ABIM CERTIFICATION 2026 FULL STUDY
PACK WITH VERIFIED Q&A SOLUTIONS
◉What condition is often associated with antibodies positive to
glutamic acid decarboxylase? Answer: Type 1 Diabetes Mellitus
◉What is the main pulmonary function test that helps differentiate
obstructive from restrictive lung disease? Answer: Total lung
capacity (TLC)
◉What would you expect pleural effusion glucose level to be in
individuals with rheumatoid arthritis? Answer: Less than 30 mg/dl
◉How do residual lung volumes and DLCO change with kyphosis
compared to normal lungs? Answer: DLCO remains normal while
residual lung volumes are increased compared to normal
◉With allergic bronchopulmonary aspergillosis (ABPA), what two
labs will be increased? Answer: IgE and peripheral eosinophils
greater than 10 percent
◉What is the most common presenting symptom of an individual
with acute altitude sickness? Answer: Headaches
,◉What is the treatment of M3 form of AML? Answer: All-Trans
Retinoic Acid (ATRA)
◉Which organism can be associated with Burkitt's Lymphoma and
nasopharyngeal carcinoma? Answer: Epstein-Barr Virus (EBV)
◉Which myeloproliferative disorder is associated with BCR-ABL or t
(9,22) translocation? Answer: Chronic Myelogenous Leukemia
(CML)
◉Breast cancer along with sarcomas, leukemia, lymphoma, brain
tumors and adrenal cancer defines which syndrome? Answer: Li-
Fraumeni Syndrome
◉Trastuzumab is used for what positive marker in patients with
breast cancer? Answer: HER2/neu positive
◉Which form of lung cancer is most often associated with ectopic
production of parathyroid hormone-related peptide (PTHrp)?
Answer: Squamous cell carcinoma of the lung
◉What are the CD markers for a Reed Sternberg cell in Hodgkin's
lymphoma? Answer: CD15 and CD30
,◉Which marker is often associated with pancreatic cancer? Answer:
CA 19-9
◉Which marker is often associated with ovarian cancer? Answer: CA
125
◉What is the most important prognostic factor in a patient with
breast cancer? Answer: Lymph node positivity
◉What is the most common electrolyte abnormality associated with
tamoxifen use? Answer: Hypercalcemia
◉Post renal transplant lymphoma is most often associated with
which organism? Answer: Epstein Barr Virus (EBV)
◉What is the most common subytpe of thyroid cancer? Answer:
Papillary thyroid cancer (papillary carcinoma)
◉Sweet's Syndrome can be associated with what type of
malignancy? Answer: Acute myelogenous leukemia
◉Which type of lung cancer can give a paraneoplastic syndrome of
gynecomastia? Answer: Large cell carcinoma
, ◉What group of testicular cancer is not sensitive to radiation
therapy? Answer: Non-seminomas (eg. teratoma, embryonal
carcinoma, choriocarcinoma, yolk sac tumor)
◉Which type of cancer is least likely to metastasize to the brain and
usually produces blastic bone lesions? Answer: Prostate cancer
◉Which type of beta blockers are okay to give to patients with
hypertension and asthma? Answer: Cardioselective beta blockers
(metoprolol, atenolol, bisoprolol, nebivolol)
◉Which two murmurs will decrease in intensity with squatting,
sitting or leg raising? Answer: Hypertrophic obstructive
cardiomyopathy and Mitral valve prolapse
◉Which congestive heart failure medication is used for symptomatic
relief but does not decrease mortality? Answer: Furosemide (Lasix)
◉What cardiac condition has a loud holosystolic murmur w/
palpable thrill along left sternal border over 3rd or 4th intercostal
space? Answer: Ventricular septal defect (VSD)
◉What is the leading cause of sudden cardiac death in young
athletes? Answer: Hypertrophic cardiomyopathy
PACK WITH VERIFIED Q&A SOLUTIONS
◉What condition is often associated with antibodies positive to
glutamic acid decarboxylase? Answer: Type 1 Diabetes Mellitus
◉What is the main pulmonary function test that helps differentiate
obstructive from restrictive lung disease? Answer: Total lung
capacity (TLC)
◉What would you expect pleural effusion glucose level to be in
individuals with rheumatoid arthritis? Answer: Less than 30 mg/dl
◉How do residual lung volumes and DLCO change with kyphosis
compared to normal lungs? Answer: DLCO remains normal while
residual lung volumes are increased compared to normal
◉With allergic bronchopulmonary aspergillosis (ABPA), what two
labs will be increased? Answer: IgE and peripheral eosinophils
greater than 10 percent
◉What is the most common presenting symptom of an individual
with acute altitude sickness? Answer: Headaches
,◉What is the treatment of M3 form of AML? Answer: All-Trans
Retinoic Acid (ATRA)
◉Which organism can be associated with Burkitt's Lymphoma and
nasopharyngeal carcinoma? Answer: Epstein-Barr Virus (EBV)
◉Which myeloproliferative disorder is associated with BCR-ABL or t
(9,22) translocation? Answer: Chronic Myelogenous Leukemia
(CML)
◉Breast cancer along with sarcomas, leukemia, lymphoma, brain
tumors and adrenal cancer defines which syndrome? Answer: Li-
Fraumeni Syndrome
◉Trastuzumab is used for what positive marker in patients with
breast cancer? Answer: HER2/neu positive
◉Which form of lung cancer is most often associated with ectopic
production of parathyroid hormone-related peptide (PTHrp)?
Answer: Squamous cell carcinoma of the lung
◉What are the CD markers for a Reed Sternberg cell in Hodgkin's
lymphoma? Answer: CD15 and CD30
,◉Which marker is often associated with pancreatic cancer? Answer:
CA 19-9
◉Which marker is often associated with ovarian cancer? Answer: CA
125
◉What is the most important prognostic factor in a patient with
breast cancer? Answer: Lymph node positivity
◉What is the most common electrolyte abnormality associated with
tamoxifen use? Answer: Hypercalcemia
◉Post renal transplant lymphoma is most often associated with
which organism? Answer: Epstein Barr Virus (EBV)
◉What is the most common subytpe of thyroid cancer? Answer:
Papillary thyroid cancer (papillary carcinoma)
◉Sweet's Syndrome can be associated with what type of
malignancy? Answer: Acute myelogenous leukemia
◉Which type of lung cancer can give a paraneoplastic syndrome of
gynecomastia? Answer: Large cell carcinoma
, ◉What group of testicular cancer is not sensitive to radiation
therapy? Answer: Non-seminomas (eg. teratoma, embryonal
carcinoma, choriocarcinoma, yolk sac tumor)
◉Which type of cancer is least likely to metastasize to the brain and
usually produces blastic bone lesions? Answer: Prostate cancer
◉Which type of beta blockers are okay to give to patients with
hypertension and asthma? Answer: Cardioselective beta blockers
(metoprolol, atenolol, bisoprolol, nebivolol)
◉Which two murmurs will decrease in intensity with squatting,
sitting or leg raising? Answer: Hypertrophic obstructive
cardiomyopathy and Mitral valve prolapse
◉Which congestive heart failure medication is used for symptomatic
relief but does not decrease mortality? Answer: Furosemide (Lasix)
◉What cardiac condition has a loud holosystolic murmur w/
palpable thrill along left sternal border over 3rd or 4th intercostal
space? Answer: Ventricular septal defect (VSD)
◉What is the leading cause of sudden cardiac death in young
athletes? Answer: Hypertrophic cardiomyopathy
