COMSAE Phase2 Form C114 Practice
Exam Questions And Correct Answers
(Verified Answers) Plus Rationales
2026|2027 Q&A | Instant Download Pdf
1. A 24-year-old woman presents with fever, dysuria, and flank pain.
Urinalysis shows WBC casts.
A. Cystitis
B. Glomerulonephritis
C. Pyelonephritis
D. Nephrolithiasis
E. Interstitial cystitis
Rationale: White blood cell casts plus flank pain indicate renal parenchymal
infection, consistent with pyelonephritis.
2. A 67-year-old man with COPD develops acute confusion after receiving
high-flow oxygen. ABG shows pH 7.28, PaCO₂ 65 mmHg.
A. Metabolic acidosis
B. Metabolic alkalosis
,C. Respiratory acidosis
D. Respiratory alkalosis
E. Mixed acidosis
Rationale: COPD with elevated CO₂ and low pH indicates respiratory acidosis
due to hypoventilation.
3. A 32-year-old woman presents with palpitations, weight loss, and heat
intolerance. Exam shows diffuse goiter and pretibial myxedema.
A. Toxic multinodular goiter
B. Thyroiditis
C. Graves disease
D. Subacute thyroiditis
E. Thyroid carcinoma
Rationale: TSI-mediated hyperthyroidism causes diffuse goiter and
dermopathy characteristic of Graves.
4. A 5-year-old child has a sandpaper rash after pharyngitis.
A. Measles
B. Rubella
C. Scarlet fever
D. Kawasaki disease
E. Fifth disease
Rationale: Group A Streptococcus infection with strawberry tongue and fine
rash indicates scarlet fever.
,5. A 58-year-old smoker has hematuria and flank mass on exam.
A. Bladder cancer
B. Renal stone
C. Renal cell carcinoma
D. Pyelonephritis
E. Polycystic kidney disease
Rationale: Classic triad of hematuria, flank pain, and mass suggests renal
cell carcinoma.
6. A 26-year-old woman has malar rash, joint pain, and photosensitivity.
ANA and anti-dsDNA positive.
A. Rheumatoid arthritis
B. Dermatomyositis
C. Systemic lupus erythematosus
D. Sjögren syndrome
E. Scleroderma
Rationale: Anti-dsDNA is specific for lupus; malar rash and arthritis confirm
diagnosis.
7. A 45-year-old man presents with hematemesis after several episodes of
vomiting.
A. Peptic ulcer disease
B. Esophageal varices
C. Mallory-Weiss tear
D. Boerhaave syndrome
, E. Gastritis
Rationale: Mucosal laceration at gastroesophageal junction after retching
indicates Mallory-Weiss tear.
8. A 19-year-old college student develops a petechial rash and meningitis.
A. Streptococcus pneumoniae
B. Neisseria meningitidis
C. Listeria monocytogenes
D. E. coli
E. HSV
Rationale: Meningococcal infection common in young adults, causing
petechial rash and meningitis.
9. A 64-year-old man with prostate cancer develops back pain and
hyperreflexia.
A. Cauda equina syndrome
B. Disk herniation
C. Spinal cord compression
D. Sciatica
E. Ankylosing spondylitis
Rationale: Metastasis to spine compresses cord causing upper motor neuron
signs.
10. A newborn has continuous machinery-like murmur.
A. Atrial septal defect
B. Ventricular septal defect
Exam Questions And Correct Answers
(Verified Answers) Plus Rationales
2026|2027 Q&A | Instant Download Pdf
1. A 24-year-old woman presents with fever, dysuria, and flank pain.
Urinalysis shows WBC casts.
A. Cystitis
B. Glomerulonephritis
C. Pyelonephritis
D. Nephrolithiasis
E. Interstitial cystitis
Rationale: White blood cell casts plus flank pain indicate renal parenchymal
infection, consistent with pyelonephritis.
2. A 67-year-old man with COPD develops acute confusion after receiving
high-flow oxygen. ABG shows pH 7.28, PaCO₂ 65 mmHg.
A. Metabolic acidosis
B. Metabolic alkalosis
,C. Respiratory acidosis
D. Respiratory alkalosis
E. Mixed acidosis
Rationale: COPD with elevated CO₂ and low pH indicates respiratory acidosis
due to hypoventilation.
3. A 32-year-old woman presents with palpitations, weight loss, and heat
intolerance. Exam shows diffuse goiter and pretibial myxedema.
A. Toxic multinodular goiter
B. Thyroiditis
C. Graves disease
D. Subacute thyroiditis
E. Thyroid carcinoma
Rationale: TSI-mediated hyperthyroidism causes diffuse goiter and
dermopathy characteristic of Graves.
4. A 5-year-old child has a sandpaper rash after pharyngitis.
A. Measles
B. Rubella
C. Scarlet fever
D. Kawasaki disease
E. Fifth disease
Rationale: Group A Streptococcus infection with strawberry tongue and fine
rash indicates scarlet fever.
,5. A 58-year-old smoker has hematuria and flank mass on exam.
A. Bladder cancer
B. Renal stone
C. Renal cell carcinoma
D. Pyelonephritis
E. Polycystic kidney disease
Rationale: Classic triad of hematuria, flank pain, and mass suggests renal
cell carcinoma.
6. A 26-year-old woman has malar rash, joint pain, and photosensitivity.
ANA and anti-dsDNA positive.
A. Rheumatoid arthritis
B. Dermatomyositis
C. Systemic lupus erythematosus
D. Sjögren syndrome
E. Scleroderma
Rationale: Anti-dsDNA is specific for lupus; malar rash and arthritis confirm
diagnosis.
7. A 45-year-old man presents with hematemesis after several episodes of
vomiting.
A. Peptic ulcer disease
B. Esophageal varices
C. Mallory-Weiss tear
D. Boerhaave syndrome
, E. Gastritis
Rationale: Mucosal laceration at gastroesophageal junction after retching
indicates Mallory-Weiss tear.
8. A 19-year-old college student develops a petechial rash and meningitis.
A. Streptococcus pneumoniae
B. Neisseria meningitidis
C. Listeria monocytogenes
D. E. coli
E. HSV
Rationale: Meningococcal infection common in young adults, causing
petechial rash and meningitis.
9. A 64-year-old man with prostate cancer develops back pain and
hyperreflexia.
A. Cauda equina syndrome
B. Disk herniation
C. Spinal cord compression
D. Sciatica
E. Ankylosing spondylitis
Rationale: Metastasis to spine compresses cord causing upper motor neuron
signs.
10. A newborn has continuous machinery-like murmur.
A. Atrial septal defect
B. Ventricular septal defect
