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HESI Medical-Surgical Practice Exam 2025 | Comprehensive Nursing Review with Verified Questions & Answers With Rationales

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Prepare to excel on your HESI Medical-Surgical Nursing exam with this comprehensive practice exam and study guide. Designed for BSN, LPN/LVN, and pre-licensure nursing students, this resource provides a structured approach to mastering medical-surgical nursing content, critical thinking, and clinical decision-making skills. This practice exam contains realistic, exam-style questions with fully verified answers, carefully aligned with current HESI testing standards (2025)

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HESI - MEDICAL SURGICAL PRACTICE EXAM
1. The nurse is assessing a client's laboratory values following administration

of chemotherapy. Which lab value leads the nurse to suspect that the client is

experiencing tumor lysis syndrome (TLS)?


A. Serum PTT of 10 seconds




B. Serum calcium of 5 mg/dl




C. Oxygen saturation of 90%




D. Hemoglobin of 10 g/dl

Answer B. Serum calcium of 5 mg/dl.




TLS results in hyperkalemia, hypocalcemia, hyperuricemia, and hyperphosphatemia.



,2. A client is admitted to the hospital with a diagnosis of severe acute divertic-

ulitis. Which assessment finding should the nurse expect this client to exhibit?



A. Lower left quadrant pain and a low-grade fever




B. Severe pain at McBurney's point and nausea.




C. Abdominal pain and intermittent tenesmus




D. Exacerbations of severe diarrhea

Answer A. Lower left quadrant pain and a low-grade fever.




Left lower quadrant pain occurs with diverticulitis because the sigmoid colon is the most common area for diverticula,

and the inflammation of diverticula causes a low-grade fever.

3. During CPR, when attempting to ventilate a client's lungs, the nurse notes

that the chest is not moving. What action should the nurse take first?


,A. Use a laryngoscope to check for a foreign body lodged in the esophagus.




B. Reposition the head to validate that the head is in the proper position to

open the airway.






, C. Turn the client to the side and administer three back blows.




D. Perform a finger sweep of the mouth to remove any vomitus

Answer B. Reposition the head to validate that the head is in the proper position to open the airway.



The most frequent cause of inadequate aeration of the client's lungs during CPR is improper positioning of the head

resulting in occlusion of the airway. A foreign body can occlude the airway, but this is not common unless choking

preceded the cardiac emergency, and should not be the nurse's first action.

4. A client is admitted to the hospital with a medical diagnosis of pneumo-

coccal pneumonia. The nurse knows that the prognosis for gram-negative

pneumonias (such as E. coli, Klebsiella, Pseudomonas, and Proteus) is very poor

because




A. They occur in the lower love alveoli which are more sensitive to infection

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