UNIVERSITY 2026 STUDY GUIDE
TEST PAPER QUESTIONS AND
SOLUTIONS GRADED A+
◉ Cushing's syndrome result from an excess of:
A. Lutenizing hormone
B. Follicle stimulating hormone
C. Cortisol
D. Aldosterone. Answer: C. Cortisol
◉ What causes most cases of Cushing's syndrome. Answer: Pituitary
adenomas
◉ What is the most common cause of Cushing's syndrome. Answer:
Pituitary tumor
◉ What is the most common cause of ACTH-independent cases of
Cushing's syndrome?
A. A pituitary tumors
B. An adrenal tumor
C. Phepchromocytoma
D. Iatrogenic causes resulting from therapeutic doses of synthetic
glucocorticoids. Answer: D. Iatrogenic causes resulting from therapeutic
doses of synthetic glucocorticoids
,◉ Cushing's disease is the specific type of Cushing's syndrome that is
caused by:
A. Long-term exposure to corticosteroids
B. A benign tumor in the adrenal gland
C. A benign pituitary tumor
D. An ectopic tumor that produces ACTH. Answer: C. A benign
pituitary tumor
◉ Which of the following serum laboratory findings are present in the
client with Cushing's syndrome?
A. Increased cortisol, decreased sodium, and decreased potassium levels
B. Decreased cortisol, decreased potassium, and decreased glucose
levels
C. Increased cortisol, increased sodium, decreased potassium levels
D. Normal blood urea nitrogen, increased sodium, and decreased
potassium levels.. Answer: C. Increased cortisol, increased sodium, and
decreased potassium levels
◉ Janice has had Cushing's disease for 20 years and has been taking
hydrocortisone since then. Today, she appears with a think trunk and
thin extremities. She has a "moon face" a "buffalo hump" think skin with
visible capillaries, and a number of bruises that pear to be slow healing.
To what do you attribute these symptoms?
A. Decreased adrenal androgen glands
B. Malfunctioning of the adrenal cortex
C. Excessive levels of circulating cortisol
, D. Ectopic secretion of adrenocorticotropic hormone.. Answer: C.
Excessive levels of circulating cortisol
◉ First line approach to tx Cushing's syndrome in a 56yo woman who
has been taking oral corticosteroids to tx rheumatoid arthritis for the past
2 years.
A. Gradually tapering corticosteroid use
B. Referral for surgery
C. Consider radiation tx
D. Prescribe mifepristone. Answer: A. Gradually tapering corticosteroid
use
◉ Untreated Cushing's syndrome can lead to all of the following
EXCEPT:
A. Rheumatoid arthritis
B. Hypertension
C. Type 2 diabetes
D. Osteoporosis. Answer: A. Rheumatoid arthritis
◉ The most commonly recommended treatment for Cushing's disease is:
A. Tapering or ceasing corticosteroid use
B. Eliminating trigger medications
C. Antineoplastic tx
D. Surgical intervention. Answer: D. Surgical intervention