WGU D115 Advanced Pathophysiology Objective
Assessment Comprehensive Resource To Help You
Ace 2026-2027 Includes Frequently Tested
Questions With ELABORATED 100% Correct
COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. A 47-year-old female presents to a clinic to discuss the management of hot
flashes. She had a hysterectomy three years ago but still has her ovaries.
She tells an advanced practice registered nurse (APRN) that the hot flashes
are extremely bothersome to her and would like to start estradiol because
this medication worked well for her sister. She tells the APRN that she
smokes occasionally but is trying to quit.
Which medication is contraindicated for this patient?
Correct Answer: Oral estrogen
2. A 32-year-old female is discussing contraceptive options with an advanced
practice registered nurse (APRN). The patient is currently taking an oral
contraceptive pill and has no contraindications to estrogen therapy. She
tells the APRN that she is happy with the pill because it helps her skin but
really does not like having to take something every day. She is planning on
getting pregnant in 10-12 months when she is done with her graduate
degree.
Which recommendation should the APRN make for this patient?
Correct Answer: Vaginal contraceptive ring
3. A 46-year-old woman is seen for a gastrointestinal disorder and is diagnosed
with irritable bowel syndrome (IBS). She has been prescribed alosetron for
, severe symptoms associated with the disease.Which medication should the
advanced practice registered nurse (APRN) advise the patient to discontinue
to prevent drug interactions?
Correct Answer: Cimetidine
4. A patient has been on a long-term regimen of NSAIDs and needs a
medication that is approved to prevent gastric ulcers.
Which medication should an advanced practice registered nurse prescribe
for this patient?
Correct Answer: Misoprostol
5. A 32-year-old female presents to an advanced practice registered nurse
(APRN) with severe nausea and vomiting during pregnancy and requires
pharmaceutical therapy. The APRN knows that some medication solutions
should be avoided during pregnancy.
Which medication falls into this category?
Correct Answer: Chenodiol
6. An advanced practice registered nurse (APRN) is following up with a 48-
year-old female who has type 2 diabetes. The woman's self-monitored
fasting glucose results range from 79-126, and her HbA1c level is 7.5.
When does this result need to be rechecked by the APRN?
Correct Answer: Repeat in three months
7. A patient who is newly diagnosed with type 2 diabetes would like to try a
noninsulin medication that does not have the side effect of weight gain.
Which medication should an advanced practice registered nurse suggest?
Correct Answer: Metformin
8. A patient with type 2 diabetes is being seen by an advanced practice
registered nurse (APRN). The patient has a history of renal impairment and
takes metformin.
, Which potential medical complication should the APRN mention to the
patient?
Correct Answer: Metabolic acidosis
9. A patient with Graves disease comes into a clinic to tell her advanced
practice registered nurse (APRN) that she just found out that she has been
pregnant for six weeks.
Which medication should the APRN use for this patient?
Correct Answer: Propylthiouracil
10.An advanced practice registered nurse (APRN) is ordering levothyroxine and
is scheduling an appointment to check a patient's plasma levels to
determine the medication's effectiveness.
When should the APRN request the follow-up for this testing?
Correct Answer: In four weeks
11.A patient comes into a clinic with a new diagnosis of hyperthyroidism, and
an advanced practice registered nurse (APRN) decides to prescribe
methimazole over propylthiouracil.
Why did the APRN make this decision?
Correct Answer: It has a longer half-life.
12.A 42-year-old female asks an advanced practice registered nurse (APRN) for
help with weight loss. Her current body mass index (BMI) is 33.
Which goal is realistic for this patient?
Correct Answer: Target weight loss of 10%-15% in six months
13.An advanced practice registered nurse (APRN) is in the process of selecting
a medication to treat an adult patient for obesity. The patient has tried
lifestyle changes but has had limited success. The patient is currently taking
bupropion for depression.
Which medication is contraindicated for this patient?
, Correct Answer: Naltrexone/bupropion
14.A 40-year-old female is diagnosed with acute pyelonephritis with symptoms
of fever, chills, severe flank pain, dysuria, urinary frequency, and urinary
urgency. The patient is prescribed levofloxacin for 14 days.
Which bacterium is being treated in this patient?
Correct Answer: Escherichia coli
15.A 20-year-old patient with cancer is admitted to a medical surgical floor
with diarrhea. The stool cultures return positive for Clostridium difficile.
Which antibiotic should be prescribed for this patient?
Correct Answer: Metronidazole
16.A mother brings her one-year-old son to a routine checkup. It is almost flu
season, and she wants to get a flu vaccine for her son. This will be his first
flu vaccine. She is hoping the intranasal vaccine will be used so her son does
not have to be poked with a needle.
What are the flu vaccine options, if any, for this patient?
Correct Answer: For patients six months old to two years old, the influenza
vaccine administered intramuscularly is the only recommended option.
17.An adult female patient was placed on doxycycline. The patient states it has
made her stomach upset, and she wants to know if there are any problems
with her taking it with meals.
Which advice should be provided?
Correct Answer: Doxycycline may be given with food to decrease the upset
stomach and will only slightly decrease absorption of the drug.
18.A 75-year-old patient comes to an emergency room after eating shellfish.
He presents with shortness of breath, swollen eyes, and hives. The patient
was given a dose of epinephrine intravenously and is stable enough to
discharge.
Assessment Comprehensive Resource To Help You
Ace 2026-2027 Includes Frequently Tested
Questions With ELABORATED 100% Correct
COMPLETE SOLUTIONS
Guaranteed Pass First Attempt!!
Current Update!!
1. A 47-year-old female presents to a clinic to discuss the management of hot
flashes. She had a hysterectomy three years ago but still has her ovaries.
She tells an advanced practice registered nurse (APRN) that the hot flashes
are extremely bothersome to her and would like to start estradiol because
this medication worked well for her sister. She tells the APRN that she
smokes occasionally but is trying to quit.
Which medication is contraindicated for this patient?
Correct Answer: Oral estrogen
2. A 32-year-old female is discussing contraceptive options with an advanced
practice registered nurse (APRN). The patient is currently taking an oral
contraceptive pill and has no contraindications to estrogen therapy. She
tells the APRN that she is happy with the pill because it helps her skin but
really does not like having to take something every day. She is planning on
getting pregnant in 10-12 months when she is done with her graduate
degree.
Which recommendation should the APRN make for this patient?
Correct Answer: Vaginal contraceptive ring
3. A 46-year-old woman is seen for a gastrointestinal disorder and is diagnosed
with irritable bowel syndrome (IBS). She has been prescribed alosetron for
, severe symptoms associated with the disease.Which medication should the
advanced practice registered nurse (APRN) advise the patient to discontinue
to prevent drug interactions?
Correct Answer: Cimetidine
4. A patient has been on a long-term regimen of NSAIDs and needs a
medication that is approved to prevent gastric ulcers.
Which medication should an advanced practice registered nurse prescribe
for this patient?
Correct Answer: Misoprostol
5. A 32-year-old female presents to an advanced practice registered nurse
(APRN) with severe nausea and vomiting during pregnancy and requires
pharmaceutical therapy. The APRN knows that some medication solutions
should be avoided during pregnancy.
Which medication falls into this category?
Correct Answer: Chenodiol
6. An advanced practice registered nurse (APRN) is following up with a 48-
year-old female who has type 2 diabetes. The woman's self-monitored
fasting glucose results range from 79-126, and her HbA1c level is 7.5.
When does this result need to be rechecked by the APRN?
Correct Answer: Repeat in three months
7. A patient who is newly diagnosed with type 2 diabetes would like to try a
noninsulin medication that does not have the side effect of weight gain.
Which medication should an advanced practice registered nurse suggest?
Correct Answer: Metformin
8. A patient with type 2 diabetes is being seen by an advanced practice
registered nurse (APRN). The patient has a history of renal impairment and
takes metformin.
, Which potential medical complication should the APRN mention to the
patient?
Correct Answer: Metabolic acidosis
9. A patient with Graves disease comes into a clinic to tell her advanced
practice registered nurse (APRN) that she just found out that she has been
pregnant for six weeks.
Which medication should the APRN use for this patient?
Correct Answer: Propylthiouracil
10.An advanced practice registered nurse (APRN) is ordering levothyroxine and
is scheduling an appointment to check a patient's plasma levels to
determine the medication's effectiveness.
When should the APRN request the follow-up for this testing?
Correct Answer: In four weeks
11.A patient comes into a clinic with a new diagnosis of hyperthyroidism, and
an advanced practice registered nurse (APRN) decides to prescribe
methimazole over propylthiouracil.
Why did the APRN make this decision?
Correct Answer: It has a longer half-life.
12.A 42-year-old female asks an advanced practice registered nurse (APRN) for
help with weight loss. Her current body mass index (BMI) is 33.
Which goal is realistic for this patient?
Correct Answer: Target weight loss of 10%-15% in six months
13.An advanced practice registered nurse (APRN) is in the process of selecting
a medication to treat an adult patient for obesity. The patient has tried
lifestyle changes but has had limited success. The patient is currently taking
bupropion for depression.
Which medication is contraindicated for this patient?
, Correct Answer: Naltrexone/bupropion
14.A 40-year-old female is diagnosed with acute pyelonephritis with symptoms
of fever, chills, severe flank pain, dysuria, urinary frequency, and urinary
urgency. The patient is prescribed levofloxacin for 14 days.
Which bacterium is being treated in this patient?
Correct Answer: Escherichia coli
15.A 20-year-old patient with cancer is admitted to a medical surgical floor
with diarrhea. The stool cultures return positive for Clostridium difficile.
Which antibiotic should be prescribed for this patient?
Correct Answer: Metronidazole
16.A mother brings her one-year-old son to a routine checkup. It is almost flu
season, and she wants to get a flu vaccine for her son. This will be his first
flu vaccine. She is hoping the intranasal vaccine will be used so her son does
not have to be poked with a needle.
What are the flu vaccine options, if any, for this patient?
Correct Answer: For patients six months old to two years old, the influenza
vaccine administered intramuscularly is the only recommended option.
17.An adult female patient was placed on doxycycline. The patient states it has
made her stomach upset, and she wants to know if there are any problems
with her taking it with meals.
Which advice should be provided?
Correct Answer: Doxycycline may be given with food to decrease the upset
stomach and will only slightly decrease absorption of the drug.
18.A 75-year-old patient comes to an emergency room after eating shellfish.
He presents with shortness of breath, swollen eyes, and hives. The patient
was given a dose of epinephrine intravenously and is stable enough to
discharge.
