NURS 323 Pharm Quiz 1 Practice Qs With
Complete Solutions
Place the following routes of medication administration in order of most bioavailable to
least bioavailable: IM/SQ, PO, IV - ANSWER Most: IV
IM/SQ
Least: PO
Which drug needs special transport across a cell membrane in order to be effective?
a) Lipid soluble meds and ionized
b) Water soluble meds and non-ionized - ANSWER b) Water soluble meds and
non-ionized
Mr. Jones is taking drug A which is metabolized by the CYP3A4 enzyme in the liver. He
loves to drink grapefruit juice which is a known inhibitor of that enzyme. If this inhibits
the enzyme, will the patient have higher levels of the drug in the body or lower levels of
the drug? - ANSWER Higher levels of the drug
Mrs. Smith is taking drug C which is metabolized by the CYP3A4 enzyme in the liver. She
just started on drug D which is a known inducer of that enzyme. If this induces the
enzyme, will the patient have higher levels of drug C in the body or lower levels of drug C
in the body? - ANSWER Lower levels of drug C
Drug X has a narrow therapeutic range of 1-3. What does that mean for safety
implications? - ANSWER Less safe
Drug H has a half life of 2 days. When a patient starts taking this medication it will take
_____ to _____ days to reach plateau. - ANSWER 8 to 10
Providers may prescribe loading and maintenance doses of some drugs to achieve
plateau faster. The nurse knows the loading dose will be _____ and the maintenance
, dose will be _____. (Lower or higher) - ANSWER Loading dose will be higher and the
maintenance dose will be lower.
Drug Y mimics the action of endogenous hormone T filling the receptors which makes it
a(n):
a) Agonist
b) Antagonist - ANSWER a) Agonist
If an antagonist is constantly blocking a receptor, does that make the receptor more or
less sensitive when it is eventually filled by the agonist? - ANSWER More sensitive
A patient has been taking a brand-name drug, which is now being changed to generic.
The patient asks the nurse if he should pay out of his pocket to continue receiving the
brand name drug. Your response is:
a) Generic drugs have the same active ingredients as their brand name equivalent
b) Trade name drugs contain different active ingredients than generic drugs
c) Generic meds can be absorbed differently
d) Brand name drugs are worth the price difference because they work better -
ANSWER a) Generic drugs have the same active ingredients as their brand name
equivalent
Which of the following pharmacological categories is the safest in pregnancy?
a) Category X
b) Category B
c) Category C
d) Category D - ANSWER b) Category B
Complete Solutions
Place the following routes of medication administration in order of most bioavailable to
least bioavailable: IM/SQ, PO, IV - ANSWER Most: IV
IM/SQ
Least: PO
Which drug needs special transport across a cell membrane in order to be effective?
a) Lipid soluble meds and ionized
b) Water soluble meds and non-ionized - ANSWER b) Water soluble meds and
non-ionized
Mr. Jones is taking drug A which is metabolized by the CYP3A4 enzyme in the liver. He
loves to drink grapefruit juice which is a known inhibitor of that enzyme. If this inhibits
the enzyme, will the patient have higher levels of the drug in the body or lower levels of
the drug? - ANSWER Higher levels of the drug
Mrs. Smith is taking drug C which is metabolized by the CYP3A4 enzyme in the liver. She
just started on drug D which is a known inducer of that enzyme. If this induces the
enzyme, will the patient have higher levels of drug C in the body or lower levels of drug C
in the body? - ANSWER Lower levels of drug C
Drug X has a narrow therapeutic range of 1-3. What does that mean for safety
implications? - ANSWER Less safe
Drug H has a half life of 2 days. When a patient starts taking this medication it will take
_____ to _____ days to reach plateau. - ANSWER 8 to 10
Providers may prescribe loading and maintenance doses of some drugs to achieve
plateau faster. The nurse knows the loading dose will be _____ and the maintenance
, dose will be _____. (Lower or higher) - ANSWER Loading dose will be higher and the
maintenance dose will be lower.
Drug Y mimics the action of endogenous hormone T filling the receptors which makes it
a(n):
a) Agonist
b) Antagonist - ANSWER a) Agonist
If an antagonist is constantly blocking a receptor, does that make the receptor more or
less sensitive when it is eventually filled by the agonist? - ANSWER More sensitive
A patient has been taking a brand-name drug, which is now being changed to generic.
The patient asks the nurse if he should pay out of his pocket to continue receiving the
brand name drug. Your response is:
a) Generic drugs have the same active ingredients as their brand name equivalent
b) Trade name drugs contain different active ingredients than generic drugs
c) Generic meds can be absorbed differently
d) Brand name drugs are worth the price difference because they work better -
ANSWER a) Generic drugs have the same active ingredients as their brand name
equivalent
Which of the following pharmacological categories is the safest in pregnancy?
a) Category X
b) Category B
c) Category C
d) Category D - ANSWER b) Category B
