Principles, Casework Applications &
Postmortem Analysis (Lectures 1–5)|
Complete Verified Questions
Provided with A+ Graded Rationales
Latest Updated 2026
What is forensic toxicology?
The application of toxicology for the purposes of the law
What are the 3 main sub-disciplines of forensic tox?
1. human performance
2. postmortem forensic tox
3. forensic drug testing (employment)
What is the difference between a forensic toxicologist and a drug chemist?
drug chemist deals with seized drugs and toxicologist deals with drugs and poisons in
biological specimens
What are the 6 main casework applications for forensic tox?
1. unknown drug ID
2. sexual assault
3. homicide
4. suicide
5. accidental
6. unexplained death
What are the 6 steps of the methodology for forensic tox?
1. isolation (from matrix)
2. concentration
3. identification
4. confirmation
5. quantification
6. interpretation (of analytical findings)
, What are the 4 types of manner of death?
1. homicide
2. accidental
3. natural
4. suicide
Unknown cause of death will eventually
be categorized as one of the 4 manners of death
What can pulmonary congestion/edema be a good indicator of?
an overdose
With death attributed to drug use, what would one want to differentiate between?
suicide and accidental death
What specimen is the gold standard in postmortem tox?
blood bc it is very indicative of the body's condition at the time of death
What is a disadvantage of testing blood in postmortem cases?
subject to redistribution effects
What is an advantage of testing vitreous humor in postmortem cases?
anatomically isolated, resistant to putrefaction/decomp
What is a disadvantage of testing vitreous humor in postmortem cases?
there is a lag between VH and blood
What is an advantage of testing the liver in postmortem cases?
can be used when minimal blood is available
What is a disadvantage of testing the liver in postmortem cases?
high concentrations of drugs and are hard to quantify
What is a disadvantage of testing urine in postmortem cases?
long window of detection shows drug use hours-days prior to death (not necessarily at TOD)
Which specimen has the longest window of detection?
hair