Table of Contents
Table of Contents 1
Chapter 01- Introduction to Drugs 3
Chapter 02- Drugs and the Body 20
Chapter 03- Toxic Effects of Drugs 37
Chapter 04- The Nursing Process in Drug Therapy and Patient Safety 54
Chapter 05- Dosage Calculations 71
Chapter 06- Challenges to Effective Drug Therapy 86
Chapter 07- Introduction to Cell Physiology 103
Chapter 08- Anti-infective Agents 120
Chapter 09- Antibiotics 138
Chapter 10- Antiviral Agents 155
Chapter 11- Antifungal Agents 172
Chapter 12- Antiprotozoal Agents 188
Chapter 13- Anthelmintic Agents 204
Chapter 14- Antineoplastic Agents 220
Chapter 15- Introduction to the Immune Response and Inflammation 237
Chapter 16- Anti-inflammatory, Antiarthritis, and Related Agents 254
Chapter 17- Immune Modulators 270
Chapter 18- Vaccines and Sera 287
Chapter 19- Introduction to Nerves and the Nervous System 304
Chapter 20- Anxiolytic and Hypnotic Agents 320
Chapter 21- Antidepressant Agents 337
Chapter 22- Psychotherapeutic Agents 354
Chapter 23- Antiseizure Agents 371
Chapter 24- Antiparkinsonism Agents 388
Chapter 25- Muscle Relaxants 404
Chapter 26- Narcotics, Narcotic Antagonists, and Antimigraine Agents 420
Chapter 27- General and Local Anesthetic Agents 436
Chapter 28- Neuromuscular Junction Blocking Agents 453
Chapter 29- Introduction to the Autonomic Nervous System 470
Chapter 30- Adrenergic Agonists 487
Chapter 31- Adrenergic Antagonists 503
Chapter 32- Cholinergic Agonists 520
Chapter 33- Anticholinergic Agents 536
Chapter 34- Introduction to the Endocrine System 553
Chapter 35- Hypothalamic and Pituitary Agents 569
Chapter 36- Adrenocortical Agents 585
Chapter 37- Thyroid and Parathyroid Agents 602
Chapter 38- Agents to Control Blood Glucose Levels 619
Chapter 39- Introduction to the Reproductive System 636
Chapter 40- Drugs Affecting the Female Reproductive System 653
Chapter 41- Drugs Affecting the Male Reproductive System 669
Chapter 42- Introduction to the Cardiovascular System 685
Chapter 43- Drugs Affecting Blood Pressure 702
Chapter 44- Agents for Treating Heart Failure 719
Chapter 45- Antiarrhythmic Agents 735
Chapter 46- Antianginal Agents 752
Chapter 47- Lipid-Lowering Agents 768
Chapter 48- Drugs Affecting Blood Coagulation 785
Chapter 49- Drugs Used to Treat Anemias 801
Chapter 50- Introduction to the Renal System 817
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Chapter 51- Diuretic Agents 833
Chapter 52- Drugs Affecting the Urinary Tract and the Bladder 849
Chapter 53- Introduction to the Respiratory System 866
Chapter 54- Drugs Acting on the Upper Respiratory Tract 883
Chapter 55- Drugs Acting on the Lower Respiratory Tract 900
Chapter 56- Introduction to the Gastrointestinal System 917
Chapter 57- Drugs Affecting Gastrointestinal Secretions 933
Chapter 58- Drugs Affecting Gastrointestinal Motility 949
Chapter 59- Antiemetic Agents 965
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Chapter 01- Introduction to Drugs
1. A nurse /working /in /radiology /administers /iodine /to /a /patient / who /is /having /a / computed /tomography
/(CT) /scan. /The /nurse / working / on /the /oncology / unit /administers / chemotherapy /to /patients /who /have
/cancer. / At /the /Public /Health /Department, /a /nurse /administers / a /measles-mumps-rubella /(MMR)
/vaccine /to /a /14-month-old /child /as /a /routine /immunization. /Which /branch /of /pharmacology / best
/describes /the / actions /of /all /three /nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology /is /the /study / of /the /biologic /effects /of /chemicals. /Nurses / are /involved /with /clinical
/pharmacology / or /pharmacotherapeutics, /which /is /a /branch /of /pharmacology /that /deals /with /the /uses /of
/drugs /to /treat, /prevent, /and /diagnose /disease. /The /radiology /nurse /is /administering /a /drug /to /help
/diagnose /a /disease. /The /oncology /nurse /is /administering /a /drug /to /help /treat /a /disease.
Pharmacoeconomics /includes /any / costs /involved /in /drug /therapy. /Pharmacodynamics /involves /how / a
/drug / affects /the /body / and /pharmacokinetics /is /how /the /body / acts /on /the /body.
2. A /physician /has /ordered /intramuscular /(IM) /injections /of /morphine, /a /narcotic, /every /4 / hours /as /needed
/for /pain /in / a /motor /vehicle /accident /victim. /The /nurse /is /aware /this /drug / has /a /high / abuse /potential.
/ Under /what /category / would /morphine /be /classified?
A) Schedule / I
B) Schedule / II
C) Schedule / III
D) Schedule / IV
Ans: B
Feedback:
Narcotics / with / a / high / abuse / potential / are / classified / as / Schedule / II / drugs / because / of / severe / dependence
, Test Bank - Focus on Nursing Pharmacology (7th Edition by Amy Karch) 4
liability. /Schedule /I /drugs /have /high / abuse /potential /and /no /accepted / medical /use. /Schedule /III /drugs
/have /a /lesser /abuse /potential /than /II /and /an /accepted /medical /use. /Schedule /IV /drugs /have /low /abuse
/potential /and /limited /dependence /liability.
3. When / involved / in / phase / III / drug / evaluation / studies, / what / responsibilities / would / the / nurse / have?
A) Working / with / animals / who / are / given / experimental / drugs
B) Choosing / appropriate / patients / to / be / involved / in / the / drug / study
C) Monitoring / and / observing / patients / closely / for / adverse / effects
D) Conducting /research /to /determine /effectiveness /of /the /drug
/ Ans: C
Feedback:
Phase /III /studies /involve /use /of / a /drug /in /a /vast /clinical /population /in / which /patients /are /asked /to /record
/any / symptoms / they / experience / while / taking / the / drugs. / Nurses / may / be / responsible / for / helping
/ collect /and / analyze /the /information /to /be /shared / with /the /Food /and /Drug / Administration /(FDA) /but
/would /not / conduct /research /independently / because /nurses /do /not /prescribe /medications. /Use /of /animals /in
/drug /testing / is / done / in / the / preclinical / trials. / Select / patients / who / are / involved / in / phase / II / studies / to
/ participate /in /studies /where /the /participants /have /the /disease /the /drug /is /intended /to /treat. /These /patients
/are / monitored /closely / for /drug / action / and /adverse /effects. /Phase /I /studies /involve /healthy /human
/volunteers / who /are /usually /paid /for /their /participation. /Nurses /may / observe /for / adverse /effects /and
/toxicity.
4. What / concept / is / considered / when / generic / drugs / are / substituted / for / brand / name / drugs?
A) Bioavailability
B) Critical / concentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability /is /the /portion /of / a /dose /of /a /drug /that /reaches /the /systemic /circulation /and /is /available /to
/act /on /body / cells. /Binders /used /in /a / generic /drug /may / not /be /the /same / as /those /used /in /the /brand /name
/drug. /Therefore, /the / way /the /body / breaks /down /and /uses /the /drug / may /differ, /which /may /eliminate / a
/generic /drug /substitution. /Critical /concentration /is /the /amount /of /a /drug /that /is /needed /to /cause /a
/therapeutic / effect / and / should / not / differ / between / generic / and / brand / name / medications.
/ Distribution / is /the / phase / of / pharmacokinetics, / which / involves / the / movement / of / a / drug / to / the
/ body’s / tissues / and / is / the