DISEASE
8TH EDITION
• AUTHOR(S)KEVIN PATTON
TEST BANK
Reference
Ch. 1 — Introduction to the body — Language of science &
levels of organization
Question Stem
A lab partner claims that because a molecule functions
properly, the tissue and organ formed from it will automatically
function normally. Which critique best applies using levels of
organization?
A. Molecule → tissue → organ is linear; dysfunction at the
cellular level never affects organs.
,B. Structure–function interactions are hierarchical; emergent
properties at higher levels can modify function.
C. Tissues determine molecules; molecular structure is
irrelevant if tissue organization is correct.
D. Organ systems function independently, so molecular
problems are isolated.
Correct Answer
B
Rationales
Correct (B): Higher levels (cells → tissues → organs) show
emergent properties; normal molecular function contributes
but does not guarantee organ-level function because
organization and interactions matter.
Incorrect (A): False — dysfunction at molecular/cellular levels
often impairs tissues and organs.
Incorrect (C): Reverses causality; molecular structure often
constrains tissue/organ function.
Incorrect (D): Organs interact within systems; molecular issues
can propagate across systems.
Teaching Point
Higher-level function depends on organization and interactions,
not molecules alone.
Citation
Patton, K. T. (2024). The Human Body in Health & Disease (8th
ed.). Ch. 1.
, 2.
Reference
Ch. 1 — Introduction to the body — Scientific method
Question Stem
A researcher hypothesizes that a new temperature change
protocol will change enzyme activity in cultured cells. Which
step best tests causation rather than correlation?
A. Measure enzyme activity in existing cultures with varying
temperatures and compare.
B. Form a hypothesis stating temperature affects activity.
C. Manipulate temperature in an experimental group while
keeping other variables constant and measure enzyme activity.
D. Review literature that reports temperature differences and
enzyme levels.
Correct Answer
C
Rationales
Correct (C): Experimental manipulation with controlled
variables allows inference of causation.
Incorrect (A): Observational comparisons can show correlation
but not causation due to confounders.
Incorrect (B): Forming a hypothesis is necessary but does not
test causation.
, Incorrect (D): Literature review provides background but not
direct causal testing in the current system.
Teaching Point
Controlled manipulation is required to infer causation in
experiments.
Citation
Patton, K. T. (2024). The Human Body in Health & Disease (8th
ed.). Ch. 1.
3.
Reference
Ch. 1 — Introduction to the body — Anatomical position &
anatomical directions
Question Stem
A patient lies supine with palms facing upward. A nurse
documents a bruise on the patient’s “anteromedial” forearm.
Which area best matches that description?
A. The back (posterior) and lateral surface of the forearm.
B. The front (anterior) surface toward the midline of the
forearm.
C. The front surface on the outer edge of the forearm.
D. The palm side near the wrist crease only.
Correct Answer
B