MOST RECENT EXAM 2026 ACTUAL COMPREHENSIVE
FREQUENTLY MOST TESTED REAL EXAM QUESTIONS
AND VERIFIED SOLUTIONS | ALREADY GRADED A+ |
NEWEST EXAM | JUST RELEASED!!
This class is associated with fewer neurological side effects
and effective for
both positive and negative symptoms: - ANSWER-
Second-generation
antipsychotics
A patient newly started on Clozapine will require ANC
Monitoring __________ x
___________ months - ANSWER-Weekly for
6 months
Parameters that require monitoring at baseline and ongoing
once a patient is
started on an SGA: - ANSWER-Weight, BMI, BP,
FBG/AIC, FLP
Symptoms of gynecomastia, erectile dysfunction, galactorrhea,
absence of menses, are all indicative of D2 blockade in the
________________ pathway and suggestive of
_______________. - ANSWER-Tuberoinfundibular,
hyperprolactin
,Blackbox warning assocaited with antipsychotic use in
dementia
________________________? - ANSWER-increased risk of
death and CVA events
_________________ may occur when stopping or reducing an
antipsychotic
medication. What are the characteristics? - ANSWER-
WIthdrawal. N/V/D
Antipsychotic is helpful and improve symptoms of
Tardive Dyskinesia: -
ANSWER-
clozaril
The primary managment of patients who experience tardive
dyskinesia: - ANSWER-Limiting drug exposure, stopping
antipsychotic (with slow taper), or switching to an SGA like
clozapril or quetiapine. Tetrabenazine or other VMAT2 inhibitor.
Amantadine, benzos, beta blockers, levitracitam,
In obese patients seeking antipsychotic medications, the
clinician should avoid medications that blocks: - ANSWER-
HT2C and 5-HT1A receptors, histamine H1 receptor and
dopamine D2 receptor among others. Antipsychotics differ in
their ability to block these receptors and this partly explains
their different liability to cause weight gain. Both olanzapine
,and clozapine, drugs with a high risk of weight gain, bind
strongly to the histamine H1 and serotonin 5-HT2C receptors.
Antipsychotics must occupy more than _______% of
_____________ receptors
to cause EPS: - ANSWER-75-80% of D2
receptors
This class is effective for only positive symptoms and can
in fact worsen negative symptoms due to decreased DA
in the mesocortical pathway: -
ANSWER-First generation
antipsychotics
Associated with metabolic side effects: - ANSWER-
Second-generation
antipsychotics
What are the metabolic side effects associated Atypical
antipsychotics: - ANSWER-Hyperglycemia, glucose
disregulation, lipid disturbance. Leading to HTN/DMII/metabolic
d/o
Includes medications such as Haloperidol,
chlorpromazine, fluphenazine,
perphenzine: -
ANSWER-FGA
, Includes medications such as Olanzapine, Quetiapine,
Risperidone, Clozapine,
etc: - ANSWER-
SGA
FGA reduce dopamine transmission by blocking
___________ receptors: -
ANSWER-
D2
SGA block both _____________ and _________________
receptors: -
ANSWER-D2 and Serotonin (usually with
5-HT2A)
High incidence of QTC prolongation, Tardive dyskinesia,
Neuroleptic Malignant
Syndrome (NMS), orthostatic hypotension: -
ANSWER-Typical
Patients on MAOI should be on a ____________________ diet -
ANSWER-low-
tyramine
diet
Clinicians switching from an SSRI to MAOI or vice versa should
note that it requires a ________________washout period due to
the risk of