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PHARM HESI 1 EXAM| LATEST 2026/2027| ALL 54 REAL QUESTIONS AND CORRECT ANSWERS SELECTED FROM PAST PAPERS EXAMS| GUARANTEED PASS (BRAND NEW!!)

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PHARM HESI Exam Study Guide 2025 – 54 Practice Questions & Answers for Nursing Students Prepare for the HESI Pharmacology Exam with this comprehensive, real-exam-based study guide. Featuring 54 actual practice questions and answers, this document covers critical nursing pharmacology topics including medication side effects, patient teaching, lab value monitoring, drug interactions, and priority nursing actions. Perfect for nursing students seeking to pass the HESI or NCLEX on the first attempt. PHARM HESI 1 EXAM| LATEST 2026/2027| ALL 54 REAL QUESTIONS AND CORRECT ANSWERS SELECTED FROM PAST PAPERS EXAMS| GUARANTEED PASS (BRAND NEW!!) 1. A client complaints about upset stomach when taking Resedronate. What will the nurse ask the client? - ANSWER️-How does she take the medication 2. How does the nurse know that Kayexalate is effective? - ANSWER️-K+ 3.8 3. The nurse is administering IV fluconazole (Diflucan) to a client who has systemic candidiasis. After reviewing the diagnostic studies, the nurse identifies a rising trend in the liver enzyme for aspartate aminotransferase (AST). What action should the nurse implement? - ANSWER️-Hold the dose and notify the healthcare provider of the changes in laboratory studies 4. The nurse suspects that a client has experienced an adverse response to a prescribed medications. What action should the nurse take first? - ANSWER️-Complete a focused systems assessment of the client 5. A male client who has been taking a high-dose of an NSAID comes to the clinic complaining of gastric pain and blood in his stool. The healthcare provider discontinues the NSAIDs and prescribes esomeprazole (Nexium). Which information should the nurse include in this client's teaching plan? - ANSWER️-Notify the healthcare provider of the passage of black stools 6. The nurse assesses a client with intermittent claudication who is receiving pentoxifylline (Trental). Which assessment should the nurse perform to determine the effectiveness of the medication? - ANSWER️-Monitor numeric pain scale. 7. A female client is receiving rifampin (Rifadin), an antitubercular medication. Which assessment by this client should prompt the nurse to notify the prescriber of a potential problem? - ANSWER️-Reports sclera are yellow. 8. The nurse administers naloxone to a client with opioid-induced respiratory depression. One hour later, nursing assessment reveals that the client has a respiratory rate of 4 breaths/min, SpaO2 of 75%, and is unable to be aroused. What action should the nurse implement? - ANSWER️-Administer a second dose of naloxone 9. A client is receiving orlistat (Xenical) as part of a weight management program. Which ongoing assessment should be included in the plan of care to determine the effectiveness of the medication? - ANSWER️-BMI 10. A male client with Laennec's cirrhosis refuses to take the daily dose of lactulose because he had three soft stools yesterday. Which action should the nurse implement? - ANSWER️-Explain that this effect reduces serum ammonia levels. 11. Prior to administering morning medications, the nurse assesses a client who is receiving digoxin (Lanoxin) 0.25mg PO, levothyroxine (Synthroid) 0.5mcg PO, and Olmesartan hydrochlorothiazide (Benicar HCT) 40/12.5 PO. Which assessment finding indicates that the nurse should withhold one of the morning medication doses? - ANSWER️-Apical pulse of 52bpm 12. A client receiving filgrastim (Neupogen) reports increasing bone pain. What action should the nurse implement? - ANSWER️-Administer a prescribed PRN analgesic 13. A Schiz patient on Risperidone making funny body movements...? - ANSWER️-Give Benzo tropine 14. A client is taking Isotretinoin for acne. What should the nurse advise? - ANSWER️-Consider a different job other than a lifeguard 15. A client is giving himself a self-injection with Epi-pen. The nurse should intervene if - ANSWER️-Client cleans the Epi-pen for reuse 16. A male client who is currently receiving methadone (Dolophine) 10mg q8hrs reports that his pain is an 8 on a scale of 1 to 10. Which action should the nurse implement? - ANSWER️-Give the PRN dose of Morphine for break-through pain 17. A wife is caring for her husband who has Parkinson’s disease. The wife calls the clinic and report the husband has involuntary movement... - ANSWER️-Determine what other medications the patient has taken 18. What are some common side effects of antidepressants? - ANSWER️-Blurred vision, dry ,mouth, constipation 19. A client is discharged with a prescription for warfarin. What discharge instructions should the nurse emphasize? - ANSWER️-Avoid going barefoot especially outside 20. A client who is taking an oral dose of tetracycline complains of GI upset. What snack should the nurse instruct the client to take with this medication? - ANSWER️-Toasted wheat bread and jelly 21. A patient was given a dose of Trimethobenzamide is sedated but easily aroused. What should the nurse do? - ANSWER️-Allow the patient to rest 22. A client is having an acute asthma attack. What medication to administer? - ANSWER️-Pirbuterol 23. The nurse is assessing the client’s INR which is 20. What is the nurse's priority? - ANSWER️-Give Vitamin K 24. A client is being educated on Benadryl. What is the most important teaching? - ANSWER️-Avoid driving

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PHARM HESI 1 EXAM|
LATEST 2026/2027| ALL 54 REAL
QUESTIONS AND CORRECT
ANSWERS SELECTED FROM
PAST PAPERS EXAMS|
GUARANTEED PASS (BRAND
NEW!!)
1. A client complaints about upset stomach when taking Resedronate. What
will the nurse ask the client? - ANSWER✔️-How does she take the
medication

2. How does the nurse know that Kayexalate is effective? - ANSWER✔️-K+
3.8


3. The nurse is administering IV fluconazole (Diflucan) to a client who has
systemic candidiasis. After reviewing the diagnostic studies, the nurse
identifies a rising trend in the liver enzyme for aspartate aminotransferase
(AST). What action should the nurse implement? - ANSWER✔️-Hold the
dose and notify the healthcare provider of the changes in laboratory studies

4. The nurse suspects that a client has experienced an adverse response to a
prescribed medications. What action should the nurse take first? -
ANSWER✔️-Complete a focused systems assessment of the client

5. A male client who has been taking a high-dose of an NSAID comes to the
clinic complaining of gastric pain and blood in his stool. The healthcare
provider discontinues the NSAIDs and prescribes esomeprazole (Nexium).
Which information should the nurse include in this client's teaching plan? -
ANSWER✔️-Notify the healthcare provider of the passage of black stools

, 6. The nurse assesses a client with intermittent claudication who is receiving
pentoxifylline (Trental). Which assessment should the nurse perform to
determine the effectiveness of the medication? - ANSWER✔️-Monitor
numeric pain scale.

7. A female client is receiving rifampin (Rifadin), an antitubercular medication.
Which assessment by this client should prompt the nurse to notify the
prescriber of a potential problem? - ANSWER✔️-Reports sclera are yellow.

8. The nurse administers naloxone to a client with opioid-induced respiratory
depression. One hour later, nursing assessment reveals that the client has a
respiratory rate of 4 breaths/min, SpaO2 of 75%, and is unable to be
aroused. What action should the nurse implement? - ANSWER✔️-
Administer a second dose of naloxone

9. A client is receiving orlistat (Xenical) as part of a weight management
program. Which ongoing assessment should be included in the plan of care
to determine the effectiveness of the medication? - ANSWER✔️-BMI

10.A male client with Laennec's cirrhosis refuses to take the daily dose of
lactulose because he had three soft stools yesterday. Which action should the
nurse implement? - ANSWER✔️-Explain that this effect reduces serum
ammonia levels.

11.Prior to administering morning medications, the nurse assesses a client who
is receiving digoxin (Lanoxin) 0.25mg PO, levothyroxine (Synthroid)
0.5mcg PO, and Olmesartan hydrochlorothiazide (Benicar HCT) 40/12.5
PO. Which assessment finding indicates that the nurse should withhold one
of the morning medication doses? - ANSWER✔️-Apical pulse of 52bpm

12.A client receiving filgrastim (Neupogen) reports increasing bone pain. What
action should the nurse implement? - ANSWER✔️-Administer a prescribed
PRN analgesic

13.A Schiz patient on Risperidone making funny body movements...? -
ANSWER✔️-Give Benzo tropine

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