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BIOD 152 A&P 2 Lab 6 - Histology of Body Systems
(Liver, Pancreas, Small intestines, Endocrine system, Reproductive & Urinary systems)
Looking at the liver under the microscope
• Liver is made up of a lot of cylinders called Hepatic lobules.
• The hepatic lobules are made up of sheets of liver cells called Hepatocytes
• There is a center vein that passes through the middle of the hepatic lobules
that drain the blood from the microscopic structures and then eventually the
liver itself.
• The interior of the liver under the microscope- think of spreading open a book
cover to cover
o The whole represents the central vein
o Each page of the book represents a sheet of the hepatocyte
• In between each sheet of hepatocyte there are channels called Sinusoids.
o Sinusoids are blood channels that lead away from the central vein in the
hepatic
lobules.
o Sinusoids contain some phagocytic cells (can’t see under the microscope)
▪ Kupffer Cells- work to clean the blood and remove any debris
from theblood in the liver
• Hepatic Lobule under the microscope at the lowest power:
o The white dot in the center of
the lobule is the central vein (will eventually drain into the hepatic vein)
o Increasing the magnification:
▪ The red-ish areas
are the hepatocytes. The white lines in between the red areas are the
sinusoids.
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LOOKING AT THE PANCREAS UNDER THE MICROSCOPE
• Pancreas is a gland in the digestive system and considered endocrine and
exocrine glands.
o The endocrine portion- secretes hormones like insulin and glucagon to
control the blood sugar levels in our body
o The exocrine portion- secretes digestive enzymes and juices that
help to complete the digestive process.
o lowest power: can see
several oddly shaped lobules. Each lobule has a boundary of a white line
around it.
o Higher magnification:
Some of the cells are different colors.
▪ The darker cells that are stained a dark pink- Acini Cells (digestive
cells)
• 98-99% of the pancreas is made up of the acini cells; they
make up the exocrine portion of the gland
• They secrete the pancreatic juices and enzymes that help
withdigestive
▪ The lighter color larger pink cell is called the Islets of Langerhan.
• It’s the endocrine portion of the gland that will produce
insulin and glucagon hormones to regulate our blood
sugar levels.
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BIOD 152 A&P 2 Lab 6 - Histology of Body Systems
(Liver, Pancreas, Small intestines, Endocrine system, Reproductive & Urinary systems)
Looking at the liver under the microscope
• Liver is made up of a lot of cylinders called Hepatic lobules.
• The hepatic lobules are made up of sheets of liver cells called Hepatocytes
• There is a center vein that passes through the middle of the hepatic lobules
that drain the blood from the microscopic structures and then eventually the
liver itself.
• The interior of the liver under the microscope- think of spreading open a book
cover to cover
o The whole represents the central vein
o Each page of the book represents a sheet of the hepatocyte
• In between each sheet of hepatocyte there are channels called Sinusoids.
o Sinusoids are blood channels that lead away from the central vein in the
hepatic
lobules.
o Sinusoids contain some phagocytic cells (can’t see under the microscope)
▪ Kupffer Cells- work to clean the blood and remove any debris
from theblood in the liver
• Hepatic Lobule under the microscope at the lowest power:
o The white dot in the center of
the lobule is the central vein (will eventually drain into the hepatic vein)
o Increasing the magnification:
▪ The red-ish areas
are the hepatocytes. The white lines in between the red areas are the
sinusoids.
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Distribution of this document is illegal extra per year?
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LOOKING AT THE PANCREAS UNDER THE MICROSCOPE
• Pancreas is a gland in the digestive system and considered endocrine and
exocrine glands.
o The endocrine portion- secretes hormones like insulin and glucagon to
control the blood sugar levels in our body
o The exocrine portion- secretes digestive enzymes and juices that
help to complete the digestive process.
o lowest power: can see
several oddly shaped lobules. Each lobule has a boundary of a white line
around it.
o Higher magnification:
Some of the cells are different colors.
▪ The darker cells that are stained a dark pink- Acini Cells (digestive
cells)
• 98-99% of the pancreas is made up of the acini cells; they
make up the exocrine portion of the gland
• They secrete the pancreatic juices and enzymes that help
withdigestive
▪ The lighter color larger pink cell is called the Islets of Langerhan.
• It’s the endocrine portion of the gland that will produce
insulin and glucagon hormones to regulate our blood
sugar levels.
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