Question 1
pts
Adherence is improved when a drug can be given once daily. Which of the following oral
cholinestesterase inhibitors can be given once daily?
Donepezil (Aricept).
Pyridostigmine (Mestinon).
Tacrine (Cognex).
Rivastigmine (Exelon).
The dosing schedules of neostigmine and pyridostigmine are similar. Donepezil has a
once-daily dosing regimen. Galantamine, rivastigmine, and memantine are all 2 times a
day doses, but galantamine is available in extended-release capsules that are dosed
once daily. Rivastigmine can also be dosed once daily in the transdermal patch form.
Tacrine requires four daily doses and is most effective on an empty stomach, which
results in the doses being adjusted for meals. For patients who are older adults and
who have a disease process that includes memory problems, or for patients whose
caregivers are also older adults, this complex regimen may present adherence
problems
Question 2
pts
A 65-year-old male has been diagnosed with hypertension and benign prostatic
hyperplasia (BPH). Doxazosin (Cardura) was prescribed to treat his hypertension and
his BPH symptoms have improved. Why?