MMSC 433 EXAM 3 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTION.
a "dry tap" bone marrow aspiration may be seen with what chronic myeloid proliferative disease?
A: essential thrombocythemia
B: polycythemia vera
C: primary myelofibrosis
D: Chronic myeloid leukemia - (ANSWER)Primary myelofibrosis
what clinical feature is more often associated with essential thrombocythemia than with the other
chronic myeloproliferative disorders?
A: bleeding and thrombosis
B: infections
C: splenomegaly
D: fatigue - (ANSWER)bleeding and thromboses
what is the most common chromosomal abnormality in polycythemia vera (PV)?
A: BCR-ABL
B: PML-RARA
C: TET-2
D: JAK2V617F - (ANSWER)JAK2V617F
which of the following is an expected finding in polycythemia vera?
A: normal white cell count
B: anemia
C: increased RBC mass
D: low leukocyte alkaline phosphatase - (ANSWER)increased RBC mass
, MMSC 433 EXAM 3 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTION.
a patient has a normal white cell count, a moderately high platelet count, and mild anemia. The
differential shows immature granulocytes, nucleated red cells, and teardrop-shaped red cells. Which of
the following is most likely?
A: chronic myelogenous leukoemia
B: primary myelofibrosis
C: polycythemia vera
D: essential thrombocythemia - (ANSWER)primary myelofibrosis
a patient has a platelet count of 1200*10⁹/L. Many platelets are giant and have abnormal shapes. A mild
anemia is present. The bone marrow has increased megakaryocytes in clusters; iron stores are present.
Which of the following is most likely?
A: chronic myelogenous leukemia
B: polycythemia vera
C: thrombosis secondary to blood loss
D: essential thrombocythemia - (ANSWER)essential thrombocythemia
which one of the following chromosome abnormalities is associated with CML?
A: t(8;14)
B: trisomy 18
C: t(15;17)
D: t(9;22) - (ANSWER)t(9;22)
all of the following are minor criteria for overt PMF, except:
A: WBC count < 10*10⁹/L
a "dry tap" bone marrow aspiration may be seen with what chronic myeloid proliferative disease?
A: essential thrombocythemia
B: polycythemia vera
C: primary myelofibrosis
D: Chronic myeloid leukemia - (ANSWER)Primary myelofibrosis
what clinical feature is more often associated with essential thrombocythemia than with the other
chronic myeloproliferative disorders?
A: bleeding and thrombosis
B: infections
C: splenomegaly
D: fatigue - (ANSWER)bleeding and thromboses
what is the most common chromosomal abnormality in polycythemia vera (PV)?
A: BCR-ABL
B: PML-RARA
C: TET-2
D: JAK2V617F - (ANSWER)JAK2V617F
which of the following is an expected finding in polycythemia vera?
A: normal white cell count
B: anemia
C: increased RBC mass
D: low leukocyte alkaline phosphatase - (ANSWER)increased RBC mass
, MMSC 433 EXAM 3 QUESTIONS AND ANSWERS WITH COMPLETE SOLUTION.
a patient has a normal white cell count, a moderately high platelet count, and mild anemia. The
differential shows immature granulocytes, nucleated red cells, and teardrop-shaped red cells. Which of
the following is most likely?
A: chronic myelogenous leukoemia
B: primary myelofibrosis
C: polycythemia vera
D: essential thrombocythemia - (ANSWER)primary myelofibrosis
a patient has a platelet count of 1200*10⁹/L. Many platelets are giant and have abnormal shapes. A mild
anemia is present. The bone marrow has increased megakaryocytes in clusters; iron stores are present.
Which of the following is most likely?
A: chronic myelogenous leukemia
B: polycythemia vera
C: thrombosis secondary to blood loss
D: essential thrombocythemia - (ANSWER)essential thrombocythemia
which one of the following chromosome abnormalities is associated with CML?
A: t(8;14)
B: trisomy 18
C: t(15;17)
D: t(9;22) - (ANSWER)t(9;22)
all of the following are minor criteria for overt PMF, except:
A: WBC count < 10*10⁹/L
