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ATI Pharmacology Exam (Set 3) — 50 Questions with Multiple Answers & Rationale
1. A nurse is preparing to administer digoxin 0.125 mg PO. The client’s apical pulse is
52 bpm. Which action should the nurse take?
• A. Administer the medication as ordered
• B. Hold the dose and notify the healthcare provider
• C. Give half the dose and recheck pulse in 30 minutes
• D. Repeat the apical pulse in 1 hour
☑ ☑ correct answers ☑ : B. Hold the dose and notify the healthcare provider
Rationale: The general guideline is to hold digoxin for an apical pulse <60 bpm in
adults (or <70 in infants/children) unless otherwise specified. Bradycardia increases
the risk of digoxin toxicity and further heart block.
2. A client is receiving a continuous IV heparin infusion. Which laboratory value
indicates the therapy is therapeutic?
• A. INR 2.5
• B. aPTT 65 seconds (control 30 seconds)
• C. Platelets 150,000/mm³
, • D. Bleeding time 8 minutes
☑ ☑ correct answers ☑ : B. aPTT 65 seconds (control 30 seconds)
Rationale: Therapeutic aPTT for heparin is 1.5–2.5 times the normal control (45–75
sec). INR is for warfarin. Platelets monitor for HIT, not therapeutic effect.
3. A nurse is teaching a client about warfarin. Which statement by the client indicates a
need for further teaching?
• A. "I will use a soft toothbrush."
• B. "I can eat salads every day as long as the amount is consistent."
• C. "I will take ibuprofen for my headaches."
• D. "I will get my INR checked regularly."
☑ ☑ correct answers ☑ : C. "I will take ibuprofen for my headaches."
Rationale: NSAIDs like ibuprofen increase bleeding risk when combined with warfarin.
Acetaminophen is safer but still monitor INR. Consistent vitamin K intake (salads) is
acceptable if kept steady.
4. A client is prescribed furosemide 40 mg IV push. Which finding requires the nurse to
hold the dose?
• A. Blood pressure 150/90 mmHg
• B. Serum potassium 3.2 mEq/L
• C. Weight gain of 1 kg in 24 hours
• D. Urine output 30 mL/hour
, ☑ ☑ correct answers ☑ : B. Serum potassium 3.2 mEq/L
Rationale: Furosemide is a loop diuretic that causes potassium wasting. Hypokalemia
(normal 3.5–5.0) increases risk of arrhythmias, especially if the patient is on digoxin.
Hold and notify provider.
5. A client is taking metformin for type 2 diabetes. Which instruction should the nurse
include?
• A. "Take this medication with food to reduce GI upset."
• B. "Skip your dose if you are having a CT scan with contrast."
• C. "You may drink alcohol in moderation."
• D. "Monitor for weight gain as a common side effect."
☑ ☑ correct answers ☑ : A. Take this medication with food to reduce GI upset
Rationale: Metformin commonly causes nausea, diarrhea, and abdominal discomfort;
taking with meals reduces these effects. It should be held 48 hours before and after IV
contrast to prevent lactic acidosis. Alcohol increases lactic acidosis risk.
6. A nurse is administering IV potassium chloride. Which action is unsafe?
• A. Diluting potassium in 100 mL NS
• B. Infusing via IV pump at 10 mEq/hour
• C. Giving undiluted potassium as a slow IV push
• D. Adding potassium to an empty IV bag before filling
☑ ☑ correct answers ☑ : C. Giving undiluted potassium as a slow IV push
Rationale: IV push potassium can cause immediate cardiac arrest. Potassium must