Management Questions and Answers
2026
principlesBforBpracticeB-
BAnswer•BTheBskinBisBtheBlargestBexternalBorgan.BItBhasBtwoBlayers:BtheBepidermisBandBtheB
dermisB(Fig.B39.1).BTheBepidermisBhasBfiveBlayers.
•BStratumBcorneum,BtheBoutermostBlayer,BconsistsBofBflattenedBdeadBkeratinizedBcells.BStratu
mBcorneumBpreventsBdehydrationBofBunderlyingBcellsBandBisBaBphysicalBbarrierBtoBtheBentryB
ofBcertainBchemicals.BThisBlayerBisBlikeBtheBshinglesBonBaBroofBthatBprovidesBprotectionBfrom
BoutsideBelements.
•BTheBnextBlayersBofBtheBepidermisBareBtheBstratumBlucidum,BstratumBgranulosum,BandBstrat
umBspinosum.
•BStratumBgerminativum,BtheBinnermostBlayer,BisBsometimesBcalledBtheBbasalBlayer.BImportant
BfeaturesBofBtheBstratumBgerminativumBareBtheBepidermalBprotrusions,BorB"peaksBandBvalleys
"BthatBpointBdownwardBintoBtheBdermis.BTheseBprovideBresiliencyBandBintegrityBtoBtheBskinB
structure.BMelanocytes,BtheBcellsBthatBgiveBtheBskinBitsBcolor,BareBalsoBinBthisBlayer.
•BTheBareaBthatBseparatesBtheBepidermisBfromBtheBdermisBisBcalledBtheBdermoepidermalBjun
ctionBorBtheBbasementBmembraneBzone.
•BBeneathBtheBepidermisBisBtheBdermis.BCollagenB(aBtoughBfibrousBproteinBlayer),BbloodBvess
els,BandBnervesBcomposeBtheBdermalBlayer.BCollagenBcomposesBaboutB70%BofBtheBdermisBan
dBisBextremelyBimportantBinBwoundBhealing.BTheBdermisBrestoresBtheBphysicalBpropertiesBofB
theBskinBandBitsBstructuralBintegrity.BRestorationBofBbothBtheBepidermalBandBdermalBlayersBis
BnecessaryBtoBpromoteBhealing.BRiskBforBlocalBorBsystemicBinfection,BimpairedBcirculation,Ban
dBbreakdownBofBtissueBdirectlyBimpairsBtheBwound-
healingBabilityBofBtheBskinBlayersB(DoughtyBandBSparks-Defriese,B2016).
•BWoundsBshouldBbeBassessedBonBaBscheduledBbasisBtoBdetermineBifBtheBwoundBisBmovingB
towardBhealing.BIfBtheBassessmentBrevealsBthatBtheBwoundBisBnotBprogressingBasBexpected,Bt
heBplanBofBcareBcanBbeBchangedBtoBfacilitateBwoundBhealingB(seeBProceduralBGuidelineB39
Black/brownBwounds/escharB-BAnswer-BlackBorBbrownBtissueBisBeschar,BwhichBrepresentsBfull-
thicknessBtissueBdestruction.BBlackBisBusedBtoBdescribeBnecroticBtissueBorBdesiccatedBtissueBs
uchBasBtendon.BItBisBalsoBrelatedBtoBgangrenousBlesionsBsecondaryBtoBperipheralBvascularBdis
ease.
-
IfBtheBgoalBforBaBwoundBcoveredBwithBescharBisBdebridement,BsharpBdebridementBisBusedBt
oBquicklyBremoveBtheBtissue,BchemicalBdebridementBisBusedBtoBsoftenBtheBtissueBforBremoval
,BorBaBmoistBdressingBisBalsoBconsideredBtoBloosenBtheBtissue.BTheBmethodBofBdebridementB
dependsBonBtheBoverallBgoalBforBtheBpatient.
, YellowBwounds/sloughB-BAnswer-
YellowBtissueBrepresentsBnonviableBtissueBandBinBsomeBcasesBtheBpresenceBofBanBinfection.B
SloughBtissueBcanBbeByellow;BcreamBcolored;BorBgrayBslough,BwhichBisBusuallyBaccompaniedB
byBpurulentBdrainage.
-ForBpatientsBwithBaBlowBinfectionBrisk,BtheBuseBofBmoisture-
retentiveBdressingsBenhancesBdebridementBofBtheByellow/sloughBtissue.BMoisture-
retentiveBdressingsBmayBincludeBmoistBdressings,Bhydrocolloids,Bhydrogels,BorBalginates.BIfBthe
BwoundBisBinfected,BtopicalBantimicrobialsBareBused.
RedBwounds/granulationB-BAnswer-
RedBtissueBrepresentsBtheBpresenceBofBgranulationBtissue.BTheBredBcolorBisBtheBresultBofBan
BincreasingBamountBofBnewBbloodBvesselsBinBtheBwoundBandBisBconsideredBhealthy.
-
TheBgoalBinBmanagementBofBaBredBgranulatedBwoundBisBtoBselectBaBdressingBthatBmaintains
BaBcleanBandBmoistBwoundBenvironmentBandBminimizesBdamageBtoBhealingBtissue.
FactorsBthatBInfluenceBWoundBHealingB-
BAnswer•BHypovolemia,Bhypotension,Bvasoconstriction,Bedema,BandBhypoxiaBnegativelyBaffectB
woundBhealingBbecauseBadequateBperfusionBandBoxygenationBareBnecessaryBforBnewBvesselBd
evelopment,BcollagenBsynthesis,BandBdevelopmentBofBtensileBstrength.
•BAnBadequateBnutritionalBstatusBisBcriticalBforBcollagenBsynthesis,BtensileBstrength,BandBimm
uneBfunction.
•BWoundBinfectionBprolongsBtheBinflammatoryBresponse,BandBtheBmicroorganismsBuseBnutrien
tsBandBoxygenBneededBforBwoundBrepair.
•BABpatientBwithBdiabetesBmellitusBmayBhaveBimpairedBwoundBhealingBbecauseBofBabnormal
BandBprolongedBinflammation,BreducedBcollagenBsynthesis,BandBimpairedBepithelialBmigration.
BHyperglycemiaBisBassociatedBwithBcompromisedBneutrophilBfunctionBandBimpairedBmigration.
•BCorticosteroidBtherapyBorBtheBuseBofBotherBimmunosuppressiveBagentsBsuchBasBchemother
apyBincreasesBtheBpatient'sBsusceptibilityBtoBinfection.
•BAdvancedBageBcanBcontributeBtoBaBdiminishedBproliferationBofBcellsBcriticalBtoBrepair.
PerformingBaBWoundBAssessmentB-BAnswer-
WoundBassessmentBprovidesBtheBbaselineBforBplanningBandBevaluatingBtheBwoundBcareBplan.
BNormalBwoundBhealingBoccursBinBanBorganizedBfashion,BandBevaluatingBtheBwoundBstatusBp
rovidesBanBongoingBassessmentBofBwoundBhealingBandBhelpsBtoBdetermineBwoundBtreatment
s.BTheBfrequencyBofBwoundBassessmentBdependsBonBtheBpatient'sBoverallBcondition,BpolicyBo
fBtheBhealthBcareBsetting,BtypeBofBdressingsBused,BandBoverallBpatientBgoalsB(Nix,B2016).BAcu
teBcareBsettingsBgenerallyBrequireBwoundBassessmentBdailyBorBwithBeachBdressingBchange.BLo
ng-
termBcareBfacilitiesBmayBrequireBanBinitialBadmissionBwoundBassessmentBandBweeklyBassessm
entBforBchronicBwounds.BCheckBagencyBpolicyBforBfrequencyBofBwoundBassessmentBandBspeci