UWORLD/RXPREP: Immunizations/Travelers 2026 || A+
Verified.
Herd immunity correct answers The resistance of a group to an attack by a disease to which a
large proportion of the members of the group are immune
What are the 3 main vaccine resources? correct answers - FDA
- Advisory Committee on Immunization Practices (ACIP): issues *recommendations* for
vaccine administration
- CDC: approves ACIP recommendations (MMWR, usually updated weekly and "The Pink
Book")
What is a reliable vaccine information for *patients*? correct answers The Vaccine Information
Statement (VIS)
Must be given before vaccine administration to patient
Do vaccines cause autism? correct answers No, there is absolutely no evidence that the two are
related, and the most popular study that claimed to have discovered a link was discovered to be
fraudulent (about Thmerosal)
Active immunity correct answers A form of acquired immunity in which the body produces its
own antibodies against disease-causing antigens.
Usually permanent and may be acquired from:
- Surviving infection
- Vaccination
Passive immunity correct answers Immunity conferred by transferring antibodies from an
individual who is immune to a pathogen to another individual
____________________ use the *killed version* of a virus or bacteria that causes the disease
correct answers Inactivated vaccines
What is a limitation of inactivated vaccines? correct answers Immunity isn't as strong; therefore,
booster may be required for ongoing immunity
Types of inactivated vaccines correct answers - Polysaccharide *(do not produce a good immune
response in children less than 2 yrs)*, ex. Pneumovax 23
- Conjugate (polysaccharide from bacteria binds to carrier proteins), increases immune response
in infants, ex. Prevnar 13, Hib, and Meningococcal
- Recombinant (gene segment insertion), ex. Gardasil, Influenza, Flubok Quadrivalent
___________________ are most similar to the actual disease and provide a strong, long-lasting
immune response correct answers Live attenuated (weaker) vaccines
, Made from viruses or bacteria; must replicate to work, produce strong immune response
What is a C/I in a *live vaccine*? correct answers Patients who are *immunocompromised and
pregnant*; circulating antibodies can interfere with vaccine replication
Live vaccine acronym correct answers *COZY IV RM*
C = Cholera
O = Oral Typhoid
Z = Zoster (Zostavax) - no longer available
Y = Yellow Fever
I = Intranasal Influenza
V = Varicella
R = Rotavirus
M = MMR
Vaccines can be given _________________________ correct answers simultaneously
Note: lives can also be separated 4 weeks apart
Live vaccines and antibody correct answers
Live vaccines and TB skin test (TST) correct answers Live vaccines can cause a false negative
TST result. There are *3 options* to reduces this risk (see p. 311)
Where are vaccine AEs reported? correct answers VAERS!
Annual influenza vaccine is for all special groups greater than or equal to what age? correct
answers 6 months!
VACCINATIONS FOR SPECIFIC POPS: PREGGERS correct answers - Influenza, inactivated
(during any trimester)
- Tdap x with *each pregnancy* (weeks 27-36 optimally), make sure those in close contact with
baby get the vaccine
VACCINATIONS FOR SPECIFIC POPS: ASPLENIA correct answers - Hib
- Pneumo vaccines (Prevnar 13 and Pneumovax 23)
- Meningococcal
VACCINATIONS FOR SPECIFIC POPS: IMMUNODEFICIENCY correct answers - Pneumo
vaccines (Prevnar 13 and Pneumovax 23)
If have HIV:
- Meningococcal conjugate
Verified.
Herd immunity correct answers The resistance of a group to an attack by a disease to which a
large proportion of the members of the group are immune
What are the 3 main vaccine resources? correct answers - FDA
- Advisory Committee on Immunization Practices (ACIP): issues *recommendations* for
vaccine administration
- CDC: approves ACIP recommendations (MMWR, usually updated weekly and "The Pink
Book")
What is a reliable vaccine information for *patients*? correct answers The Vaccine Information
Statement (VIS)
Must be given before vaccine administration to patient
Do vaccines cause autism? correct answers No, there is absolutely no evidence that the two are
related, and the most popular study that claimed to have discovered a link was discovered to be
fraudulent (about Thmerosal)
Active immunity correct answers A form of acquired immunity in which the body produces its
own antibodies against disease-causing antigens.
Usually permanent and may be acquired from:
- Surviving infection
- Vaccination
Passive immunity correct answers Immunity conferred by transferring antibodies from an
individual who is immune to a pathogen to another individual
____________________ use the *killed version* of a virus or bacteria that causes the disease
correct answers Inactivated vaccines
What is a limitation of inactivated vaccines? correct answers Immunity isn't as strong; therefore,
booster may be required for ongoing immunity
Types of inactivated vaccines correct answers - Polysaccharide *(do not produce a good immune
response in children less than 2 yrs)*, ex. Pneumovax 23
- Conjugate (polysaccharide from bacteria binds to carrier proteins), increases immune response
in infants, ex. Prevnar 13, Hib, and Meningococcal
- Recombinant (gene segment insertion), ex. Gardasil, Influenza, Flubok Quadrivalent
___________________ are most similar to the actual disease and provide a strong, long-lasting
immune response correct answers Live attenuated (weaker) vaccines
, Made from viruses or bacteria; must replicate to work, produce strong immune response
What is a C/I in a *live vaccine*? correct answers Patients who are *immunocompromised and
pregnant*; circulating antibodies can interfere with vaccine replication
Live vaccine acronym correct answers *COZY IV RM*
C = Cholera
O = Oral Typhoid
Z = Zoster (Zostavax) - no longer available
Y = Yellow Fever
I = Intranasal Influenza
V = Varicella
R = Rotavirus
M = MMR
Vaccines can be given _________________________ correct answers simultaneously
Note: lives can also be separated 4 weeks apart
Live vaccines and antibody correct answers
Live vaccines and TB skin test (TST) correct answers Live vaccines can cause a false negative
TST result. There are *3 options* to reduces this risk (see p. 311)
Where are vaccine AEs reported? correct answers VAERS!
Annual influenza vaccine is for all special groups greater than or equal to what age? correct
answers 6 months!
VACCINATIONS FOR SPECIFIC POPS: PREGGERS correct answers - Influenza, inactivated
(during any trimester)
- Tdap x with *each pregnancy* (weeks 27-36 optimally), make sure those in close contact with
baby get the vaccine
VACCINATIONS FOR SPECIFIC POPS: ASPLENIA correct answers - Hib
- Pneumo vaccines (Prevnar 13 and Pneumovax 23)
- Meningococcal
VACCINATIONS FOR SPECIFIC POPS: IMMUNODEFICIENCY correct answers - Pneumo
vaccines (Prevnar 13 and Pneumovax 23)
If have HIV:
- Meningococcal conjugate
