Introduction to Behavioral Neuroscience Instructor Answer Guide
Multiple Choice
14.1 Basic Principles of Pharmacology
1. In some situations, it is preferable for medication to be active only during certain times
of the day. Which characteristic of the drug would be most useful in preventing unwanted
extended effects of the drug?
a. A drug delivered via transdermal patch
b. A drug with a short half-life
c. A drug with a long half-life
d. A large dose of a drug
Answer: b
2. First pass-metabolism occurs with which route of administration?
a. Inhalation
b. Intranasal
c. Intravenous
d. Oral
Answer: d
3. Which route of administration results in the fastest onset of action?
a. Oral
b. Intranasal
c. Intravenous
d. Transdermal
Answer: c
4. What type of drug is most likely to cross the blood-brain barrier?
a. Large molecule
b. Positively charged molecule
c. Small molecule
d. Non-lipid soluble
Answer: c
5. Which type of receptor is primarily responsible for fast synaptic transmission?
a. Ionotropic receptor
b. Metabotropic receptor
c. G-protein coupled receptor
, d. Kinase receptor
Answer: a
6. Which of the following would have the lowest receptor response with increasing dose?
a. Full agonist
b. Inverse agonist
c. Antagonist
d. Partial agonist
Answer: b
7. What does the term binding affinity refer to?
a. The concentration of neurotransmitter in the synapse
b. The ability of a drug to cross the blood-brain barrier
c. The rate at which a drug is metabolized in the body
d. The strength of the interaction between a drug and target receptor
Answer: d
8. Which of the following best describes the therapeutic window of a drug?
a. The range of doses in which a drug is both safe and effective
b. The time it takes for a drug to completely metabolize in the body
c. The minimum tolerated dose of a drug
d. The time it takes for a drug to produce its maximum effect
Answer: a
9. Which of the following statements about g-protein coupled receptors is false?
a. When activated they can stimulate intracellular signaling
b. They are also known as metabotropic receptors
c. The receptor itself is an ion channel that is activated by the binding of a ligand
d. The effects of receptor activation are slow-acting
Answer: c
14.2 Psychotherapeutics
10. What does the microdialysis technique allow you to measure?
a. The electrical activity of neurons
b. The amount of neurotransmitter release
c. The structural integrity of white matter
d. The expression of a specific genes
Answer: b
2
Updated October 2024
Multiple Choice
14.1 Basic Principles of Pharmacology
1. In some situations, it is preferable for medication to be active only during certain times
of the day. Which characteristic of the drug would be most useful in preventing unwanted
extended effects of the drug?
a. A drug delivered via transdermal patch
b. A drug with a short half-life
c. A drug with a long half-life
d. A large dose of a drug
Answer: b
2. First pass-metabolism occurs with which route of administration?
a. Inhalation
b. Intranasal
c. Intravenous
d. Oral
Answer: d
3. Which route of administration results in the fastest onset of action?
a. Oral
b. Intranasal
c. Intravenous
d. Transdermal
Answer: c
4. What type of drug is most likely to cross the blood-brain barrier?
a. Large molecule
b. Positively charged molecule
c. Small molecule
d. Non-lipid soluble
Answer: c
5. Which type of receptor is primarily responsible for fast synaptic transmission?
a. Ionotropic receptor
b. Metabotropic receptor
c. G-protein coupled receptor
, d. Kinase receptor
Answer: a
6. Which of the following would have the lowest receptor response with increasing dose?
a. Full agonist
b. Inverse agonist
c. Antagonist
d. Partial agonist
Answer: b
7. What does the term binding affinity refer to?
a. The concentration of neurotransmitter in the synapse
b. The ability of a drug to cross the blood-brain barrier
c. The rate at which a drug is metabolized in the body
d. The strength of the interaction between a drug and target receptor
Answer: d
8. Which of the following best describes the therapeutic window of a drug?
a. The range of doses in which a drug is both safe and effective
b. The time it takes for a drug to completely metabolize in the body
c. The minimum tolerated dose of a drug
d. The time it takes for a drug to produce its maximum effect
Answer: a
9. Which of the following statements about g-protein coupled receptors is false?
a. When activated they can stimulate intracellular signaling
b. They are also known as metabotropic receptors
c. The receptor itself is an ion channel that is activated by the binding of a ligand
d. The effects of receptor activation are slow-acting
Answer: c
14.2 Psychotherapeutics
10. What does the microdialysis technique allow you to measure?
a. The electrical activity of neurons
b. The amount of neurotransmitter release
c. The structural integrity of white matter
d. The expression of a specific genes
Answer: b
2
Updated October 2024
