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Intro Medical-Surgical Nursing by Timby & Smith: Ch 50 Caring for Clients with Disorders of the Endocrine System Parathyroid, and Adrenal Gland Dysfunction Including Hyper- and Hyposecretory States, Autoimmune Thyroid Diseases (Graves’ and Hashimoto’s), M

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Intro Medical-Surgical Nursing by Timby & Smith: Ch 50 Caring for Clients with Disorders of the Endocrine System Parathyroid, and Adrenal Gland Dysfunction Including Hyper- and Hyposecretory States, Autoimmune Thyroid Diseases (Graves’ and Hashimoto’s), Metabolic and Electrolyte Imbalances, Hormonal Crisis Syndromes (Thyrotoxic Crisis, Addisonian Crisis, SIADH), Tumors and Hyperplasia, Surgical Interventions (Adrenalectomy, Thyroidectomy, Hypophysectomy), and Multisystem Clinical Manifestations Across Cardiovascular, Neurologic, Metabolic, and Reproductive Systems Exam Questions Veerified and Provided with Complete A+ Graded Answers Latest Updated 2026 acromegaly condition in which growth hormone is over secreted after the epiphyses of the long bones have sealed addisonian crisis life-threatening endocrine emergency when corticosteroid therapy is abruptly discontinued adrenalectomy surgical removal of the adrenal gland(s), usually to remove a cancerous tumor adrenal insufficiency decreased adrenal cortical function carpopedal spasm involuntary contraction of hand muscles cushingoid syndrome physical changes that accompany excess endogenous production of steroid hormones or long-term corticosteroid therapy Cushing's syndrome endocrine disorder that results from excessive secretion of hormones by the adrenal cortex diabetes insipidus endocrine disorder that develops when antidiuretic hormone from the posterior pituitary gland is insufficient goiter enlarged thyroid gland hyperaldosteronism excessive secretion of aldosterone leading to extreme electrolyte imbalances hyperparathyroidism disorder of the parathyroid gland that affects calcium and phosphorus levels Hyperplasia increase in the number of cells hyperthyroidism disorder associated with hypersecretion of thyroid hormones in which metabolic rate increases hypoparathyroidism deficiency of parathormone that results in hypocalcemia hypophysectomy surgical removal of the pituitary gland hypothyroidism disorder that occurs when the thyroid gland fails to secrete adequate thyroid hormones myxedema hypothyroidism in an adult pheochromocytoma tumor of the adrenal medulla that causes hyperfunction Simmonds' disease rare endocrine disorder caused by destruction of the pituitary gland Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH) phenomenon that alters fluid and electrolyte balance due to excessive release of ADH tetany group of signs and symptoms associated with hypocalciemia thyroidectomy removal of part or all of the thyroid gland thyroiditis inflammation of the thyroid gland thyrotoxic crisis abrupt and life-threatening form of hyperthyroidism, thought to be triggered by extreme stress, infection, diabetic ketoacidosis, trauma, toxemia of pregnancy, or manipulation of a hyperactive thyroid gland during surgery or physical examination hypertrophy

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Intro Medical-Surgical Nursing by Timby & Smith:
Ch 49 Introduction to the Endocrine System
Anatomy and Hormonal Regulation Examination:
Hypothalamic–Pituitary Axis Control Mechanisms,
Anterior and Posterior Pituitary Hormones (TSH,
ACTH, GH, LH, FSH, Prolactin, ADH, Oxytocin),
Adrenal Cortex and Medulla Secretions
(Glucocorticoids, Mineralocorticoids,
Gonadocorticoids, Epinephrine, Norepinephrine),
Thyroid and Parathyroid Hormone Physiology (T3,
T4, Calcitonin, PTH), Pancreatic Islet Hormones
(Insulin, Glucagon, Somatostatin), Gonadal
Steroidogenesis (Estrogen, Progesterone,
Testosterone), Feedback Loops, Neurohormonal
Regulation, and Integrated Metabolic,
Reproductive, and Stress Response Functions Exam
Questions Verified and Provided with Complete A+
Graded Rationales Latest Updated 2026


adenohypophysis

anterior lobe of the pituitary gland

adrenal cortex

outer portion of the adrenal gland; manufactures and secretes glusosorticoids,
mineralocorticoids, and small amounts of sex hormones

adrenal glands

glands located above the kidneys; the outer portion is the cortex, and the inner portion is the
medulla

adrenal medulla

, inner portion of the adrenal glnads; secrets epinephrine and norepiniphrine, two hormones
released in response to stress of threat to life

Adrenocorticotropic hormone (ACTH)

substance secreted by the pituitary that stimulates the adrenal glands to secrete corticosteroid
hormones

Corticosteroids

collective term for the glucocorticoids, mineralocorticoids, and small amounts of sex hormones
manufactured and secreted by the adrenal cortex

Corticotropin-releasing hormone (CRH)

causes the anterior pituitary gland to secrete adrenocorticotropic hormone (ACTH)

estrogen

hormone produced by the ovaries

feedback loop

mechanism that turns hormone production off and on; negative feedback stimulates a releasing
gland in response to a decrease inlevels while positive feedback keeps concentrations of
hormones within a stable range

Follicle-stimulating hormone (FSH)

a hormone that stimulates the development of ovum in the ovaries and the sperm in the testes

glucagon

hormone that increases blood sugar levels by stimulating the breakdown of glycogen into
glucose in the liver

glycogenolysis

process in which glycogen is broken down into glucose in the liver

Gonadotropin-releasing hormone (GnRH)

triggers sexual development at the onset of puberty and contines to cause the anterior pityitary
gland to secrete lutenizing hormone and follicle-stimulating hormone

hormones

chemicals secreted by the endocrine glands that accelerate or slow physiologic processes

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