Rated A
1. Figure Animations: Regulation of Hor- Hormonal Stimuli
mone Release 1. Involves tropic hormones
2. The most common type of stimul us for hor-
Comparing the three Types of Stimuli mone release by the major endocrine glands
for Hormone Release. Drag and drop 3. Hormone release caused by another hor-
each phrase below into the correct cat- mone
egory. 4. Terminated by negative feedback by a hor-
mone.
5. Example: Leutinizing hormone causes testos-
terone release
Humoral Stimuli
1. Example: rising potassium levels caus e al-
dosterone release
2. Terminated by negative feedback by he reg-
ulated substance
3. Hormone released caused by altere d levels
of certain critical ions or nutrients
Neural stimuli
1. Hormone release caused by neural input
2. Not terminated by negative feedback
3. Example: Stress causes corticotropin releas-
ing hormone (CRH) release from the hypothal-
amus
2. Hormone Release by Hormonal Stimuli-
Place each choice in its correct position
on the image.
,UNIT 3: Endocrine System (Mylab and Mastering) Test with Answers
Rated A
3. Jeremy has been feeling tired and cold Both TSH and TRH would be lower than normal
for the last week. His roommate of-
fers Jeremy his bottle of thyroid hor- (Thyroid hormone release follows the pattern
mone supplements and promises that of a hormonal stimulus for hormone release.
they will make him feel better (they When thyroid hormone levels go up, there is
don't). Suppose that Jeremy's thyroid increased negative feedback on both TRH from
hormone levels were normal to start the hypothalamus and TSH from the anterior
with, and that the supplements ac- pituitary, so blood levels of these hormones
tually did contain active thyroid hor- decrease.)
mones. After taking these supplements
for a week, how do you think Jeremy's
blood levels of thyroid-stimulating hor-
mone (TSH) and thyrotropin-releasing
hormone (TRH) would compare to nor-
mal levels?
4. Cortisol is a hormone that was not
mentioned in the video. It helps the
body deal with stressors and is released
from the adrenal cortex in response
to hormonal stimuli. Using your knowl-
edge of how the hormonal stimulus pat-
tern works, drag and drop the follow-
ing words into the location that makes
sense for them. Not all choices will be
used.
,5. Glucose levels in the blood are tight- (1) humoral
ly controlled. An important hormone
for controlling blood glucose is insulin, (2) Falls
which is released by the pancreas. In-
(3) Negative
creases in blood glucose cause insulin
release. This is an example of a hor- (Glucose is a critical nutrient in the blood. Its
mone released in response to a (1) blood levels directly control release of the hor-
stimulus. Insulin release is ter- mone insulin from the pancreas, so this is an
minated when blood glucose (2) .
example of a humoral stimulus for hormone
This is an example of (3) feed-
release. In this case, a rise in blood glucose
back.
levels causes insulin release, and a fall in blood
glucose terminates insulin release. This is an
example of negative feedback.)
6. Both high blood glucose levels and low
blood glucose levels are stimuli that
trigger specific responses by the body.
These responses cause blood glucose
levels to return to their set point. In this
activity, you will explore how this hap-
pens.To review how the body regulates
blood sugar levels
Regulating blood sugar
This diagram shows how the body keeps
blood glucose at a normal level.
Drag each label to the appropriate loca-
tion on the diagram.
7. Events of Second Messenger Cyclic AMP
Signaling Mechanism
, Most water-soluble hormones exert
their effects through the second mes-
senger cyclic AMP (cAMP). This activi-
ty will test your understanding of the
events that occur during cAMP signal-
ing.
Drag the events of cAMP signaling in the
correct sequence from left to right.
8. Which of the following enzymes are im- phosphodiesterase
portant in the deactivation of cAMP and
termination of signaling? (The increase in cAMP levels is usually
short-lived because the enzyme phosphodi-
A. phosphodiesterase esterase is constantly present in the cytoplasm
B. protein kinase of the target cells.)
C. G protein
D. adenylate cyclase
9. The amplification of the signal from cAMP in the cytoplasm
a water-soluble hormone is achieved
through an increase in (Many cAMP can be generated as a second
messenger to amplify the signal in response to
hormone binding.)
10. Water-soluble hormones affect target plasma membrane receptors
cells by binding to
(Water-soluble hormones bind to specific re-
ceptors in the plasma membrane, whereas
steroid hormones bind to cytoplasmic recep-
tors.)
11.