Introduction to Behavioral Neuroscience
OpenStax
Chapter 3: Basic Neurochemistry
Multiple Choice
1. Dopamine neurons within the ________ project to the ________.
A. substantia nigra / neocortex
B. ventral tegmental area / basal ganglia
C. locus coeruleus / neocortex
D. ventral tegmental area / limbic system and cortex*
Bloom’s Level 1. Remembering
2. The most important feature of the blood-brain barrier, with regards to neurochemistry, is:
A. it possesses a variety of specialized nutrient transporting mechanisms.*
B. it blocks the entry of water into the brain.
C. it is composed primarily of proteins.
D. it is very permeable to amino acids.
Bloom’s Level 2. Understanding
3. Which of the following is not an amine containing neurotransmitter?
A. Dopamine
B. Acetylcholine*
C. Serotonin
D. Dopamine
Bloom’s Level 1. Remembering
4. The addition of a(n) ________ molecule to the benzene ring of ________ produces
________.
A. hydroxyl / tryptophan / L-DOPA
B. oxygen / tyrosine / dopamine
C. hydroxyl / tyrosine / L-DOPA*
D. oxygen / tryptophan / dopamine
Bloom’s Level 1. Remembering
5. Copper is a required co-factor for the enzyme:
A. dopamine-beta-hydroxylase.*
B. DOPA decarboxylase.
C. tyrosine hydroxylase.
D. monoamine oxidase.
1
, Introduction to Behavioral Neuroscience
OpenStax
Bloom’s Level 1. Remembering
6. After dopamine and norepinephrine are released from axonal terminal, which of the
following does not happen?
A. They bind to specialized protein receptors on both the pre- and post-synaptic
membranes.
B. Most of the molecules are re-absorbed by the axonal terminal by both low- and high-
capacity high-affinity transporters.
C. Most of the neurotransmitter molecules are destroyed by enzymes in the synapse.*
D. Some of the molecules diffuse away from the synapse.
Bloom’s Level 2. Understanding
7. Under normal aerobic conditions, dopamine will be catabolized by ________ and ultimately
excreted in the urine as ________.
A. monoamine oxidase / HVA*
B. catechol-O-methyltransferase / 3-MT
C. dihydroxyphenylacetase, DOPAC
D. monoamine oxidase, MHPG
Bloom’s Level 2. Understanding
8. Dopamine neurons that originate in the ________ project to the ________.
A. floor of the 4th ventricle / cortex and basal ganglia
B. Raphe nuclei / brainstem and cortex
C. ventral tegmentum / basal ganglia and frontal lobes*
D. basal forebrain / thalamus and frontal lobes
Bloom’s Level 1. Remembering
9. The dopamine pathway that projects to the limbic system is associated with ________.
A. learning and memory
B. the control of movement
C. the control of emotion*
D. the control of the feeding centers
Bloom’s Level 2. Understanding
10. Although an imbalance of dopamine release underlies the symptoms associated with
psychosis, the direct cause of psychosis a dysfunction of _______ receptors.
A. acetylcholine
B. dopamine
C. glutamate*
D. serotonin
2
OpenStax
Chapter 3: Basic Neurochemistry
Multiple Choice
1. Dopamine neurons within the ________ project to the ________.
A. substantia nigra / neocortex
B. ventral tegmental area / basal ganglia
C. locus coeruleus / neocortex
D. ventral tegmental area / limbic system and cortex*
Bloom’s Level 1. Remembering
2. The most important feature of the blood-brain barrier, with regards to neurochemistry, is:
A. it possesses a variety of specialized nutrient transporting mechanisms.*
B. it blocks the entry of water into the brain.
C. it is composed primarily of proteins.
D. it is very permeable to amino acids.
Bloom’s Level 2. Understanding
3. Which of the following is not an amine containing neurotransmitter?
A. Dopamine
B. Acetylcholine*
C. Serotonin
D. Dopamine
Bloom’s Level 1. Remembering
4. The addition of a(n) ________ molecule to the benzene ring of ________ produces
________.
A. hydroxyl / tryptophan / L-DOPA
B. oxygen / tyrosine / dopamine
C. hydroxyl / tyrosine / L-DOPA*
D. oxygen / tryptophan / dopamine
Bloom’s Level 1. Remembering
5. Copper is a required co-factor for the enzyme:
A. dopamine-beta-hydroxylase.*
B. DOPA decarboxylase.
C. tyrosine hydroxylase.
D. monoamine oxidase.
1
, Introduction to Behavioral Neuroscience
OpenStax
Bloom’s Level 1. Remembering
6. After dopamine and norepinephrine are released from axonal terminal, which of the
following does not happen?
A. They bind to specialized protein receptors on both the pre- and post-synaptic
membranes.
B. Most of the molecules are re-absorbed by the axonal terminal by both low- and high-
capacity high-affinity transporters.
C. Most of the neurotransmitter molecules are destroyed by enzymes in the synapse.*
D. Some of the molecules diffuse away from the synapse.
Bloom’s Level 2. Understanding
7. Under normal aerobic conditions, dopamine will be catabolized by ________ and ultimately
excreted in the urine as ________.
A. monoamine oxidase / HVA*
B. catechol-O-methyltransferase / 3-MT
C. dihydroxyphenylacetase, DOPAC
D. monoamine oxidase, MHPG
Bloom’s Level 2. Understanding
8. Dopamine neurons that originate in the ________ project to the ________.
A. floor of the 4th ventricle / cortex and basal ganglia
B. Raphe nuclei / brainstem and cortex
C. ventral tegmentum / basal ganglia and frontal lobes*
D. basal forebrain / thalamus and frontal lobes
Bloom’s Level 1. Remembering
9. The dopamine pathway that projects to the limbic system is associated with ________.
A. learning and memory
B. the control of movement
C. the control of emotion*
D. the control of the feeding centers
Bloom’s Level 2. Understanding
10. Although an imbalance of dopamine release underlies the symptoms associated with
psychosis, the direct cause of psychosis a dysfunction of _______ receptors.
A. acetylcholine
B. dopamine
C. glutamate*
D. serotonin
2
