Urate accumulation - ANSWER---->>>sodium urate crystals are deposited in tissues- group
of disorders collectively called gout- acute arthritis, chronic gouty arthritis, tophus, nephritis
Coagulative Necrosis - ANSWER---->>>kidneys, heart, adrenals- secondary to hypoxia
Liquefactive Necrosis - ANSWER---->>>nerve cells- brain- accumulation of pus
Caseous Necrosis - ANSWER---->>>lung disease- usually TB- tissue looks like clumped
cheese
Fat Necrosis - ANSWER---->>>breast, pancreas, abdominal structures- creates soaps
Gangrenous Necrosis - ANSWER---->>>Dry- dark shriveled skin
Wet- internal organs- can lead to death
Gas- from clostridium- antitoxins and hyperbaric therapy
Gout - ANSWER---->>>E. Disturbances in serum urate levels. Uncommon for < 30 years old.
P. Uric acid is deposited in the tissues of kidney, heart, earlobes, and joints.
C.M. inflammation, painful joints. Result of diuretic use or diet high in cream sauces, red
wine, or red meat
Rhabdomyolysis - ANSWER---->>>E. Cell hypoxia caused by severe muscle trauma,
hyperthermia, crush injuries, or severe dehydration
P. Hypoxia leads to cell death, cellular contents are released in bloodstream.
C.M. CK is 5x upper normal limit, muscle pain, weakness, dark, reddish-brown urine,
hypercalcemia, renal failure
Alpha Fetoprotein Origin - ANSWER---->>>Liver and germ cell tumors
Carcinoembryonic Antigen - ANSWER---->>>GI, pancreas, lung, breast tumors
, Beta Human Chorionic gonadotropin origin - ANSWER---->>>germ cell tumors
Prostate Specific Antigen - ANSWER---->>>prostate tumors
Carcino- - ANSWER---->>>from epithelial tissue- renal cell carcinoma
Sarco- - ANSWER---->>>from connective tissue- chondrosarcoma
-oma - ANSWER---->>>benign tumor- lipoma
Carcinoma in situ - ANSWER---->>>preinvasive epithelial malignant tumors of glandular or
squamous cells- cervix
-blastoma - ANSWER---->>>from blasts or immature cells- neuroblastoma
Lung ca metastasis - ANSWER---->>>Multiple organs including brain
Colorectal ca metastasis - ANSWER---->>>Liver, lungs
Testicular ca metastasis - ANSWER---->>>Liver, lungs, brain
Prostate ca metastasis - ANSWER---->>>Bones (especially lumbar spine), liver
Breast ca metastasis - ANSWER---->>>Liver, lungs, brain, bones
Head and neck ca metastasis - ANSWER---->>>Liver, bones, lymphatics
Ovarian ca metastasis - ANSWER---->>>Peritoneal surfaces, diaphragm, omentum, liver
Sarcoma metastasis - ANSWER---->>>Lungs
of disorders collectively called gout- acute arthritis, chronic gouty arthritis, tophus, nephritis
Coagulative Necrosis - ANSWER---->>>kidneys, heart, adrenals- secondary to hypoxia
Liquefactive Necrosis - ANSWER---->>>nerve cells- brain- accumulation of pus
Caseous Necrosis - ANSWER---->>>lung disease- usually TB- tissue looks like clumped
cheese
Fat Necrosis - ANSWER---->>>breast, pancreas, abdominal structures- creates soaps
Gangrenous Necrosis - ANSWER---->>>Dry- dark shriveled skin
Wet- internal organs- can lead to death
Gas- from clostridium- antitoxins and hyperbaric therapy
Gout - ANSWER---->>>E. Disturbances in serum urate levels. Uncommon for < 30 years old.
P. Uric acid is deposited in the tissues of kidney, heart, earlobes, and joints.
C.M. inflammation, painful joints. Result of diuretic use or diet high in cream sauces, red
wine, or red meat
Rhabdomyolysis - ANSWER---->>>E. Cell hypoxia caused by severe muscle trauma,
hyperthermia, crush injuries, or severe dehydration
P. Hypoxia leads to cell death, cellular contents are released in bloodstream.
C.M. CK is 5x upper normal limit, muscle pain, weakness, dark, reddish-brown urine,
hypercalcemia, renal failure
Alpha Fetoprotein Origin - ANSWER---->>>Liver and germ cell tumors
Carcinoembryonic Antigen - ANSWER---->>>GI, pancreas, lung, breast tumors
, Beta Human Chorionic gonadotropin origin - ANSWER---->>>germ cell tumors
Prostate Specific Antigen - ANSWER---->>>prostate tumors
Carcino- - ANSWER---->>>from epithelial tissue- renal cell carcinoma
Sarco- - ANSWER---->>>from connective tissue- chondrosarcoma
-oma - ANSWER---->>>benign tumor- lipoma
Carcinoma in situ - ANSWER---->>>preinvasive epithelial malignant tumors of glandular or
squamous cells- cervix
-blastoma - ANSWER---->>>from blasts or immature cells- neuroblastoma
Lung ca metastasis - ANSWER---->>>Multiple organs including brain
Colorectal ca metastasis - ANSWER---->>>Liver, lungs
Testicular ca metastasis - ANSWER---->>>Liver, lungs, brain
Prostate ca metastasis - ANSWER---->>>Bones (especially lumbar spine), liver
Breast ca metastasis - ANSWER---->>>Liver, lungs, brain, bones
Head and neck ca metastasis - ANSWER---->>>Liver, bones, lymphatics
Ovarian ca metastasis - ANSWER---->>>Peritoneal surfaces, diaphragm, omentum, liver
Sarcoma metastasis - ANSWER---->>>Lungs
