OpenStax Microbiology Test Bank
Chapter 19: Diseases of the Immune System
Chapter 19: Diseases of the Immune System
* = Correct answer
Multiple Choice
1. An allergy is an example of which of the following?
A. a type I hypersensitivity*
B. a type II hypersensitivity
C. a type III hypersensitivity
D. a type IV hypersensitivity
Difficulty: Easy
ASM Standard: N/A
2. If someone were accidentally given blood of the wrong type, which of the following is likely
to occur?
A. an autoimmune disorder
B. anaphylaxis
C. a hemolytic transfusion reaction*
D. a type I hypersensitivity
Difficulty: Easy
ASM Standard: N/A
3. Granules in mast cells are released to the extracellular environment through which of the
following processes?
A. an Arthus reaction
B. anaphylaxis
C. degranulation*
D. the hemolytic response
Difficulty: Easy
ASM Standard: N/A
4. The term immune tolerance means which of the following?
A. becoming sensitized with repeated exposures
B. developing autoimmune disease after repeated exposures
C. having an unusually weak immune response to common antigens
D. the ability to recognize self and prevent immune attack on one’s own cell*
Difficulty: Easy
ASM Standard: N/A
5. Desensitization treatment is also known by which of the following terms?
A. allografting
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,OpenStax Microbiology Test Bank
Chapter 19: Diseases of the Immune System
B. autoimmunity
C. hyposensitization therapy*
D. serum treatment
Difficulty: Easy
ASM Standard: N/A
6. A granuloma is which of the following infections?
A. acute systemic infection
B. chronic local infection*
C. chronic systemic infection
D. disseminated infection
Difficulty: Easy
ASM Standard: N/A
7. Rh factors are which of the following?
A. a type of T cell
B. important examples of immune cells
C. important RBC antigens*
D. unimportant in blood transfusions
Difficulty: Easy
ASM Standard: N/A
8. Serum sickness is which of the following?
A. systemic type I hypersensitivity
B. systemic type II hypersensitivity
C. systemic type III hypersensitivity*
D. systemic type IV hypersensitivity
Difficulty: Easy
ASM Standard: N/A
9. Which of the following types of transplants has the lowest risk of rejection?
A. allograft
B. autograft*
C. isograft
D. xenograft
Difficulty: Moderate
ASM Standard: N/A
10. Which of the following types of infection is most common in an individual with X-linked
agammaglobulinemia?
A. infections associated with autoimmune inflammations
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, OpenStax Microbiology Test Bank
Chapter 19: Diseases of the Immune System
B. infections caused by extracellular, pyogenic pathogens*
C. infections caused by intracellular pathogens
D. viral infections
Difficulty: Moderate
ASM Standard: N/A
11. In some cases, transplanted tissue (such as bone marrow) can produce cytotoxic T cells that
attack the host cells of the recipient. Which of the following describes such an attack?
A. a hemolytic transfusion reaction
B. an autograft reaction
C. graft versus host disease*
D. transplant rejection
Difficulty: Moderate
ASM Standard: N/A
12. Which of the following is an advantage of using vaccines instead of antibacterial sera, such
as the diphtheria antitoxin?
A. Antitoxins are less likely to cause type I hypersensitivity.
B. Antitoxins are more likely to cause the disease they are intended to treat.
C. Vaccines are less likely to cause systemic type III hypersensitivity.*
D. Vaccines are less likely to cause type II hypersensitivity.
Difficulty: Moderate
ASM Standard: N/A
13. Which of the following is an example of a CD4 Th1-mediated reaction?
A. anaphylactic reaction
B. chronic asthma
C. delayed type hypersensitivity*
D. transplant rejection
Difficulty: Moderate
ASM Standard: N/A
14. Contact dermatitis is an example of which of the following?
A. CD4 TH1-mediated reaction*
B. CD4 TH2-mediated reaction
C. type of serum sickness
D. underdeveloped immune response
Difficulty: Moderate
ASM Standard: N/A
Page 3 of 18
Chapter 19: Diseases of the Immune System
Chapter 19: Diseases of the Immune System
* = Correct answer
Multiple Choice
1. An allergy is an example of which of the following?
A. a type I hypersensitivity*
B. a type II hypersensitivity
C. a type III hypersensitivity
D. a type IV hypersensitivity
Difficulty: Easy
ASM Standard: N/A
2. If someone were accidentally given blood of the wrong type, which of the following is likely
to occur?
A. an autoimmune disorder
B. anaphylaxis
C. a hemolytic transfusion reaction*
D. a type I hypersensitivity
Difficulty: Easy
ASM Standard: N/A
3. Granules in mast cells are released to the extracellular environment through which of the
following processes?
A. an Arthus reaction
B. anaphylaxis
C. degranulation*
D. the hemolytic response
Difficulty: Easy
ASM Standard: N/A
4. The term immune tolerance means which of the following?
A. becoming sensitized with repeated exposures
B. developing autoimmune disease after repeated exposures
C. having an unusually weak immune response to common antigens
D. the ability to recognize self and prevent immune attack on one’s own cell*
Difficulty: Easy
ASM Standard: N/A
5. Desensitization treatment is also known by which of the following terms?
A. allografting
Page 1 of 18
,OpenStax Microbiology Test Bank
Chapter 19: Diseases of the Immune System
B. autoimmunity
C. hyposensitization therapy*
D. serum treatment
Difficulty: Easy
ASM Standard: N/A
6. A granuloma is which of the following infections?
A. acute systemic infection
B. chronic local infection*
C. chronic systemic infection
D. disseminated infection
Difficulty: Easy
ASM Standard: N/A
7. Rh factors are which of the following?
A. a type of T cell
B. important examples of immune cells
C. important RBC antigens*
D. unimportant in blood transfusions
Difficulty: Easy
ASM Standard: N/A
8. Serum sickness is which of the following?
A. systemic type I hypersensitivity
B. systemic type II hypersensitivity
C. systemic type III hypersensitivity*
D. systemic type IV hypersensitivity
Difficulty: Easy
ASM Standard: N/A
9. Which of the following types of transplants has the lowest risk of rejection?
A. allograft
B. autograft*
C. isograft
D. xenograft
Difficulty: Moderate
ASM Standard: N/A
10. Which of the following types of infection is most common in an individual with X-linked
agammaglobulinemia?
A. infections associated with autoimmune inflammations
Page 2 of 18
, OpenStax Microbiology Test Bank
Chapter 19: Diseases of the Immune System
B. infections caused by extracellular, pyogenic pathogens*
C. infections caused by intracellular pathogens
D. viral infections
Difficulty: Moderate
ASM Standard: N/A
11. In some cases, transplanted tissue (such as bone marrow) can produce cytotoxic T cells that
attack the host cells of the recipient. Which of the following describes such an attack?
A. a hemolytic transfusion reaction
B. an autograft reaction
C. graft versus host disease*
D. transplant rejection
Difficulty: Moderate
ASM Standard: N/A
12. Which of the following is an advantage of using vaccines instead of antibacterial sera, such
as the diphtheria antitoxin?
A. Antitoxins are less likely to cause type I hypersensitivity.
B. Antitoxins are more likely to cause the disease they are intended to treat.
C. Vaccines are less likely to cause systemic type III hypersensitivity.*
D. Vaccines are less likely to cause type II hypersensitivity.
Difficulty: Moderate
ASM Standard: N/A
13. Which of the following is an example of a CD4 Th1-mediated reaction?
A. anaphylactic reaction
B. chronic asthma
C. delayed type hypersensitivity*
D. transplant rejection
Difficulty: Moderate
ASM Standard: N/A
14. Contact dermatitis is an example of which of the following?
A. CD4 TH1-mediated reaction*
B. CD4 TH2-mediated reaction
C. type of serum sickness
D. underdeveloped immune response
Difficulty: Moderate
ASM Standard: N/A
Page 3 of 18
