Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Nursing Test Bank: Selected Chapters from Harrison's
Principles of Internal Medicine, 22nd Edition
Based on your selected chapters from Volumes 1 & 2, here are
20 high-yield, exam-relevant multiple-choice questions
designed for medical-surgical nursing students.
1. A nurse is reviewing the concept of "patient-centered care"
with a student. Which of the following best describes the core
principle of this approach, as it forms the foundation of modern
medical practice?
,A. Maximizing the efficiency of diagnostic testing.
B. Applying the latest biomedical technology to all patients.
C. Eliciting and integrating patient preferences, needs, and
values into clinical decisions.
D. Strictly following evidence-based clinical practice guidelines
for every condition.
Answer: C
Rationale: The fundamental principle of patient-centered care
is to respect and respond to individual patient preferences,
needs, and values, ensuring they guide all clinical decisions. This
is a cornerstone of the contemporary practice of medicine as
described in foundational chapters.
Citation: Harrison's Principles of Internal Medicine, 22nd ed.,
Chapter 1: The Practice of Medicine.
2. When providing health promotion education, the nurse
understands that the most significant modifiable factor
contributing to premature mortality in the United States is:
A. Lack of access to tertiary care hospitals.
B. Genetic predisposition to chronic disease.
C. Behavioral and lifestyle choices.
D. Inadequate pharmaceutical research.
Answer: C
Rationale: Harrison's emphasizes that personal behaviors and
lifestyle choices (e.g., smoking, diet, physical inactivity) are the
leading modifiable contributors to premature death,
highlighting the critical role of health promotion and behavioral
counseling in nursing care.
,Citation: Harrison's Principles of Internal Medicine, 22nd ed.,
Chapter 2: Promoting Good Health.
3. A nurse is counseling a parent who is hesitant about routine
childhood vaccinations, stating, "I read that vaccines can cause
autism." Which is the nurse's most evidence-based and
effective initial response?
A. "You are required by law to vaccinate your child for school
entry."
B. "That information is incorrect. The study suggesting that link
was fraudulent and has been retracted."
C. "I understand you have concerns about your child's safety.
Can you tell me more about what you've read?"
D. "You should trust your doctor; we would never recommend
anything harmful."
Answer: C
Rationale: Effective communication begins with empathy and
seeking to understand the specific concerns. Dismissing the
parent or using authority first can increase defensiveness.
Acknowledging concern and opening a dialogue is the
recommended strategy for addressing vaccine hesitancy.
Citation: Harrison's Principles of Internal Medicine, 22nd ed.,
Chapter 3: Vaccine Opposition and Hesitancy.
4. In clinical decision-making, the concept of "pre-test
probability" is most important for the nurse to understand
because it primarily influences:
A. The cost-effectiveness of a diagnostic test.
, B. The interpretation of a diagnostic test result.
C. The timing of when to administer a medication.
D. The selection of which vital signs to monitor.
Answer: B
Rationale: Pre-test probability (the likelihood of disease before
testing) is crucial for interpreting post-test probability. A test
result (positive or negative) has different meanings in a high-risk
versus a low-risk patient, affecting clinical judgment and next
steps.
Citation: *Harrison's Principles of Internal Medicine, 22nd ed.,
Chapter 4: Decision-Making in Clinical Medicine.*
5. A patient with breast cancer is scheduled for genomic testing
of their tumor. The nurse explains that this is an example of
"precision medicine," which aims to:
A. Provide the same proven treatment to all patients with
breast cancer.
B. Classify disease based on shared anatomical and
symptomatic features.
C. Tailor treatment based on the individual's unique genetic,
biomarker, and phenotypic profile.
D. Focus primarily on cost containment by using the least
expensive therapy first.
Answer: C
Rationale: Precision medicine moves beyond a one-size-fits-all
approach. It uses molecular analysis (like genomic testing) to
match treatments to the specific characteristics of the
individual patient and their disease.
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Nursing Test Bank: Selected Chapters from Harrison's
Principles of Internal Medicine, 22nd Edition
Based on your selected chapters from Volumes 1 & 2, here are
20 high-yield, exam-relevant multiple-choice questions
designed for medical-surgical nursing students.
1. A nurse is reviewing the concept of "patient-centered care"
with a student. Which of the following best describes the core
principle of this approach, as it forms the foundation of modern
medical practice?
,A. Maximizing the efficiency of diagnostic testing.
B. Applying the latest biomedical technology to all patients.
C. Eliciting and integrating patient preferences, needs, and
values into clinical decisions.
D. Strictly following evidence-based clinical practice guidelines
for every condition.
Answer: C
Rationale: The fundamental principle of patient-centered care
is to respect and respond to individual patient preferences,
needs, and values, ensuring they guide all clinical decisions. This
is a cornerstone of the contemporary practice of medicine as
described in foundational chapters.
Citation: Harrison's Principles of Internal Medicine, 22nd ed.,
Chapter 1: The Practice of Medicine.
2. When providing health promotion education, the nurse
understands that the most significant modifiable factor
contributing to premature mortality in the United States is:
A. Lack of access to tertiary care hospitals.
B. Genetic predisposition to chronic disease.
C. Behavioral and lifestyle choices.
D. Inadequate pharmaceutical research.
Answer: C
Rationale: Harrison's emphasizes that personal behaviors and
lifestyle choices (e.g., smoking, diet, physical inactivity) are the
leading modifiable contributors to premature death,
highlighting the critical role of health promotion and behavioral
counseling in nursing care.
,Citation: Harrison's Principles of Internal Medicine, 22nd ed.,
Chapter 2: Promoting Good Health.
3. A nurse is counseling a parent who is hesitant about routine
childhood vaccinations, stating, "I read that vaccines can cause
autism." Which is the nurse's most evidence-based and
effective initial response?
A. "You are required by law to vaccinate your child for school
entry."
B. "That information is incorrect. The study suggesting that link
was fraudulent and has been retracted."
C. "I understand you have concerns about your child's safety.
Can you tell me more about what you've read?"
D. "You should trust your doctor; we would never recommend
anything harmful."
Answer: C
Rationale: Effective communication begins with empathy and
seeking to understand the specific concerns. Dismissing the
parent or using authority first can increase defensiveness.
Acknowledging concern and opening a dialogue is the
recommended strategy for addressing vaccine hesitancy.
Citation: Harrison's Principles of Internal Medicine, 22nd ed.,
Chapter 3: Vaccine Opposition and Hesitancy.
4. In clinical decision-making, the concept of "pre-test
probability" is most important for the nurse to understand
because it primarily influences:
A. The cost-effectiveness of a diagnostic test.
, B. The interpretation of a diagnostic test result.
C. The timing of when to administer a medication.
D. The selection of which vital signs to monitor.
Answer: B
Rationale: Pre-test probability (the likelihood of disease before
testing) is crucial for interpreting post-test probability. A test
result (positive or negative) has different meanings in a high-risk
versus a low-risk patient, affecting clinical judgment and next
steps.
Citation: *Harrison's Principles of Internal Medicine, 22nd ed.,
Chapter 4: Decision-Making in Clinical Medicine.*
5. A patient with breast cancer is scheduled for genomic testing
of their tumor. The nurse explains that this is an example of
"precision medicine," which aims to:
A. Provide the same proven treatment to all patients with
breast cancer.
B. Classify disease based on shared anatomical and
symptomatic features.
C. Tailor treatment based on the individual's unique genetic,
biomarker, and phenotypic profile.
D. Focus primarily on cost containment by using the least
expensive therapy first.
Answer: C
Rationale: Precision medicine moves beyond a one-size-fits-all
approach. It uses molecular analysis (like genomic testing) to
match treatments to the specific characteristics of the
individual patient and their disease.
