PSYCHOPHARMACOLOGY UPDATED SCRIPTED EXAM
QUESTIONS AND SOLUTIONS GUARANTEE A+
✔✔What are the AE of Valproate? - ✔✔Sedation, hepatotoxicity, cognitive dulling,
teratogenic (NTD)
✔✔What are the AE of Carbamazapine? - ✔✔Hepatotoxicity (monitor LFTs),
agranulocytosis (monitor CBCs), sedation
✔✔What drugs are first-line for patients with insomnia? - ✔✔BZP-like hypnotics -
Zolpidem [Ambien], Zapelon [Sonata], Eszopiclone [Lunesta] - best for staying asleep
*Act on "sleep gates" of GABA receptors
✔✔What BZPs are the best to use in patients w/ liver dysfunction? - ✔✔Drugs
metabolized "Outside The Liver" - Oxazepam, Temazepam, Lorazepam
✔✔What is the MOA of BZPs? - ✔✔Potentiate GABA receptor - Increase the frequency
of GABA(a) Chloride channel opening
✔✔What BZPs are primarily used to tx panic attacks and status epilepticus? -
✔✔Midazolam [Versed], Lorazepam [Ativan], Diazepam [Valium]
*Fast acting, short duration
✔✔What is the antidote for BZPs OD? - ✔✔Flumazenil
✔✔What is the treatment of choice for insomnia? - ✔✔BEHAVIOR CHANGES
✔✔ What is the MOA of antipsychotics? - ✔✔Dopamine receptor antagonists
✔✔What are the two classes of antipsychotics? - ✔✔Typicals - antagonize D2 only,
greater risk of side effects
Atypicals - antagonize D2, D4, and 5HTZ, favorable for long term treatment
*Risperidone [Risperdal] - atypical, only acts on D2 and 5HTz
✔✔Typical Antipsychotic Rx - ✔✔Haloperidol [Haldol], Chlorpromazine [Thorazine],
Prochlorperazine [Compazine], Fluphenazine [Prolixin]
✔✔Atypical Antipsychotic Rx - ✔✔Risperidone [Risperdal]
Olanzapine [Zyprexa]
Quetiapine [Seroquel]
Clozapine [Clozaril]
Ziprasidone [Geodon]
Aripiprazole [Abilify]
QUESTIONS AND SOLUTIONS GUARANTEE A+
✔✔What are the AE of Valproate? - ✔✔Sedation, hepatotoxicity, cognitive dulling,
teratogenic (NTD)
✔✔What are the AE of Carbamazapine? - ✔✔Hepatotoxicity (monitor LFTs),
agranulocytosis (monitor CBCs), sedation
✔✔What drugs are first-line for patients with insomnia? - ✔✔BZP-like hypnotics -
Zolpidem [Ambien], Zapelon [Sonata], Eszopiclone [Lunesta] - best for staying asleep
*Act on "sleep gates" of GABA receptors
✔✔What BZPs are the best to use in patients w/ liver dysfunction? - ✔✔Drugs
metabolized "Outside The Liver" - Oxazepam, Temazepam, Lorazepam
✔✔What is the MOA of BZPs? - ✔✔Potentiate GABA receptor - Increase the frequency
of GABA(a) Chloride channel opening
✔✔What BZPs are primarily used to tx panic attacks and status epilepticus? -
✔✔Midazolam [Versed], Lorazepam [Ativan], Diazepam [Valium]
*Fast acting, short duration
✔✔What is the antidote for BZPs OD? - ✔✔Flumazenil
✔✔What is the treatment of choice for insomnia? - ✔✔BEHAVIOR CHANGES
✔✔ What is the MOA of antipsychotics? - ✔✔Dopamine receptor antagonists
✔✔What are the two classes of antipsychotics? - ✔✔Typicals - antagonize D2 only,
greater risk of side effects
Atypicals - antagonize D2, D4, and 5HTZ, favorable for long term treatment
*Risperidone [Risperdal] - atypical, only acts on D2 and 5HTz
✔✔Typical Antipsychotic Rx - ✔✔Haloperidol [Haldol], Chlorpromazine [Thorazine],
Prochlorperazine [Compazine], Fluphenazine [Prolixin]
✔✔Atypical Antipsychotic Rx - ✔✔Risperidone [Risperdal]
Olanzapine [Zyprexa]
Quetiapine [Seroquel]
Clozapine [Clozaril]
Ziprasidone [Geodon]
Aripiprazole [Abilify]
