NR 507 WEEK 3- HYPERSENSITIVITY,
IMMUNODEFICIENCY, AND HEMATOLOGIC
DISORDERS EXAM WITH CORRECT QUESTIONS AND
A+ GRADED SOLUTIONS 2026
Hypersensitivity: Type 1 - correct answers-Type 1:
Allergic reaction, Mediated by IgE, Inflammation
due to mast cell degranulation
Local symptoms:
-itching
-rash
Systemic symptoms:
,-wheezing
Most dangerous = anaphylactic reaction
systemic response of hypotension, severe
bronchoconstriction
Main treatment: epinephrine reverses the effects
Hypersensitivity: Type 2 - correct answers-Type 2:
Cytotoxic reaction; tissue specific (ex: thyroid
tissue)
Macrophages are the primary effectors cells
involved
Can cause tissue damage or alter function
Grave's disease (hyperthyroidism) - example of
altering thyroid function, but does not destroy
thyroid tissue
,Incompatible blood type- example of cell/tissue
damage that occurs; severe transfusion reaction
occurs and the transfused erythrocytes are
destroyed by agglutination or complement-
mediated lysis.
Type 1 Hypersensitivity VS. Type 2 Hypersensitivity -
correct answers-Type 1 Hypersensitivity
Organ Specific
Antibody binds to the antigen on the cell surface
Type 2 Hypersensitivity
Not Organ Specific
Antibody binds to the soluble antigen outside the
cell surface that was released into the blood or
body fluids, and the complex is then deposited in
the tissues
, Hypersensitivity: Type 3 - Examples - correct
answers-Rheumatoid arthritis: Antigen/antibodies
are deposited in the joints
Systemic Lupus Erythematosus (SLE)- very closely
related to autoimmunity- antigen/antibodies
deposit in organs that cause tissue damage
Hypersensitivity: Type 4 - correct answers-Delayed
response
Does not involve antigen/antibody complexes like
Types 1, 2 and 3
Is T-cell mediated
Differentiating Between the Rash of a Type 1 vs.
Type 4 Reaction: - correct answers-Type 1:
Immediate hypersensitivity reactions, termed atopic
IMMUNODEFICIENCY, AND HEMATOLOGIC
DISORDERS EXAM WITH CORRECT QUESTIONS AND
A+ GRADED SOLUTIONS 2026
Hypersensitivity: Type 1 - correct answers-Type 1:
Allergic reaction, Mediated by IgE, Inflammation
due to mast cell degranulation
Local symptoms:
-itching
-rash
Systemic symptoms:
,-wheezing
Most dangerous = anaphylactic reaction
systemic response of hypotension, severe
bronchoconstriction
Main treatment: epinephrine reverses the effects
Hypersensitivity: Type 2 - correct answers-Type 2:
Cytotoxic reaction; tissue specific (ex: thyroid
tissue)
Macrophages are the primary effectors cells
involved
Can cause tissue damage or alter function
Grave's disease (hyperthyroidism) - example of
altering thyroid function, but does not destroy
thyroid tissue
,Incompatible blood type- example of cell/tissue
damage that occurs; severe transfusion reaction
occurs and the transfused erythrocytes are
destroyed by agglutination or complement-
mediated lysis.
Type 1 Hypersensitivity VS. Type 2 Hypersensitivity -
correct answers-Type 1 Hypersensitivity
Organ Specific
Antibody binds to the antigen on the cell surface
Type 2 Hypersensitivity
Not Organ Specific
Antibody binds to the soluble antigen outside the
cell surface that was released into the blood or
body fluids, and the complex is then deposited in
the tissues
, Hypersensitivity: Type 3 - Examples - correct
answers-Rheumatoid arthritis: Antigen/antibodies
are deposited in the joints
Systemic Lupus Erythematosus (SLE)- very closely
related to autoimmunity- antigen/antibodies
deposit in organs that cause tissue damage
Hypersensitivity: Type 4 - correct answers-Delayed
response
Does not involve antigen/antibody complexes like
Types 1, 2 and 3
Is T-cell mediated
Differentiating Between the Rash of a Type 1 vs.
Type 4 Reaction: - correct answers-Type 1:
Immediate hypersensitivity reactions, termed atopic
