Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition Geralyn Frandsen
Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the bloodstream to their sites of action in
various body tissues, and eventually eliminated from the body. Curative agents are given to cure a disease process. In this case,
paroxeti ne hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff ects, such as sunscreen and local
anesthetics, act mainly at the site of application. Paroxet ine hydrochloride is not administered parenterally. Parenteral agents are
administered sub cutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring substance that has been cheGmRicAalDlyEmSoBdOifOieSd.TW.hCaOtMi s
b6
another name for this type o
f medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that have been chemically modified. Synthetic
drugs are more standardized in their chemic al characteristics, more consistent in their effects, and less likely to produce allergic react
ions. Biotechnology drugs involve manipulating DNA and RNA and recombining genes i nto hybrid molecules that can be inserted into living
organisms. Prototype drugs are the f irst drug of a particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf /2026/ 2027
,Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
C. Anti-inflammatory
D. Antihypertensive
ANS: A
Rationale: Drugs are classified according to their effects on particular body systems, their therapeutic uses, and their chemical
characteristics. Morphine is classified as a central ne rvous system depressant and will produce this effect in the client. A central nervous
syste m stimulant increases attention and raises mood. An anti-
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An antihypertensive agent reduces blood pressure.
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs to whi ch drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic nam GeRoAfDteEnSinBdOicOatSesTt.heCOdrug group (e.g., drugs with generic nam es ending in ―cillin‖ are penicillins). Selective serotonin
b6 b6 b6 b6
reuptake inhibitors are medicatio
ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur etics are medications that increase urine
output; diuretic is a broad classification, not a ge neric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
not the generic name.
PTS: 1 REF: p. 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug Administration ANS: D
b6
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf /2026/ 2027
,Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Rationale: The Food and Drug Administration approves drugs for over-the-
counter availability, including the transfer of drugs from prescription to OTC status, and may require clinical trials to determine the safety
and effectiveness of OTC use. The Pu blic Health Service is regulated by the state to maintain the health of individual citizens of the
state. The Federal Trade Commission regulates imports and exports throughout the nation. The Occupational Safety and Health
Administration regulates safety within the wo rkplace.
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma nufacture and distribution of narcotics, stimulants,
depressants, hallucinogens, and anaboli c steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powe rs and
responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Ac t restricted the importation, manufacture, sale, and use
of opium, cocaine, marijuana, and other drugs that the act d e f iGn eRd Aa Ds EnaSrBcoOtiOcsS. Th.eCSOhM
b6 erley Amendment of 1912 prohibited fraudulent claims of drug
effectiveness.
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nurse is responsible for maintaining an accurate count and record of the controlled substances on the nursing division. This
nursing action is regulated by which U.S. law or agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment ANS: C
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf /2026/ 2027
, Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Rationale: The Drug Enforcement Administration enforces the Controlled Substances Act
. Under this enforcement, nurses are responsible for storing controlled substances in lock ed containers, administering them only to the
people for whom they are prescribed, recor ding each dose given, and maintaining an accurate inventory. The Food, Drug, and Cosme tic
Act of 1938 revised and broadened FDA powers and responsibilities, giving the FDA control over drug safety. The Public Health Service is
regulated by the state to maintain the health of individual citizens of the state. The Sherley Amendment of 1912 prohibite d fraudulent
claims of drug effectiveness.
PTS: 1 REF: p. 7, Testing Procedure OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
8. In Phase 1 clinical trials, the potential uses and effects of a new drug are determined by which method?
A. Administering doses to healthy volunteers
B. Administering doses to people with the disease
C. Administering in placebo-controlled design
D. Calculating the risk-to-benefit ratio
ANS: A
Rationale: Phase 1 studies allow for the administration of the medication to healthy volun teers to determine safe dosages, routes of
administration, absorption, metabolism, excretio n, and toxicity. In Phase 2 studies, a few doses are given to a certain number of subjects
with the disease orGsRym
b6 ADptoESmBfoOrOwShiTc.hCthOeMd rug is being studied and responses are compare d with those of healthy subjects. Placebo-
6b b6
controlled designs are used in Phase 3 studies, in which half of the subjects receive the n ew drug and half receive the placebo.
Calculating the risk-to-
benefit ratio is used in Phase 2 studies to determine whether the potential benefits of the d rug outweigh the risks.
GRADESBOOST.COM
PTS: 1 REF: p. 7, Testing Procedure OBJ: 5
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
9. A new medication for the treatment of Alzheimer’s disease is being administered to a gro up of subjects with the disease. The subjects
receiving this medication are unaware of w hether they are being administered the medication or a placebo. This testing occurs in w hich
phase?
A. Phase 1
B. Phase 2
C. Phase 3
D. Phase 4
ANS: C
GRADESBOOST.COM #1 TEST BANKS WEBSITE
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf /2026/ 2027
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition Geralyn Frandsen
Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–
compulsive disorder has been prescribed oral paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the bloodstream to their sites of action in
various body tissues, and eventually eliminated from the body. Curative agents are given to cure a disease process. In this case,
paroxeti ne hydrochloride will control the symptoms but not cure the disorder. Drugs with local eff ects, such as sunscreen and local
anesthetics, act mainly at the site of application. Paroxet ine hydrochloride is not administered parenterally. Parenteral agents are
administered sub cutaneously, intramuscularly, or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring substance that has been cheGmRicAalDlyEmSoBdOifOieSd.TW.hCaOtMi s
b6
another name for this type o
f medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that have been chemically modified. Synthetic
drugs are more standardized in their chemic al characteristics, more consistent in their effects, and less likely to produce allergic react
ions. Biotechnology drugs involve manipulating DNA and RNA and recombining genes i nto hybrid molecules that can be inserted into living
organisms. Prototype drugs are the f irst drug of a particular group to be developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf /2026/ 2027
,Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
C. Anti-inflammatory
D. Antihypertensive
ANS: A
Rationale: Drugs are classified according to their effects on particular body systems, their therapeutic uses, and their chemical
characteristics. Morphine is classified as a central ne rvous system depressant and will produce this effect in the client. A central nervous
syste m stimulant increases attention and raises mood. An anti-
inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An antihypertensive agent reduces blood pressure.
PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
4. A client is administered amoxicillin. The generic name of this medication belongs to whi ch drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic nam GeRoAfDteEnSinBdOicOatSesTt.heCOdrug group (e.g., drugs with generic nam es ending in ―cillin‖ are penicillins). Selective serotonin
b6 b6 b6 b6
reuptake inhibitors are medicatio
ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur etics are medications that increase urine
output; diuretic is a broad classification, not a ge neric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
not the generic name.
PTS: 1 REF: p. 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug Administration ANS: D
b6
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf /2026/ 2027
,Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Rationale: The Food and Drug Administration approves drugs for over-the-
counter availability, including the transfer of drugs from prescription to OTC status, and may require clinical trials to determine the safety
and effectiveness of OTC use. The Pu blic Health Service is regulated by the state to maintain the health of individual citizens of the
state. The Federal Trade Commission regulates imports and exports throughout the nation. The Occupational Safety and Health
Administration regulates safety within the wo rkplace.
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
6. In the U.S., the administration of anabolic steroids is regulated by which law?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Comprehensive Drug Abuse Prevention and Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
ANS: B
Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma nufacture and distribution of narcotics, stimulants,
depressants, hallucinogens, and anaboli c steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA powe rs and
responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Ac t restricted the importation, manufacture, sale, and use
of opium, cocaine, marijuana, and other drugs that the act d e f iGn eRd Aa Ds EnaSrBcoOtiOcsS. Th.eCSOhM
b6 erley Amendment of 1912 prohibited fraudulent claims of drug
effectiveness.
PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ: 3
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice
7. A nurse is responsible for maintaining an accurate count and record of the controlled substances on the nursing division. This
nursing action is regulated by which U.S. law or agency?
A. The Food, Drug, and Cosmetic Act of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment ANS: C
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf /2026/ 2027
, Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf
Rationale: The Drug Enforcement Administration enforces the Controlled Substances Act
. Under this enforcement, nurses are responsible for storing controlled substances in lock ed containers, administering them only to the
people for whom they are prescribed, recor ding each dose given, and maintaining an accurate inventory. The Food, Drug, and Cosme tic
Act of 1938 revised and broadened FDA powers and responsibilities, giving the FDA control over drug safety. The Public Health Service is
regulated by the state to maintain the health of individual citizens of the state. The Sherley Amendment of 1912 prohibite d fraudulent
claims of drug effectiveness.
PTS: 1 REF: p. 7, Testing Procedure OBJ: 4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
8. In Phase 1 clinical trials, the potential uses and effects of a new drug are determined by which method?
A. Administering doses to healthy volunteers
B. Administering doses to people with the disease
C. Administering in placebo-controlled design
D. Calculating the risk-to-benefit ratio
ANS: A
Rationale: Phase 1 studies allow for the administration of the medication to healthy volun teers to determine safe dosages, routes of
administration, absorption, metabolism, excretio n, and toxicity. In Phase 2 studies, a few doses are given to a certain number of subjects
with the disease orGsRym
b6 ADptoESmBfoOrOwShiTc.hCthOeMd rug is being studied and responses are compare d with those of healthy subjects. Placebo-
6b b6
controlled designs are used in Phase 3 studies, in which half of the subjects receive the n ew drug and half receive the placebo.
Calculating the risk-to-
benefit ratio is used in Phase 2 studies to determine whether the potential benefits of the d rug outweigh the risks.
GRADESBOOST.COM
PTS: 1 REF: p. 7, Testing Procedure OBJ: 5
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi es TOP: Chapter: 1: The Foundation of
Pharmacology: Quality and Safety KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
9. A new medication for the treatment of Alzheimer’s disease is being administered to a gro up of subjects with the disease. The subjects
receiving this medication are unaware of w hether they are being administered the medication or a placebo. This testing occurs in w hich
phase?
A. Phase 1
B. Phase 2
C. Phase 3
D. Phase 4
ANS: C
GRADESBOOST.COM #1 TEST BANKS WEBSITE
Abrams Clinical Drug Therapy Test Bank 13th Edition
Abrams Clinical Drug Therapy Test Bank 13th Edition.pdf /2026/ 2027
