Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. The Practice of Medicine
Which principle best defines modern clinical medicine as
described in Harrison’s?
A. Disease-centered decision-making
B. Technology-driven diagnosis
C. Integration of scientific evidence with patient values
D. Cost containment as the primary goal
Answer: C
Rationale: Harrison’s emphasizes evidence-based medicine
integrated with patient preferences and values.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
The Practice of Medicine
2. Promoting Good Health
,Which factor has the greatest population-level impact on
health outcomes?
A. Acute medical interventions
B. Genetic predisposition
C. Social and environmental determinants
D. Specialty care access
Answer: C
Rationale: Social determinants (education, income,
environment) drive health outcomes more than medical care
alone.
Citation: Harrison’s, 22nd ed., Promoting Good Health
3. Vaccine Opposition and Hesitancy
What is the most effective clinician response to vaccine
hesitancy?
A. Dismissing patient concerns
B. Providing factual data only
C. Empathetic, respectful dialogue addressing concerns
D. Refusing care until vaccination
Answer: C
Rationale: Harrison’s stresses trust-building and respectful
communication to improve vaccine acceptance.
Citation: Harrison’s, 22nd ed., Vaccine Opposition and Hesitancy
4. Decision-Making in Clinical Medicine
, Shared decision-making is most appropriate when:
A. Evidence clearly favors one option
B. Patient capacity is impaired
C. Multiple reasonable options exist
D. Emergency intervention is required
Answer: C
Rationale: Shared decision-making is critical when benefits and
risks are closely balanced.
Citation: Harrison’s, 22nd ed., Decision-Making in Clinical
Medicine
5. Precision Medicine and Clinical Care
Precision medicine primarily aims to:
A. Replace clinical judgment
B. Individualize care using genetic and molecular data
C. Reduce healthcare costs
D. Eliminate population-based guidelines
Answer: B
Rationale: Precision medicine integrates genomics and
biomarkers to tailor therapy.
Citation: Harrison’s, 22nd ed., Precision Medicine and Clinical
Care
6. Screening and Prevention of Disease
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. The Practice of Medicine
Which principle best defines modern clinical medicine as
described in Harrison’s?
A. Disease-centered decision-making
B. Technology-driven diagnosis
C. Integration of scientific evidence with patient values
D. Cost containment as the primary goal
Answer: C
Rationale: Harrison’s emphasizes evidence-based medicine
integrated with patient preferences and values.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
The Practice of Medicine
2. Promoting Good Health
,Which factor has the greatest population-level impact on
health outcomes?
A. Acute medical interventions
B. Genetic predisposition
C. Social and environmental determinants
D. Specialty care access
Answer: C
Rationale: Social determinants (education, income,
environment) drive health outcomes more than medical care
alone.
Citation: Harrison’s, 22nd ed., Promoting Good Health
3. Vaccine Opposition and Hesitancy
What is the most effective clinician response to vaccine
hesitancy?
A. Dismissing patient concerns
B. Providing factual data only
C. Empathetic, respectful dialogue addressing concerns
D. Refusing care until vaccination
Answer: C
Rationale: Harrison’s stresses trust-building and respectful
communication to improve vaccine acceptance.
Citation: Harrison’s, 22nd ed., Vaccine Opposition and Hesitancy
4. Decision-Making in Clinical Medicine
, Shared decision-making is most appropriate when:
A. Evidence clearly favors one option
B. Patient capacity is impaired
C. Multiple reasonable options exist
D. Emergency intervention is required
Answer: C
Rationale: Shared decision-making is critical when benefits and
risks are closely balanced.
Citation: Harrison’s, 22nd ed., Decision-Making in Clinical
Medicine
5. Precision Medicine and Clinical Care
Precision medicine primarily aims to:
A. Replace clinical judgment
B. Individualize care using genetic and molecular data
C. Reduce healthcare costs
D. Eliminate population-based guidelines
Answer: B
Rationale: Precision medicine integrates genomics and
biomarkers to tailor therapy.
Citation: Harrison’s, 22nd ed., Precision Medicine and Clinical
Care
6. Screening and Prevention of Disease
