Medical-Surgical Nursing MCQ Study Guide & Practice Test Bank – Fast Revision

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




High-Yield MCQs (20 Total)
1. The Practice of Medicine
1. Which principle best defines modern medical practice as
described in Harrison’s?
A. Disease-centered decision-making
B. Technology-driven diagnosis
C. Integration of evidence, clinical expertise, and patient values
D. Cost-minimization as the primary goal
Answer: C
Rationale: Harrison’s defines high-quality care as the
integration of best evidence, clinician expertise, and patient
preferences.
Citation: Harrison’s 22nd ed., Ch. 1 – The Practice of Medicine


2. Promoting Good Health

,2. From a nursing perspective, which intervention has the
greatest population-level impact on morbidity reduction?
A. Early pharmacologic therapy
B. Lifestyle and behavioral modification
C. Advanced diagnostic screening
D. Genetic testing
Answer: B
Rationale: Harrison’s emphasizes prevention through lifestyle
change as the most effective strategy for reducing chronic
disease burden.
Citation: Harrison’s 22nd ed., Ch. 2 – Promoting Good Health


3. Vaccine Opposition and Hesitancy
3. The most effective nursing response to vaccine hesitancy is:
A. Providing statistics only
B. Dismissing patient concerns
C. Empathetic communication addressing specific fears
D. Mandating vaccination without discussion
Answer: C
Rationale: Trust-based, empathetic dialogue improves vaccine
acceptance more than directive approaches.
Citation: Harrison’s 22nd ed., Ch. 3 – Vaccine Opposition and
Hesitancy


4. Decision-Making in Clinical Medicine

, 4. Shared decision-making is most appropriate when:
A. Evidence strongly favors one option
B. Multiple reasonable options exist
C. Emergency treatment is required
D. The patient lacks decisional capacity
Answer: B
Rationale: Harrison’s highlights shared decision-making when
benefits and risks vary by patient values.
Citation: Harrison’s 22nd ed., Ch. 4 – Decision-Making in Clinical
Medicine


5. Precision Medicine and Clinical Care
5. Precision medicine primarily aims to:
A. Replace clinical judgment
B. Standardize all treatments
C. Tailor care using biologic and genetic variability
D. Reduce patient involvement
Answer: C
Rationale: Precision medicine individualizes prevention and
treatment based on variability in genes, environment, and
lifestyle.
Citation: Harrison’s 22nd ed., Ch. 5 – Precision Medicine and
Clinical Care


6. Screening and Prevention of Disease