PMHNP CERTIFICATION EXAM QUESTIONS
AND ANSWERS 2026 COMPREHENSIVE EXAM
SCRIPT FULL QUESTIONS AND CORRECT
ANSWERS
◉ genetic testing FDA required in people of Asian descent. Answer:
presence of HLA-B*1502 allel
inherited variant of HLA-B gene
prior to prescribing carbamazepine d/t risk of steven Johnson
syndrome and toxic epidermal necrolysis TEN
◉ normal BMI. Answer: 20-25
◉ overweight BMI. Answer: 26-29
◉ obese BMI. Answer: 30-35
◉ what to watch for if on psychtropics such as carbamazepine
(Tegretol) or clozapine. Answer: elevated temp
agranulocytosis
,◉ steven Johnson syndrome med risk. Answer: carbamazepine or
lamotrigine
◉ blurry vision side effect in psychotropics. Answer: anticholinergic
side effect
Seroquel may cause cataracts
◉ what can both lithium and anorexia nervosa cause. Answer:
peripheral edema
◉ Free thyroxine T4 normal levels. Answer: 0.8-2.8ng/dL
◉ interfering factors of Free T4. Answer: values can be increased
during tx with heparin, aspirin, and propranolol
values can be decreased during tx with furosemide (Lasix) or
Methadone
◉ TSH values can be increased during therapy with what. Answer:
lithium
◉ systemic effects of hypothyroidism. Answer: decreased T4 and
increased TSH
mimics symptoms of unipolar mood dx
,◉ systemic effects of hyperthyroidism. Answer: increased T4 and
decreased TSH
may mimic symptoms of bipolar affective disorders
◉ interfering factors of calcium levels. Answer: values can be
increased by excessive ingestion of milk or during tx with lithium,
thiazide diuretics, alkaline antacids, or vitamin D
-values can be decreased during tx with anticonvulsants, aspirin,
calcitonin, corticosteroids, heparin, laxatives, diuretics, albuterol,
and oral contraceptives
◉ magnesium is a cause of neuromuscular what. Answer:
excitability
◉ interfering factors of magnesium levels. Answer: values can be
increased by drugs such as antacids, laxatives containing mg,
salicylates, and lithium
◉ interfering factors of ALT levels. Answer: values can be increased
with Tylenol, allopurinol, aspirin, ampicillin, carbamazepine,
cephalosporins, codeine, digitalis, indomethacin, heparin, isoniazid,
methotrexate, methyldopa, oral contraceptives, phenothiazines,
propranolol, tetracycline, and verapamil
, ◉ GGT is used to evaluate and monitor clients with what. Answer:
known or suspected alcohol abuse
levels rise even after ingestion of small amounts of alcohol
◉ primary preventions. Answer: aimed at decreasing the incidence
(number of new cases) of mental disorders
helping people avoid stressors or cope with them more adaptively
◉ secondary prevention. Answer: aimed at decreasing the
prevalence (number of existing cases) of mental disorders
early case finding
screening
prompt and effective tx
◉ tertiary prevention. Answer: aimed at decreasing the disability
and severity of mental disorder
rehabilitative services
avoidance or postponement of complications
◉ drug steady state. Answer: drugs usually are administered once
every half-life to achieve this
it takes approx. 5 half lives to achieve a steady state and 5 half lives
to completely eliminate a drug
AND ANSWERS 2026 COMPREHENSIVE EXAM
SCRIPT FULL QUESTIONS AND CORRECT
ANSWERS
◉ genetic testing FDA required in people of Asian descent. Answer:
presence of HLA-B*1502 allel
inherited variant of HLA-B gene
prior to prescribing carbamazepine d/t risk of steven Johnson
syndrome and toxic epidermal necrolysis TEN
◉ normal BMI. Answer: 20-25
◉ overweight BMI. Answer: 26-29
◉ obese BMI. Answer: 30-35
◉ what to watch for if on psychtropics such as carbamazepine
(Tegretol) or clozapine. Answer: elevated temp
agranulocytosis
,◉ steven Johnson syndrome med risk. Answer: carbamazepine or
lamotrigine
◉ blurry vision side effect in psychotropics. Answer: anticholinergic
side effect
Seroquel may cause cataracts
◉ what can both lithium and anorexia nervosa cause. Answer:
peripheral edema
◉ Free thyroxine T4 normal levels. Answer: 0.8-2.8ng/dL
◉ interfering factors of Free T4. Answer: values can be increased
during tx with heparin, aspirin, and propranolol
values can be decreased during tx with furosemide (Lasix) or
Methadone
◉ TSH values can be increased during therapy with what. Answer:
lithium
◉ systemic effects of hypothyroidism. Answer: decreased T4 and
increased TSH
mimics symptoms of unipolar mood dx
,◉ systemic effects of hyperthyroidism. Answer: increased T4 and
decreased TSH
may mimic symptoms of bipolar affective disorders
◉ interfering factors of calcium levels. Answer: values can be
increased by excessive ingestion of milk or during tx with lithium,
thiazide diuretics, alkaline antacids, or vitamin D
-values can be decreased during tx with anticonvulsants, aspirin,
calcitonin, corticosteroids, heparin, laxatives, diuretics, albuterol,
and oral contraceptives
◉ magnesium is a cause of neuromuscular what. Answer:
excitability
◉ interfering factors of magnesium levels. Answer: values can be
increased by drugs such as antacids, laxatives containing mg,
salicylates, and lithium
◉ interfering factors of ALT levels. Answer: values can be increased
with Tylenol, allopurinol, aspirin, ampicillin, carbamazepine,
cephalosporins, codeine, digitalis, indomethacin, heparin, isoniazid,
methotrexate, methyldopa, oral contraceptives, phenothiazines,
propranolol, tetracycline, and verapamil
, ◉ GGT is used to evaluate and monitor clients with what. Answer:
known or suspected alcohol abuse
levels rise even after ingestion of small amounts of alcohol
◉ primary preventions. Answer: aimed at decreasing the incidence
(number of new cases) of mental disorders
helping people avoid stressors or cope with them more adaptively
◉ secondary prevention. Answer: aimed at decreasing the
prevalence (number of existing cases) of mental disorders
early case finding
screening
prompt and effective tx
◉ tertiary prevention. Answer: aimed at decreasing the disability
and severity of mental disorder
rehabilitative services
avoidance or postponement of complications
◉ drug steady state. Answer: drugs usually are administered once
every half-life to achieve this
it takes approx. 5 half lives to achieve a steady state and 5 half lives
to completely eliminate a drug
