ADVANCED PHARMACOLOGY FOR PRESCRIBERS: CORE CONCEPTS (1ST EDITION)

ADVANCED PHARMACOLOGY FOR
PRESCRIBERS: CORE CONCEPTS (1ST
EDITION)

◉ The science of pharmaceutical systems/ preparations. Answer:
Pharmaceutics


◉ What the body does to drugs. Answer: Pharmacokinetics


◉ What the drugs do to the body. Answer: Pharmacodynamics


◉ Treatment of disease with drugs. Answer: Pharmacotherapy


◉ Study of drugs, their sources, actions, chemistry and uses. Answer:
Pharmacology


◉ Liberation, Absorption, Distribution, Metabolism, Elimination,
Therapeutic drug monitoring. Answer: Basic pharmacokinetics
(LADMET)


◉ The minimum concentration. Answer: C-min


◉ The maximum concentration. Answer: C-max

, ◉ The time to maximum concentration. Answer: T-max


◉ Half-life. Answer: T-1/2


◉ Area Under drug Vs. Time Curve (Total exposure to drug). Answer:
AUC


◉ Volume of distribution. Answer: Vd


◉ Fraction of drug absorbed into system. Answer: F


◉ Elimination rate constant (eg. hr -1). Answer: k


◉ Clearance (eg. volume/time). Answer: CL


◉ Estimated Creatinine Clearance (approximates GFR). Answer: Cr-
CL-est


◉ Serum creatinine. Answer: S-cr


◉ Steady State Concentration. Answer: C-ss


◉ Name brand vs. generic/ 2 different drugs have the same form and
concentration Within -20 to 25%. Answer: Bioequivalence