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USMLE Step 1 Rapid Review 2026 |
Medical School Exam Prep | Verified
Questions & Answers | Student-Approved
Real Exam Resource
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF
without JVD) -- Verified--Solution----Budd-Chiari syndrome
Achilles tendon xanthoma -- Verified--Solution----Familial
hypercholesterolemia
Adrenal hemorrhage, hypotension, DIC -- Verified--Solution----
Waterhouse-Friderichsen syndrome (meningococcemia)
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints -
- Verified--Solution----Marfan's (fibrillin defect)
Athlete with polycythemia -- Verified--Solution----Erythropoietin
injection
Back pain, fever, night sweats, weight loss -- Verified--Solution----Pott's
(TB to the vertebrae)
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Bilateral hilar adenopathy, uveitis -- Verified--Solution----Sarcoid
Blue sclera -- Verified--Solution----Osteogenesis imperfecta
Bluish line on gingiva -- Verified--Solution----Burton's line - lead
poisoning
Bone pain, bone enlargement, arthritis, (also increased hat size, fracture,
increased alk phos) -- Verified--Solution----Paget's
Bounding pulses, diastolic hear murmur, head bobbing -- Verified--
Solution----Aortic regurg
Café-au-lait spots, Lisch nodules -- Verified--Solution----NF (1 = optic
glimoas and pheo, 2 = acoustic Schwannomas)
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty --
Verified--Solution----McCune-Albright syndome (G protein problem)
Calf pseudohypertrophy -- Verified--Solution----Duchenne's muscular
dystrophy
Cherry-red spot on macula -- Verified--Solution----Tay-Sachs,
Niemann-Pick, central retinal artery occlusion
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Chest pain, pericardial effusion/friction rub, persistent fever following
MI -- Verified--Solution----Dressler's (autoimmune post-MI)
Child uses arms to stand up from squat -- Verified--Solution----Gower's
sign (Duchenne's)
Child with fever develops red rash on face that spreads to body --
Verified--Solution----Slapped cheek - B19
Chorea, dementia, caudate degeneration -- Verified--Solution----
Huntington's
Chronic exercise intolerance with myalgia, fatigue, painful cramps --
Verified--Solution----McArdle's (muscle phosphorylase deficiency)
Cold intolerance -- Verified--Solution----Hypothyroidism
Conjugate lateral gaze palsy, horizontal diplopia -- Verified--Solution---
-Internuclear ophthalmoplegia (MS or stroke)
Continuous machinery heart murmur -- Verified--Solution----PDA
Cutaneous/dermal edema due to CT expansion -- Verified--Solution----
Myxedema
USMLE Step 1 Rapid Review 2026 |
Medical School Exam Prep | Verified
Questions & Answers | Student-Approved
Real Exam Resource
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF
without JVD) -- Verified--Solution----Budd-Chiari syndrome
Achilles tendon xanthoma -- Verified--Solution----Familial
hypercholesterolemia
Adrenal hemorrhage, hypotension, DIC -- Verified--Solution----
Waterhouse-Friderichsen syndrome (meningococcemia)
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints -
- Verified--Solution----Marfan's (fibrillin defect)
Athlete with polycythemia -- Verified--Solution----Erythropoietin
injection
Back pain, fever, night sweats, weight loss -- Verified--Solution----Pott's
(TB to the vertebrae)
,2 | Page
Bilateral hilar adenopathy, uveitis -- Verified--Solution----Sarcoid
Blue sclera -- Verified--Solution----Osteogenesis imperfecta
Bluish line on gingiva -- Verified--Solution----Burton's line - lead
poisoning
Bone pain, bone enlargement, arthritis, (also increased hat size, fracture,
increased alk phos) -- Verified--Solution----Paget's
Bounding pulses, diastolic hear murmur, head bobbing -- Verified--
Solution----Aortic regurg
Café-au-lait spots, Lisch nodules -- Verified--Solution----NF (1 = optic
glimoas and pheo, 2 = acoustic Schwannomas)
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty --
Verified--Solution----McCune-Albright syndome (G protein problem)
Calf pseudohypertrophy -- Verified--Solution----Duchenne's muscular
dystrophy
Cherry-red spot on macula -- Verified--Solution----Tay-Sachs,
Niemann-Pick, central retinal artery occlusion
, 3 | Page
Chest pain, pericardial effusion/friction rub, persistent fever following
MI -- Verified--Solution----Dressler's (autoimmune post-MI)
Child uses arms to stand up from squat -- Verified--Solution----Gower's
sign (Duchenne's)
Child with fever develops red rash on face that spreads to body --
Verified--Solution----Slapped cheek - B19
Chorea, dementia, caudate degeneration -- Verified--Solution----
Huntington's
Chronic exercise intolerance with myalgia, fatigue, painful cramps --
Verified--Solution----McArdle's (muscle phosphorylase deficiency)
Cold intolerance -- Verified--Solution----Hypothyroidism
Conjugate lateral gaze palsy, horizontal diplopia -- Verified--Solution---
-Internuclear ophthalmoplegia (MS or stroke)
Continuous machinery heart murmur -- Verified--Solution----PDA
Cutaneous/dermal edema due to CT expansion -- Verified--Solution----
Myxedema
