing for certification, this guide provides realistic practice to help you build confidence, identify weak areas, and improve performance. Perfect for quick review or in-depth study, it is an essential tool for passing the CMSRN exam.

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CMSRN 2026 Sample
Questions & Answers
with Rationales –
Medical-Surgical RN
Certification Exam Prep
Review | Graded A+ |
Guaranteed success|



Updated 2026 Questions and Answers

100% Verified Exam Prep and Comprehensive
Rationales
Included

,The nurse receives all of the following stat orders for Rationale: The nurse should questions the order for Lovenox because the
Mr. Palmer. Which one should the nurse question? patient is receiving a heparin drip.
1) Oxygen per nasal cannula at 4 L per minute.
2) Enoxaparin (Lovenox) 40 mg subcutaneously.
3) Troponin level.
4) Computed tomography (CT) angiogram.


Christine Warren, 45 years old, has a long history of 1) The stoma appears pale and dry.
ulcerative colitis, and non-surgical treatment no longer
relieved her symptoms. She underwent a total Rationale: If there is an adequate blood supply to the stoma, the color is pink
proctocolectomy and a permanent ileostomy 12 hours or red, and the stoma is moist as a result of mucous production. A pale dry
ago. color suggests ischemia of the stoma or bowel and must be reported
The nurse should contact the physician immediately if immediately to the physician. With an ileostomy initially after surgery, the output
Mrs. Warren has which of these findings? is a loose, dark green liquid that may contain some blood. The ileostomy
usually begins to drain within 24 of surgery at more than one liter per day.
1) The stoma appears pale and dry.
2) The stoma appears red and shiny.
3) There is 200 mL of dark green output from the stoma.
4) There is 50 mL of serosanguinous drainage from the
stoma.


When changing Mrs. Warren's ileostomy bag, the nurse 3) Use a solid skin barrier.
notices that the peristomal skin is irritated.
Rationale: The drainage from the stoma can quickly irritate the surrounding
Which of these actions by the nurse would be tissue. Therefore, a solid skin barrier, with a pectin base or karaya wafer that has
appropriate before reapplying the appliance? a measurable thickness and hydrocolloid adhesive properties, should be
1) Wash the area with antiseptic soap and water. applied.
2) Clean the site with Dakin's solution.
3) Use a solid skin barrier.
4) Obtain an order for a topical antibiotic.

, Which of these comments, if made by Mrs. Warren 3) "I need to go shopping for some loose, baggy clothes."
before her surgery, would indicate that she had
concerns about her body image? Rationale:Body image refers to a person's perception of self and determines
how the person interacts with others. One does not need to purchase special
1) "I will have to stop my aerobics classes." clothing after ileostomy surgery, although some minor adjustments may be
2) "I'm so afraid I may not survive the surgery." needed for comfort, e.g., stretch underwear or pantyhose for support.
3) "I need to go shopping for some loose, baggy
clothes."
4) "I'm concerned that this may be only the first of many
surgeries."


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Lewis Palmer, 45 years old, has a history of multiple 4) check the femoral puncture site at frequent intervals.
myocardial infarctions and is a heavy smoker. He takes Rationale: Since bleeding is a common side effect of heparin, it is vital to check
warfarin sodium (Coumadin) daily. Two weeks ago, he the operative site, the femoral puncture area, for signs of bleeding.
had a right femoral-popliteal bypass, which became
occluded 24 hours ago. He is admitted following an
angioplasty of the femoral-popliteal bypass graft. Mr.
Palmer is receiving continuous IV heparin.


Because Mr. Palmer is receiving heparin, it is essential
for the nurse to
1) monitor his prothrombin time.
2) observe him for signs of pulmonary embolism.
3) limit his intake of foods high in vitamin K.
4) check the femoral puncture site at frequent intervals.

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