AP® Advanced Placement Biology Instructor’s
AP® Advanced Solution
Placement
Manual
Biology
ch 1-38.pdf
Instructor’s Solution Manual ch 1-38.pdf 3/31/2026, 11:46:21 AM
SOLUTION MANUAL
ADVANCED PLACEMENT BIOLOGY
AP® Biology Instructor Solution Manual Part 1&2
Table of Contents – Part 1
1 | The Study of Life .............................................................................................................. 1
Review Questions ......................................................................................................................................................1
Critical Thinking Questions ........................................................................................................................................4
Test Prep for AP® Courses .........................................................................................................................................6
2 | The Chemical Foundation of Life ....................................................................................... 9
Review Questions ......................................................................................................................................................9
Critical Thinking Questions ......................................................................................................................................14
Test Prep for AP® Courses .......................................................................................................................................18
Science Practice Challenge Questions .....................................................................................................................20
3 | Biological Macromolecules ............................................................................................. 25
Review Questions ....................................................................................................................................................25
Critical Thinking Questions ......................................................................................................................................34
Test Prep for AP® Courses .......................................................................................................................................41
Science Practice Challenge Questions .....................................................................................................................48
4 | Cell Structure ................................................................................................................. 59
Review Questions ....................................................................................................................................................59
Critical Thinking Questions ......................................................................................................................................66
Advanced Placement Biology Instructor’s Solution Manual
Copyright 2025, Rice University. All Rights Reserved. This ancillary resource is intended for instructor use only and
may not be uploaded, redistributed, or reproduced without written approval by OpenStax.
3/31/2026, 11:46:16 AM AP® Advanced Placement Biology Instructor’s
AP® Advanced
Solution
Placement
Manual ch
Biology
1-38.pdf
Instructor’s Solution Manual ch 1-38
,AP® Advanced Placement Biology Instructor’s
AP® Advanced Solution
Placement
Manual
Biology
ch 1-38.pdf
Instructor’s Solution Manual ch 1-38.pdf 3/31/2026, 11:46:21 AM
ii Table of Contents – Part 1
Test Prep for AP® Courses .......................................................................................................................................72
Science Practice Challenge Questions .....................................................................................................................77
5 | Structure and Function of Plasma Membranes ............................................................... 86
Review Questions ....................................................................................................................................................86
Critical Thinking Questions ......................................................................................................................................90
Test Prep for AP® Courses .......................................................................................................................................96
Science Practice Challenge Questions ...................................................................................................................101
6 | Metabolism ................................................................................................................. 106
Review Questions ..................................................................................................................................................106
Critical Thinking Questions ....................................................................................................................................115
Test Prep for AP® Courses .....................................................................................................................................122
Science Practice Challenge Questions ...................................................................................................................126
7 | Cellular Respiration ...................................................................................................... 137
Review Questions ..................................................................................................................................................137
Critical Thinking Questions ....................................................................................................................................144
Test Prep for AP® Courses .....................................................................................................................................150
Science Practice Challenge Questions ...................................................................................................................156
8 | Photosynthesis............................................................................................................. 164
Review Questions ..................................................................................................................................................164
Critical Thinking Questions ....................................................................................................................................169
Test Prep for AP® Courses .....................................................................................................................................174
Science Practice Challenge Questions ...................................................................................................................180
9 | Cell Communication ..................................................................................................... 187
Review Questions ..................................................................................................................................................187
Critical Thinking Questions ....................................................................................................................................192
Advanced Placement Biology Instructor’s Solution Manual
Copyright 2025, Rice University. All Rights Reserved. This ancillary resource is intended for instructor use only and
may not be uploaded, redistributed, or reproduced without written approval by OpenStax.
3/31/2026, 11:46:16 AM AP® Advanced Placement Biology Instructor’s
AP® Advanced
Solution
Placement
Manual ch
Biology
1-38.pdf
Instructor’s Solution Manual ch 1-38
,AP® Advanced Placement Biology Instructor’s
AP® Advanced Solution
Placement
Manual
Biology
ch 1-38.pdf
Instructor’s Solution Manual ch 1-38.pdf 3/31/2026, 11:46:21 AM
Test Prep for AP® Courses .....................................................................................................................................198
Science Practice Challenge Questions ...................................................................................................................202
10 | Cell Reproduction ....................................................................................................... 209
Review Questions ..................................................................................................................................................209
Critical Thinking Questions ....................................................................................................................................214
Advanced Placement Biology Instructor’s Solution Manual
Copyright 2025, Rice University. All Rights Reserved. This ancillary resource is intended for instructor use only and
may not be uploaded, redistributed, or reproduced without written approval by OpenStax.
3/31/2026, 11:46:16 AM AP® Advanced Placement Biology Instructor’s
AP® Advanced
Solution
Placement
Manual ch
Biology
1-38.pdf
Instructor’s Solution Manual ch 1-38
, AP® Advanced Placement Biology Instructor’s
AP® Advanced Solution
Placement
Manual
Biology
ch 1-38.pdf
Instructor’s Solution Manual ch 1-38.pdf 3/31/2026, 11:46:21 AM
iv Table of Contents – Part 1
Test Prep for AP® Courses .....................................................................................................................................218
Science Practice Challenge Questions ...................................................................................................................226
11 | Meiosis and Sexual Reproduction ............................................................................... 230
Review Questions ..................................................................................................................................................230
Critical Thinking Questions ....................................................................................................................................233
Test Prep for AP® Courses .....................................................................................................................................238
Science Practice Challenge Questions .........................................................................................................................
12 | Mendel's Experiments and Heredity ........................................................................... 241
Review Questions ..................................................................................................................................................241
Critical Thinking Questions ....................................................................................................................................247
Test Prep for AP® Courses .....................................................................................................................................250
Science Practice Challenge Questions ...................................................................................................................255
13| Modern Understandings of Inheritance ....................................................................... 266
Review Questions ..................................................................................................................................................266
Critical Thinking Questions ....................................................................................................................................269
Test Prep for AP® Courses .....................................................................................................................................271
Science Practice Challenge Questions ...................................................................................................................276
14 | DNA Structure and Function ....................................................................................... 281
Review Questions ..................................................................................................................................................281
Critical Thinking Questions ....................................................................................................................................291
Test Prep for AP® Courses .....................................................................................................................................303
Science Practice Challenge Questions ...................................................................................................................312
15 | Genes and Proteins .................................................................................................... 320
Review Questions ..................................................................................................................................................320
Critical Thinking Questions ....................................................................................................................................326
Advanced Placement Biology Instructor’s Solution Manual
Copyright 2025, Rice University. All Rights Reserved. This ancillary resource is intended for instructor use only and
may not be uploaded, redistributed, or reproduced without written approval by OpenStax.
3/31/2026, 11:46:16 AM AP® Advanced Placement Biology Instructor’s
AP® Advanced
Solution
Placement
Manual ch
Biology
1-38.pdf
Instructor’s Solution Manual ch 1-38
AP® Advanced Solution
Placement
Manual
Biology
ch 1-38.pdf
Instructor’s Solution Manual ch 1-38.pdf 3/31/2026, 11:46:21 AM
SOLUTION MANUAL
ADVANCED PLACEMENT BIOLOGY
AP® Biology Instructor Solution Manual Part 1&2
Table of Contents – Part 1
1 | The Study of Life .............................................................................................................. 1
Review Questions ......................................................................................................................................................1
Critical Thinking Questions ........................................................................................................................................4
Test Prep for AP® Courses .........................................................................................................................................6
2 | The Chemical Foundation of Life ....................................................................................... 9
Review Questions ......................................................................................................................................................9
Critical Thinking Questions ......................................................................................................................................14
Test Prep for AP® Courses .......................................................................................................................................18
Science Practice Challenge Questions .....................................................................................................................20
3 | Biological Macromolecules ............................................................................................. 25
Review Questions ....................................................................................................................................................25
Critical Thinking Questions ......................................................................................................................................34
Test Prep for AP® Courses .......................................................................................................................................41
Science Practice Challenge Questions .....................................................................................................................48
4 | Cell Structure ................................................................................................................. 59
Review Questions ....................................................................................................................................................59
Critical Thinking Questions ......................................................................................................................................66
Advanced Placement Biology Instructor’s Solution Manual
Copyright 2025, Rice University. All Rights Reserved. This ancillary resource is intended for instructor use only and
may not be uploaded, redistributed, or reproduced without written approval by OpenStax.
3/31/2026, 11:46:16 AM AP® Advanced Placement Biology Instructor’s
AP® Advanced
Solution
Placement
Manual ch
Biology
1-38.pdf
Instructor’s Solution Manual ch 1-38
,AP® Advanced Placement Biology Instructor’s
AP® Advanced Solution
Placement
Manual
Biology
ch 1-38.pdf
Instructor’s Solution Manual ch 1-38.pdf 3/31/2026, 11:46:21 AM
ii Table of Contents – Part 1
Test Prep for AP® Courses .......................................................................................................................................72
Science Practice Challenge Questions .....................................................................................................................77
5 | Structure and Function of Plasma Membranes ............................................................... 86
Review Questions ....................................................................................................................................................86
Critical Thinking Questions ......................................................................................................................................90
Test Prep for AP® Courses .......................................................................................................................................96
Science Practice Challenge Questions ...................................................................................................................101
6 | Metabolism ................................................................................................................. 106
Review Questions ..................................................................................................................................................106
Critical Thinking Questions ....................................................................................................................................115
Test Prep for AP® Courses .....................................................................................................................................122
Science Practice Challenge Questions ...................................................................................................................126
7 | Cellular Respiration ...................................................................................................... 137
Review Questions ..................................................................................................................................................137
Critical Thinking Questions ....................................................................................................................................144
Test Prep for AP® Courses .....................................................................................................................................150
Science Practice Challenge Questions ...................................................................................................................156
8 | Photosynthesis............................................................................................................. 164
Review Questions ..................................................................................................................................................164
Critical Thinking Questions ....................................................................................................................................169
Test Prep for AP® Courses .....................................................................................................................................174
Science Practice Challenge Questions ...................................................................................................................180
9 | Cell Communication ..................................................................................................... 187
Review Questions ..................................................................................................................................................187
Critical Thinking Questions ....................................................................................................................................192
Advanced Placement Biology Instructor’s Solution Manual
Copyright 2025, Rice University. All Rights Reserved. This ancillary resource is intended for instructor use only and
may not be uploaded, redistributed, or reproduced without written approval by OpenStax.
3/31/2026, 11:46:16 AM AP® Advanced Placement Biology Instructor’s
AP® Advanced
Solution
Placement
Manual ch
Biology
1-38.pdf
Instructor’s Solution Manual ch 1-38
,AP® Advanced Placement Biology Instructor’s
AP® Advanced Solution
Placement
Manual
Biology
ch 1-38.pdf
Instructor’s Solution Manual ch 1-38.pdf 3/31/2026, 11:46:21 AM
Test Prep for AP® Courses .....................................................................................................................................198
Science Practice Challenge Questions ...................................................................................................................202
10 | Cell Reproduction ....................................................................................................... 209
Review Questions ..................................................................................................................................................209
Critical Thinking Questions ....................................................................................................................................214
Advanced Placement Biology Instructor’s Solution Manual
Copyright 2025, Rice University. All Rights Reserved. This ancillary resource is intended for instructor use only and
may not be uploaded, redistributed, or reproduced without written approval by OpenStax.
3/31/2026, 11:46:16 AM AP® Advanced Placement Biology Instructor’s
AP® Advanced
Solution
Placement
Manual ch
Biology
1-38.pdf
Instructor’s Solution Manual ch 1-38
, AP® Advanced Placement Biology Instructor’s
AP® Advanced Solution
Placement
Manual
Biology
ch 1-38.pdf
Instructor’s Solution Manual ch 1-38.pdf 3/31/2026, 11:46:21 AM
iv Table of Contents – Part 1
Test Prep for AP® Courses .....................................................................................................................................218
Science Practice Challenge Questions ...................................................................................................................226
11 | Meiosis and Sexual Reproduction ............................................................................... 230
Review Questions ..................................................................................................................................................230
Critical Thinking Questions ....................................................................................................................................233
Test Prep for AP® Courses .....................................................................................................................................238
Science Practice Challenge Questions .........................................................................................................................
12 | Mendel's Experiments and Heredity ........................................................................... 241
Review Questions ..................................................................................................................................................241
Critical Thinking Questions ....................................................................................................................................247
Test Prep for AP® Courses .....................................................................................................................................250
Science Practice Challenge Questions ...................................................................................................................255
13| Modern Understandings of Inheritance ....................................................................... 266
Review Questions ..................................................................................................................................................266
Critical Thinking Questions ....................................................................................................................................269
Test Prep for AP® Courses .....................................................................................................................................271
Science Practice Challenge Questions ...................................................................................................................276
14 | DNA Structure and Function ....................................................................................... 281
Review Questions ..................................................................................................................................................281
Critical Thinking Questions ....................................................................................................................................291
Test Prep for AP® Courses .....................................................................................................................................303
Science Practice Challenge Questions ...................................................................................................................312
15 | Genes and Proteins .................................................................................................... 320
Review Questions ..................................................................................................................................................320
Critical Thinking Questions ....................................................................................................................................326
Advanced Placement Biology Instructor’s Solution Manual
Copyright 2025, Rice University. All Rights Reserved. This ancillary resource is intended for instructor use only and
may not be uploaded, redistributed, or reproduced without written approval by OpenStax.
3/31/2026, 11:46:16 AM AP® Advanced Placement Biology Instructor’s
AP® Advanced
Solution
Placement
Manual ch
Biology
1-38.pdf
Instructor’s Solution Manual ch 1-38
